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EPB41L4A-AS1 and UNC5B-AS1 have diagnostic and prognostic significance in osteosarcoma.
Yan Y, Liu X, Li Y, Yan J, Zhao P, Yang L. Yan Y, et al. J Orthop Surg Res. 2023 Mar 30;18(1):261. doi: 10.1186/s13018-023-03754-0. J Orthop Surg Res. 2023. PMID: 36998043 Free PMC article.
EPB41L4A-AS1 and UNC5B-AS1 levels correlated with SSS stage. Patients with high levels of EPB41L4A-AS1 and UNC5B-AS1 had significantly shorter survival times. EPB41L4A-AS1 and UNC5B-AS1 were independent prognostic indexes for overall survival. miR-1306-5p was …
EPB41L4A-AS1 and UNC5B-AS1 levels correlated with SSS stage. Patients with high levels of EPB41L4A-AS1 and UNC5B-AS1 had signi …
LncRNA EPB41L4A-AS1 Regulates Cell Proliferation, Apoptosis and Metastasis in Breast Cancer.
Yang F, Lv S. Yang F, et al. Ann Clin Lab Sci. 2022 Jan;52(1):3-11. Ann Clin Lab Sci. 2022. PMID: 35181612
In our previous study, we identified that lncRNA EPB41L4A antisense RNA 1 (EPB41L4A-AS1) was significantly downregulated in breast cancer. ...MATERIALS: To demonstrate the role of EPB41L4A-AS1 in breast cancer, we transfected breast cancer lines with pcDNA3.1 …
In our previous study, we identified that lncRNA EPB41L4A antisense RNA 1 (EPB41L4A-AS1) was significantly downregulated in br …
EPB41L4A-AS1 is required to maintain basal autophagy to modulates Abeta clearance.
Wang Z, Wang R, Niu L, Zhou X, Han J, Li K. Wang Z, et al. NPJ Aging. 2024 May 4;10(1):24. doi: 10.1038/s41514-024-00152-6. NPJ Aging. 2024. PMID: 38704365 Free PMC article.
In this study, we found that downregulated EPB41L4A-AS1 in AD inhibited neuroglial cells mediated-Abeta clearance by decreasing the expression levels of multiple autophagy-related genes. ...Collectively, this study reveals EPB41L4A-AS1 as an AD-related lncRNA via me …
In this study, we found that downregulated EPB41L4A-AS1 in AD inhibited neuroglial cells mediated-Abeta clearance by decreasing the e …
IncRNA EPB41L4A-AS1 Mitigates the Proliferation of Non-Small-Cell Lung Cancer Cells through the miR-105-5p/GIMAP6 Axis.
Dong B, Zhang F, Zhang W, Gao Y. Dong B, et al. Crit Rev Eukaryot Gene Expr. 2023;33(2):27-40. doi: 10.1615/CritRevEukaryotGeneExpr.2022044323. Crit Rev Eukaryot Gene Expr. 2023. PMID: 36734855
This study sought to investigate the functionality of lncRNA EPB41L4A antisense RNA 1 (lncRNA EPB41L4A-AS1) in the proliferation of NSCLC cells and provide a novel theoretical reference for NSCLC treatment. ...The subcellular localization of lncRNA EPB41L4A-A …
This study sought to investigate the functionality of lncRNA EPB41L4A antisense RNA 1 (lncRNA EPB41L4A-AS1) in the proliferati …
LncRNA EPB41L4A-AS1 regulates glycolysis and glutaminolysis by mediating nucleolar translocation of HDAC2.
Liao M, Liao W, Xu N, Li B, Liu F, Zhang S, Wang Y, Wang S, Zhu Y, Chen D, Xie W, Jiang Y, Cao L, Yang BB, Zhang Y. Liao M, et al. EBioMedicine. 2019 Mar;41:200-213. doi: 10.1016/j.ebiom.2019.01.035. Epub 2019 Feb 19. EBioMedicine. 2019. PMID: 30796006 Free PMC article.
In this study, we aimed to uncover the molecular mechanisms of lncRNA EPB41L4A-AS1 in regulating glycolysis and glutaminolysis in cancer cells. METHODS: The expression of EPB41L4A-AS1 in cancer patients was analyzed in TCGA and GEO datasets. ...FINDINGS: EPB41L4A …
In this study, we aimed to uncover the molecular mechanisms of lncRNA EPB41L4A-AS1 in regulating glycolysis and glutaminolysis in can …
Clinical prognostic implications of EPB41L4A expression in multiple myeloma.
Zhang W, Lai R, He X, Liu X, Zhang Y, Yang Z, Yang P, Wang J, Hu K, Yuan X, Zhang X, Liu W, Jing H. Zhang W, et al. J Cancer. 2020 Jan 1;11(3):619-629. doi: 10.7150/jca.33805. eCollection 2020. J Cancer. 2020. PMID: 31942185 Free PMC article.

