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Page 1
Structural Basis for Glycerol Efflux and Selectivity of Human Aquaporin 7.
de Maré SW, Venskutonytė R, Eltschkner S, de Groot BL, Lindkvist-Petersson K. de Maré SW, et al. Among authors: eltschkner s. Structure. 2020 Feb 4;28(2):215-222.e3. doi: 10.1016/j.str.2019.11.011. Epub 2019 Dec 9. Structure. 2020. PMID: 31831212 Free article.
A Long Residence Time Enoyl-Reductase Inhibitor Explores an Extended Binding Region with Isoenzyme-Dependent Tautomer Adaptation and Differential Substrate-Binding Loop Closure.
Eltschkner S, Kehrein J, Le TA, Davoodi S, Merget B, Basak S, Weinrich JD, Schiebel J, Tonge PJ, Engels B, Sotriffer C, Kisker C. Eltschkner S, et al. ACS Infect Dis. 2021 Apr 9;7(4):746-758. doi: 10.1021/acsinfecdis.0c00437. Epub 2021 Mar 12. ACS Infect Dis. 2021. PMID: 33710875 Free PMC article.
Evaluating the Contribution of Transition-State Destabilization to Changes in the Residence Time of Triazole-Based InhA Inhibitors.
Spagnuolo LA, Eltschkner S, Yu W, Daryaee F, Davoodi S, Knudson SE, Allen EK, Merino J, Pschibul A, Moree B, Thivalapill N, Truglio JJ, Salafsky J, Slayden RA, Kisker C, Tonge PJ. Spagnuolo LA, et al. Among authors: eltschkner s. J Am Chem Soc. 2017 Mar 8;139(9):3417-3429. doi: 10.1021/jacs.6b11148. Epub 2017 Feb 22. J Am Chem Soc. 2017. PMID: 28151657 Free PMC article.
Rational design of broad spectrum antibacterial activity based on a clinically relevant enoyl-acyl carrier protein (ACP) reductase inhibitor.
Schiebel J, Chang A, Shah S, Lu Y, Liu L, Pan P, Hirschbeck MW, Tareilus M, Eltschkner S, Yu W, Cummings JE, Knudson SE, Bommineni GR, Walker SG, Slayden RA, Sotriffer CA, Tonge PJ, Kisker C. Schiebel J, et al. Among authors: eltschkner s. J Biol Chem. 2014 Jun 6;289(23):15987-6005. doi: 10.1074/jbc.M113.532804. Epub 2014 Apr 16. J Biol Chem. 2014. PMID: 24739388 Free PMC article.