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New dual 5-HT1A and 5-HT7 receptor ligands derived from SYA16263.

Ofori E, Onyameh EK, Gonela UM, Voshavar C, Bricker B, Swanson TL, Eshleman AJ, Schmachtenberg JL, Bloom SH, Janowsky AJ, Ablordeppey SY. Ofori E, et al. Among authors: eshleman aj. Eur J Med Chem. 2021 Mar 15;214:113243. doi: 10.1016/j.ejmech.2021.113243. Epub 2021 Feb 3. Eur J Med Chem. 2021. PMID: 33582388 Free PMC article.

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Neural regulation of bone and the skeletal effects of serotonin (5-hydroxytryptamine).

Warden SJ, Bliziotes MM, Wiren KM, Eshleman AJ, Turner CH. Warden SJ, et al. Among authors: eshleman aj. Mol Cell Endocrinol. 2005 Oct 20;242(1-2):1-9. doi: 10.1016/j.mce.2005.06.005. Mol Cell Endocrinol. 2005. PMID: 16085354 Review.

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Fentanyl but not Morphine Interacts with Nonopioid Recombinant Human Neurotransmitter Receptors and Transporters.

Torralva R, Eshleman AJ, Swanson TL, Schmachtenberg JL, Schutzer WE, Bloom SH, Wolfrum KM, Reed JF, Janowsky A. Torralva R, et al. Among authors: eshleman aj. J Pharmacol Exp Ther. 2020 Sep;374(3):376-391. doi: 10.1124/jpet.120.265561. Epub 2020 Jun 8. J Pharmacol Exp Ther. 2020. PMID: 32513839 Free PMC article.

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Affinity, potency, efficacy, selectivity, and molecular modeling of substituted fentanyls at opioid receptors.

Eshleman AJ, Nagarajan S, Wolfrum KM, Reed JF, Nilsen A, Torralva R, Janowsky A. Eshleman AJ, et al. Biochem Pharmacol. 2020 Dec;182:114293. doi: 10.1016/j.bcp.2020.114293. Epub 2020 Oct 20. Biochem Pharmacol. 2020. PMID: 33091380

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Synthesis and Discovery of Arylpiperidinylquinazolines: New Inhibitors of the Vesicular Monoamine Transporter.

Provencher BA, Eshleman AJ, Johnson RA, Shi X, Kryatova O, Nelson J, Tian J, Gonzalez M, Meltzer PC, Janowsky A. Provencher BA, et al. Among authors: eshleman aj. J Med Chem. 2018 Oct 25;61(20):9121-9131. doi: 10.1021/acs.jmedchem.8b00542. Epub 2018 Oct 4. J Med Chem. 2018. PMID: 30240563

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Verification of a genetic locus for methamphetamine intake and the impact of morphine.

Eastwood EC, Eshleman AJ, Janowsky A, Phillips TJ. Eastwood EC, et al. Among authors: eshleman aj. Mamm Genome. 2018 Apr;29(3-4):260-272. doi: 10.1007/s00335-017-9724-5. Epub 2017 Nov 10. Mamm Genome. 2018. PMID: 29127441 Free PMC article.

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Neurochemical pharmacology of psychoactive substituted N-benzylphenethylamines: High potency agonists at 5-HT_2A receptors.

Eshleman AJ, Wolfrum KM, Reed JF, Kim SO, Johnson RA, Janowsky A. Eshleman AJ, et al. Biochem Pharmacol. 2018 Dec;158:27-34. doi: 10.1016/j.bcp.2018.09.024. Epub 2018 Sep 25. Biochem Pharmacol. 2018. PMID: 30261175 Free PMC article.

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Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists.

Tosh DK, Ciancetta A, Mannes P, Warnick E, Janowsky A, Eshleman AJ, Gizewski E, Brust TF, Bohn LM, Auchampach JA, Gao ZG, Jacobson KA. Tosh DK, et al. Among authors: eshleman aj. ACS Omega. 2018 Oct 31;3(10):12658-12678. doi: 10.1021/acsomega.8b01237. Epub 2018 Oct 4. ACS Omega. 2018. PMID: 30411015 Free PMC article.

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Structure-activity relationships of bath salt components: substituted cathinones and benzofurans at biogenic amine transporters.

Eshleman AJ, Nagarajan S, Wolfrum KM, Reed JF, Swanson TL, Nilsen A, Janowsky A. Eshleman AJ, et al. Psychopharmacology (Berl). 2019 Mar;236(3):939-952. doi: 10.1007/s00213-018-5059-5. Epub 2018 Nov 5. Psychopharmacology (Berl). 2019. PMID: 30397775 Free PMC article.

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Activation of Trace Amine-Associated Receptor 1 Stimulates an Antiapoptotic Signal Cascade via Extracellular Signal-Regulated Kinase 1/2.

Shi X, Swanson TL, Miner NB, Eshleman AJ, Janowsky A. Shi X, et al. Among authors: eshleman aj. Mol Pharmacol. 2019 Oct;96(4):493-504. doi: 10.1124/mol.119.116798. Epub 2019 Aug 13. Mol Pharmacol. 2019. PMID: 31409621 Free PMC article.

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