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Page 1
From medium to endoplasmic reticulum: Tracing anticancer phenolato titanium(IV) complex by (19)F NMR detection.
Nahari G, Hoffman RE, Tshuva EY. Nahari G, et al. J Inorg Biochem. 2021 Aug;221:111492. doi: 10.1016/j.jinorgbio.2021.111492. Epub 2021 May 15. J Inorg Biochem. 2021. PMID: 34051630 Free article.
Herein, we employed a fluoro-substituted derivative, FenolaTi, for mechanistic analysis of the active species and its cellular target by quantitative (19)F NMR detection to reveal its biodistribution and reactivity in extracellular and intracellular matrices. ...
Herein, we employed a fluoro-substituted derivative, FenolaTi, for mechanistic analysis of the active species and its cellular target by qua …
Draft Genome Sequences of Six Flavobacterium psychrophilum Strains Isolated from Dead Juvenile Ayu (Plecoglossus altivelis altivelis) near the Mouth of the Nahari River, Kochi, Japan.
Yamashita H, Wada T, Kato Y, Ikeda T, Imajoh M. Yamashita H, et al. Microbiol Resour Announc. 2019 Jul 18;8(29):e00759-19. doi: 10.1128/MRA.00759-19. Microbiol Resour Announc. 2019. PMID: 31320441 Free PMC article.
In this study, we report the draft genome sequences of six F. psychrophilum strains isolated from the gills and skin of dead juvenile ayu near the mouth of the Nahari River....
In this study, we report the draft genome sequences of six F. psychrophilum strains isolated from the gills and skin of dead juvenile …
Effective Oral Administration of an Antitumorigenic Nanoformulated Titanium Complex.
Nahari G, Braitbard O, Larush L, Hochman J, Tshuva EY. Nahari G, et al. ChemMedChem. 2021 Jan 8;16(1):108-112. doi: 10.1002/cmdc.202000384. Epub 2020 Jul 30. ChemMedChem. 2021. PMID: 32657024
This is evidenced by similar NMR characteristics and similar in-vitro cytotoxicity toward murine (CT-26) and human (HT-29) colon cancer cells before and after incubation of nanoformulated phenolaTi (phenolaTi-F) at pH 2, unlike results with the unformulated form of the com …
This is evidenced by similar NMR characteristics and similar in-vitro cytotoxicity toward murine (CT-26) and human (HT-29) colon cancer cell …
Impact of Mineralizing Agents on Aluminum Distribution and Acidity of ZSM-5 Zeolites.
Al-Nahari S, Dib E, Cammarano C, Saint-Germes E, Massiot D, Sarou-Kanian V, Alonso B. Al-Nahari S, et al. Angew Chem Int Ed Engl. 2023 Feb 6;62(7):e202217992. doi: 10.1002/anie.202217992. Epub 2023 Jan 11. Angew Chem Int Ed Engl. 2023. PMID: 36541742 Free PMC article.
Herein, by studying a series of ZSM-5 zeolites over a broad range of Al content, we demonstrate how the nature of the mineralizing agent (F(-) or OH(-) ) used in hydrothermal syntheses directly impacts Al sites distribution. The proportions of Al sites, probed by (27) Al N …
Herein, by studying a series of ZSM-5 zeolites over a broad range of Al content, we demonstrate how the nature of the mineralizing agent ( …
Pharmacokinetics of daclatasvir in Egyptian adolescents with genotype-4 HCV infection.
Al-Nahari MM, Abbassi MM, Ebeid FS, Hassany M, El-Sayed MH, Farid SF. Al-Nahari MM, et al. Antivir Ther. 2020;25(2):101-110. doi: 10.3851/IMP3357. Antivir Ther. 2020. PMID: 32367815
Daclatasvir was best described by one compartment structural PK model with zero order absorption and first-order elimination. The absorption rate constant (K(0)), V/F, and CL/F of the final PopPK model of daclatasvir were 1.5/h, 52 l and 4.7 l/h, respectively. Body …
Daclatasvir was best described by one compartment structural PK model with zero order absorption and first-order elimination. The absorption …
Unveiling Therapeutic Potential: Targeting Fusobacterium nucleatum's Lipopolysaccharide Biosynthesis for Endodontic Infections-An In Silico Screening Study.
Boreak N, Alrajab EA, Nahari RA, Najmi LE, Masmali MA, Ghawi AA, Al Moaleem MM, Alhazmi MY, Maqbul AA. Boreak N, et al. Int J Mol Sci. 2024 Apr 11;25(8):4239. doi: 10.3390/ijms25084239. Int J Mol Sci. 2024. PMID: 38673822 Free PMC article.
Drugs targeting the molecular machinery of F. nucleatum will minimize pulp infection. LpxA and LpxD are early acyltransferases involved in the formation of lipid A, a major component of bacterial membranes. ...
Drugs targeting the molecular machinery of F. nucleatum will minimize pulp infection. LpxA and LpxD are early acyltransferases involv …
Novel NO-TZDs and trimethoxychalcone-based DHPMs: design, synthesis, and biological evaluation as potential VEGFR-2 inhibitors.
Mahnashi MH, Nahari M, Almasoudi H, Alhasaniah A, Elgazwi S, Abou-Salim MA. Mahnashi MH, et al. J Enzyme Inhib Med Chem. 2024 Dec;39(1):2358934. doi: 10.1080/14756366.2024.2358934. Epub 2024 Jun 21. J Enzyme Inhib Med Chem. 2024. PMID: 38904116 Free PMC article.
Among them, CDHPM-10e and CDHPM-10f demonstrated the highest MGI% of 147.69 and 140.24%, respectively. Compounds CDHPM-10a,b,d-f showed higher mean %inhibitory activity than the reference drug sorafenib (MGI% = 105.46%). ...
Among them, CDHPM-10e and CDHPM-10f demonstrated the highest MGI% of 147.69 and 140.24%, respectively. Compounds CDHPM-10a,b,d-f show …
Work readiness of newly graduated nurses transitioning to practice in Saudi Arabia: A cross-sectional study.
Almotairy M, Nahari A, Moafa H, Alanazi AA. Almotairy M, et al. J Nurs Manag. 2022 Nov;30(8):4523-4532. doi: 10.1111/jonm.13893. Epub 2022 Nov 11. J Nurs Manag. 2022. PMID: 36326491

