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Hemoglobin and the origins of the concept of allosterism.
Edsall JT. Edsall JT. Fed Proc. 1980 Feb;39(2):226-35. Fed Proc. 1980. PMID: 6986293
Pauling proposed a simple model, involving only two constants, that fitted available data well. Haurowitz's demonstration that crystal structure changed on oxygenation (1938) gave the first evidence clearly pointing to a conformation change; in 1951 Wyman and Allen elabora …
Pauling proposed a simple model, involving only two constants, that fitted available data well. Haurowitz's demonstration that crysta …