Natural killer cell signal integration balances synapse symmetry and migration.
Culley FJ, Johnson M, Evans JH, Kumar S, Crilly R, Casasbuenas J, Schnyder T, Mehrabi M, Deonarain MP, Ushakov DS, Braud V, Roth G, Brock R, Köhler K, Davis DM.
Culley FJ, et al.
PLoS Biol. 2009 Jul;7(7):e1000159. doi: 10.1371/journal.pbio.1000159. Epub 2009 Jul 28.
PLoS Biol. 2009.
PMID: 19636352
Free PMC article.
In contrast, ligation of the activating receptor NKG2D induced symmetrical spreading of ruffled lamellipodia encompassing a dynamic ring of f-actin, concurrent with polarization towards a target cell and a "stop" signal. Ligation of both LFA-1 and NKG2D together resulted i …
In contrast, ligation of the activating receptor NKG2D induced symmetrical spreading of ruffled lamellipodia encompassing a dynamic ring of …