There were significant mean differences in a) personal work characteristics based on the country (t = 5.582, p < 0.001) and university from which they graduated (f = 15.618, p < 0.001); b) organizational acumen based on having a second job (t = -2.18, p = 0.03), univ

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There were significant mean differences in a) personal work characteristics based on the country (t = 5.582, p < 0.001) and university fr

…
Ketamine-based Sedation Use in Mechanically Ventilated Critically Ill Patients with COVID-19: A Multicenter Cohort Study.
Aljuhani O, Al Sulaiman K, Korayem GB, Altebainawi AF, Alshaya A, Nahari M, Alsamnan K, Alkathiri MA, Al-Dosari BS, Alenazi AA, Alsohimi S, Alnajjar LI, Alfaifi M, AlQussair N, Alanazi RM, Alhmoud MF, Alanazi NL, Alkofide H, Alenezi AM, Vishwakarma R. Aljuhani O, et al. Saudi Pharm J. 2024 May;32(5):102061. doi: 10.1016/j.jsps.2024.102061. Epub 2024 Apr 3. Saudi Pharm J. 2024. PMID: 38596319 Free PMC article.
The primary outcome was the length of stay (LOS) in the hospital. P/F ratio differences, lactic acid normalization, MV duration, and mortality were considered secondary outcomes. ...
The primary outcome was the length of stay (LOS) in the hospital. P/F ratio differences, lactic acid normalization, MV duration, and …
The impact of comprehensive licensure review on nursing students' clinical competence, self-efficacy, and work readiness.
Innab A, Almotairy MM, Alqahtani N, Nahari A, Alghamdi R, Moafa H, Alshael D. Innab A, et al. Heliyon. 2024 Mar 26;10(7):e28506. doi: 10.1016/j.heliyon.2024.e28506. eCollection 2024 Apr 15. Heliyon. 2024. PMID: 38596111 Free PMC article.
Self-efficacy (beta = 0.353, p < 0.001) and clinical competence (beta = 0.251, p < 0.001) influenced work readiness (F [5, 226] = 21.03, p < 0.001) and accounted for 31.8% of the explained variability in work readiness. ...

Self-efficacy (beta = 0.353, p < 0.001) and clinical competence (beta = 0.251, p < 0.001) influenced work readiness (F [5, 226]

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11 results