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Page 1
Inhibitor in Congenital Factor VII Deficiency; a Rare but Serious Therapeutic Challenge-A Systematic Literature Review.
Ramezanpour N, Zaker F, Biswas A, Dorgalaleh A. Ramezanpour N, et al. J Clin Med. 2021 Jan 8;10(2):211. doi: 10.3390/jcm10020211. J Clin Med. 2021. PMID: 33435610 Free PMC article. Review.
BACKGROUND: Congenital factor (F) VII deficiency is a rare coagulation factor deficiency with an estimated incidence of 1 per 500,000 individuals. ...
BACKGROUND: Congenital factor (F) VII deficiency is a rare coagulation factor deficiency with an estimated incidence of 1 per 500,000 …
Noninvasive prenatal diagnosis of congenital factor XIII deficiency in Iran.
Motlagh H, Dorgalaleh A, Tabibian S, Naderi M, Zaker F. Motlagh H, et al. Blood Coagul Fibrinolysis. 2022 Apr 1;33(3):167-170. doi: 10.1097/MBC.0000000000001121. Epub 2022 Jan 3. Blood Coagul Fibrinolysis. 2022. PMID: 34980832
Congenital factor (F) XIII deficiency is a rare coagulation factor deficiency that is inherited in an autosomal recessive manner. ...
Congenital factor (F) XIII deficiency is a rare coagulation factor deficiency that is inherited in an autosomal recessive manner. ...
Inhibition of Skp2 enhances doxorubicin-induced cell death in B cell precursor acute lymphoblastic leukemia.
Manafi Shabestari R, Chegeni R, Faranoush M, Zaker F, Safa M. Manafi Shabestari R, et al. Cell Biol Int. 2022 Jun;46(6):895-906. doi: 10.1002/cbin.11779. Epub 2022 Mar 13. Cell Biol Int. 2022. PMID: 35143089
S-phase kinase-associated protein 2 (Skp2) is a well-defined component of the Skp2-Culin1-F-box (SCF) E3 ubiquitin ligase complex, which is involved in cell cycle progression and considered a prognostic marker in cancers. ...
S-phase kinase-associated protein 2 (Skp2) is a well-defined component of the Skp2-Culin1-F-box (SCF) E3 ubiquitin ligase complex, wh …
Characterization of the diversity of type IV secretion system-encoding plasmids in Acinetobacter.
Nasser F, Gaudreau A, Lubega S, Zaker A, Xia X, Mer AS, D'Costa VM. Nasser F, et al. Emerg Microbes Infect. 2024 Dec;13(1):2320929. doi: 10.1080/22221751.2024.2320929. Epub 2024 Mar 26. Emerg Microbes Infect. 2024. PMID: 38530969 Free PMC article.
The epidemic multidrug-resistant A. baumannii ACICU harbours a plasmid encoding a Type IV Secretion System (T4SS) with homology to the E. coli F-plasmid, and plasmids with homologous gene clusters have been identified in several A. baumannii sequence types. ...
The epidemic multidrug-resistant A. baumannii ACICU harbours a plasmid encoding a Type IV Secretion System (T4SS) with homology to the E. co …
Direct inference of Patlak parametric images in whole-body PET/CT imaging using convolutional neural networks.
Zaker N, Haddad K, Faghihi R, Arabi H, Zaidi H. Zaker N, et al. Eur J Nucl Med Mol Imaging. 2022 Oct;49(12):4048-4063. doi: 10.1007/s00259-022-05867-w. Epub 2022 Jun 18. Eur J Nucl Med Mol Imaging. 2022. PMID: 35716176 Free PMC article.
PURPOSE: This study proposed and investigated the feasibility of estimating Patlak-derived influx rate constant (K(i)) from standardized uptake value (SUV) and/or dynamic PET image series. METHODS: Whole-body (18)F-FDG dynamic PET images of 19 subjects consisting of 13 fra …
PURPOSE: This study proposed and investigated the feasibility of estimating Patlak-derived influx rate constant (K(i)) from standardized upt …
Assessment of Lesion Detectability in Dynamic Whole-Body PET Imaging Using Compartmental and Patlak Parametric Mapping.