High expression of EPB41L4A can predict good survival in MM (EFS: P < 0.0001; OS: P < 0.0001). We found that patients with relapsed MM had lower expression levels of EPB41L4A than those without recurrence (P = 0.0039). We also found that EPB41L4A can pr

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High expression of EPB41L4A can predict good survival in MM (EFS: P < 0.0001; OS: P < 0.0001). We found that patients with rela

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Characterizing the function of EPB41L4A in the predisposition to papillary thyroid carcinoma.
Comiskey DF Jr, He H, Liyanarachchi S, Sheikh MS, Hendrickson IV, Yu L, Brock PL, de la Chapelle A. Comiskey DF Jr, et al. Sci Rep. 2020 Nov 17;10(1):19984. doi: 10.1038/s41598-020-76606-0. Sci Rep. 2020. PMID: 33203992 Free PMC article.
While the index SNP, rs73227498, acted as a significant cis-eQTL for expression of EPB41L4A, rs17134155 was a significant cis-sQTL for the alternative splicing of a non-coding transcript of EPB41L4A, called EPB41L4A-203. ...Our results indicate that an enhanc …
While the index SNP, rs73227498, acted as a significant cis-eQTL for expression of EPB41L4A, rs17134155 was a significant cis-sQTL fo …
LncRNA EPB41L4A-AS2 represses Nasopharyngeal Carcinoma Metastasis by binding to YBX1 in the Nucleus and Sponging MiR-107 in the Cytoplasm.
Du M, Hu X, Jiang X, Yin L, Chen J, Wen J, Fan Y, Peng F, Qian L, Wu J, He X. Du M, et al. Int J Biol Sci. 2021 May 11;17(8):1963-1978. doi: 10.7150/ijbs.55557. eCollection 2021. Int J Biol Sci. 2021. PMID: 34131399 Free PMC article.
The univariate and multivariate survival assays confirmed that EPB41L4A-AS2 expression was an independent predictor of progression-free survival (PFS) in patients with NPC. ...In the cytoplasm, we found that EPB41L4A-AS2 blocked the invasion and migration of NPC cel …
The univariate and multivariate survival assays confirmed that EPB41L4A-AS2 expression was an independent predictor of progression-fr …
Downregulation of lncRNA EPB41L4A-AS1 Mediates Activation of MYD88-Dependent NF-kappaB Pathway in Diabetes-Related Inflammation.
Wang Z, Liao W, Liu F, Yang T, Xie W, Liao M, Gu D, Zhang Y. Wang Z, et al. Diabetes Metab Syndr Obes. 2021 Jan 20;14:265-277. doi: 10.2147/DMSO.S280765. eCollection 2021. Diabetes Metab Syndr Obes. 2021. PMID: 33505165 Free PMC article.
The relationship between EPB41L4A-AS1 and phospho-p65 was explored by Western blotting (WB) and immunofluorescence. ...These results demonstrate that EPB41L4A-AS1 is closely associated with inflammation in T2DM, and that low expression of EPB41L4A-AS1 may be …
The relationship between EPB41L4A-AS1 and phospho-p65 was explored by Western blotting (WB) and immunofluorescence. ...These results …
Persistent high glucose induced EPB41L4A-AS1 inhibits glucose uptake via GCN5 mediating crotonylation and acetylation of histones and non-histones.
Liao W, Xu N, Zhang H, Liao W, Wang Y, Wang S, Zhang S, Jiang Y, Xie W, Zhang Y. Liao W, et al. Clin Transl Med. 2022 Feb;12(2):e699. doi: 10.1002/ctm2.699. Clin Transl Med. 2022. PMID: 35184403 Free PMC article.
Herein, we study the detailed mechanism underlying the functions of lncRNA EPB41L4A-AS1in T2DM. METHODS: Data from GEO datasets were used to analyze the expression of EPB41L4A-AS1 between insulin resistance or type 2 diabetes patients and the healthy people. ...Cell …
Herein, we study the detailed mechanism underlying the functions of lncRNA EPB41L4A-AS1in T2DM. METHODS: Data from GEO datasets were …
71 results