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Page 1
Negative allosteric modulation of GluN1/GluN3 NMDA receptors.
Zhu Z, Yi F, Epplin MP, Liu D, Summer SL, Mizu R, Shaulsky G, XiangWei W, Tang W, Burger PB, Menaldino DS, Myers SJ, Liotta DC, Hansen KB, Yuan H, Traynelis SF. Zhu Z, et al. Among authors: epplin mp. Neuropharmacology. 2020 Oct 1;176:108117. doi: 10.1016/j.neuropharm.2020.108117. Epub 2020 May 7. Neuropharmacology. 2020. PMID: 32389749 Free PMC article.
Biased modulators of NMDA receptors control channel opening and ion selectivity.
Perszyk RE, Swanger SA, Shelley C, Khatri A, Fernandez-Cuervo G, Epplin MP, Zhang J, Le P, Bülow P, Garnier-Amblard E, Gangireddy PKR, Bassell GJ, Yuan H, Menaldino DS, Liotta DC, Liebeskind LS, Traynelis SF. Perszyk RE, et al. Among authors: epplin mp. Nat Chem Biol. 2020 Feb;16(2):188-196. doi: 10.1038/s41589-019-0449-5. Epub 2020 Jan 20. Nat Chem Biol. 2020. PMID: 31959964 Free PMC article.
Distinct GluN1 and GluN2 Structural Determinants for Subunit-Selective Positive Allosteric Modulation of N-Methyl-d-aspartate Receptors.
Strong KL, Epplin MP, Ogden KK, Burger PB, Kaiser TM, Wilding TJ, Kusumoto H, Camp CR, Shaulsky G, Bhattacharya S, Perszyk RE, Menaldino DS, McDaniel MJ, Zhang J, Le P, Banke TG, Hansen KB, Huettner JE, Liotta DC, Traynelis SF. Strong KL, et al. Among authors: epplin mp. ACS Chem Neurosci. 2021 Jan 6;12(1):79-98. doi: 10.1021/acschemneuro.0c00561. Epub 2020 Dec 16. ACS Chem Neurosci. 2021. PMID: 33326224 Free PMC article.
The Structure-Activity Relationship of a Tetrahydroisoquinoline Class of N-Methyl-d-Aspartate Receptor Modulators that Potentiates GluN2B-Containing N-Methyl-d-Aspartate Receptors.
Strong KL, Epplin MP, Bacsa J, Butch CJ, Burger PB, Menaldino DS, Traynelis SF, Liotta DC. Strong KL, et al. Among authors: epplin mp. J Med Chem. 2017 Jul 13;60(13):5556-5585. doi: 10.1021/acs.jmedchem.7b00239. Epub 2017 Jun 26. J Med Chem. 2017. PMID: 28586221 Free PMC article.