Zaker N, Kotasidis F, Garibotto V, Zaidi H. Zaker N, et al. Clin Nucl Med. 2020 May;45(5):e221-e231. doi: 10.1097/RLU.0000000000002954. Clin Nucl Med. 2020. PMID: 32108696
In this work, we assessed the capability of multipass WB F-FDG PET parametric imaging in terms of lesion detectability through qualitative and quantitative evaluation of simulation and clinical studies. ...
In this work, we assessed the capability of multipass WB F-FDG PET parametric imaging in terms of lesion detectability through qualit …
Factor VII Padua in Iran: A Study on 150 Patients With Factor VII Deficiency.
Safdari SM, Barati M, Hosseini S, Kalantar E, Zaker F, Dorgalaleh A. Safdari SM, et al. Haemophilia. 2025 Jul;31(4):771-779. doi: 10.1111/hae.70068. Epub 2025 May 27. Haemophilia. 2025. PMID: 40421903
INTRODUCTION: Factor (F) VII Padua is an ultra-rare type II FVII deficiency characterized by discrepancies in FVII activity across different thromboplastin types. ...
INTRODUCTION: Factor (F) VII Padua is an ultra-rare type II FVII deficiency characterized by discrepancies in FVII activity across di …
Relationship Between Single-Nucleotide Polymorphisms of Tumor Necrosis Factor Alpha, Interleukin-10, Factor II and Factor V with Risk of Inhibitor Development in Patients with Severe Hemophilia A.
Soori S, Dadashizadeh G, Dorgalaleh A, Tabibian S, Keramati MR, Alizadeh S, Hosseini MS, Zaker F, Shams M. Soori S, et al. Cardiovasc Hematol Disord Drug Targets. 2019;19(3):228-232. doi: 10.2174/1871529X19666190206152315. Cardiovasc Hematol Disord Drug Targets. 2019. PMID: 30727925
BACKGROUND: About one-fourth of patients with hemophilia A (HA) develop alloantibodies against factor (F) VIII, as the main treatment challenge. Here, we assessed the relationship between interleukin-10 (IL-10), tumor necrosis factor alpha (TNF-alpha), FII and FV polymorph …
BACKGROUND: About one-fourth of patients with hemophilia A (HA) develop alloantibodies against factor (F) VIII, as the main treatment …
From sea to cure: Discovery of marine-derived therapeutics against Fusarium solani in shrimps for enhancing aquaculture sustainability.
Siam AA, Paul AK, Joyoti SA, Hossain MI, Siddiquee NH, Zaker BB, Farabi A, Paul SK. Siam AA, et al. PLoS One. 2025 Oct 31;20(10):e0336107. doi: 10.1371/journal.pone.0336107. eCollection 2025. PLoS One. 2025. PMID: 41171878 Free PMC article.
In silico drug design has been evaluated as an innovative treatment for black gill disease in shrimps caused by F. solani. Initially, molecular docking targeted the Glutamine synthetase (AF-Q9UUN6-F1-v4), utilising a set of 1,191 seaweed metabolites found in the Seaweed me …
In silico drug design has been evaluated as an innovative treatment for black gill disease in shrimps caused by F. solani. Initially, …
Paternal exposure to arsenic resulted in oxidative stress, autophagy, and mitochondrial impairments in the HPG axis of pubertal male offspring.
Ommati MM, Heidari R, Manthari RK, Tikka Chiranjeevi S, Niu R, Sun Z, Sabouri S, Zamiri MJ, Zaker L, Yuan J, Wang J, Zhang J, Wang J. Ommati MM, et al. Chemosphere. 2019 Dec;236:124325. doi: 10.1016/j.chemosphere.2019.07.056. Epub 2019 Jul 15. Chemosphere. 2019. PMID: 31326754
Meanwhile, concomitant with a dose-dependent increment in the gene expression of ATG3, ATG5, Beclin, as well as protein expression of P62, ATG12, and Beclin in HPG axis tissues; a dose-dependent decrease in PI3K and mTOR gene expression was recorded in the HPG tissues of pubertal …
Meanwhile, concomitant with a dose-dependent increment in the gene expression of ATG3, ATG5, Beclin, as well as protein expression of P62, A …