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Page 1
Biomarkers for posttraumatic epilepsy.
Pitkänen A, Paananen T, Kyyriäinen J, Das Gupta S, Heiskanen M, Vuokila N, Bañuelos-Cabrera I, Lapinlampi N, Kajevu N, Andrade P, Ciszek R, Lara-Valderrábano L, Ekolle Ndode-Ekane X, Puhakka N. Pitkänen A, et al. Epilepsy Behav. 2021 Aug;121(Pt B):107080. doi: 10.1016/j.yebeh.2020.107080. Epub 2020 Apr 18. Epilepsy Behav. 2021. PMID: 32317161 Review.
The seven BEST biomarker categories include the following: (a) susceptibility/risk biomarkers, (b) diagnostic biomarkers, (c) monitoring biomarkers, (d) prognostic biomarkers, (e) predictive biomarkers, (f) pharmacodynamic/response biomarkers, and (g) safety biomarkers. We …
The seven BEST biomarker categories include the following: (a) susceptibility/risk biomarkers, (b) diagnostic biomarkers, (c) monitoring bio …
Abstracts from Hydrocephalus 2016.
Adam A, Robison J, Lu J, Jose R, Badran N, Vivas-Buitrago T, Rigamonti D, Sattar A, Omoush O, Hammad M, Dawood M, Maghaslah M, Belcher T, Carson K, Hoffberger J, Jusué Torres I, Foley S, Yasar S, Thai QA, Wemmer J, Klinge P, Al-Mutawa L, Al-Ghamdi H, Carson KA, Asgari M, de Zélicourt D, Kurtcuoglu V, Garnotel S, Salmon S, Balédent O, Lokossou A, Page G, Balardy L, Czosnyka Z, Payoux P, Schmidt EA, Zitoun M, Sevestre MA, Alperin N, Baudracco I, Craven C, Matloob S, Thompson S, Haylock Vize P, Thorne L, Watkins LD, Toma AK, Bechter K, Pong AC, Jugé L, Bilston LE, Cheng S, Bradley W, Hakim F, Ramón JF, Cárdenas MF, Davidson JS, García C, González D, Bermúdez S, Useche N, Mejía JA, Mayorga P, Cruz F, Martinez C, Matiz MC, Vallejo M, Ghotme K, Soto HA, Riveros D, Buitrago A, Mora M, Murcia L, Bermudez S, Cohen D, Dasgupta D, Curtis C, Domínguez L, Remolina AJ, Grijalba MA, Whitehouse KJ, Edwards RJ, Eleftheriou A, Lundin F, Fountas KN, Kapsalaki EZ, Smisson HF, Robinson JS, Fritsch MJ, Arouk W, Garzon M, Kang M, Sandhu K, Baghawatti D, Aquilina K, James G, Thompson D, Gehlen M, Schmid Daners M, Eklund A, Malm J, Gomez D, Guerra M, Jara M, Flores M, Vío K, Moreno I, Rodríguez S, Ortega … See abstract for full author list ➔ Adam A, et al. Fluids Barriers CNS. 2017 Jun 7;14(Suppl 1):15. doi: 10.1186/s12987-017-0054-5. Fluids Barriers CNS. 2017. PMID: 28929972 Free PMC article. No abstract available.
The complex structure of Fomes fomentarius represents an architectural design for high-performance ultralightweight materials.
Pylkkänen R, Werner D, Bishoyi A, Weil D, Scoppola E, Wagermaier W, Safeer A, Bahri S, Baldus M, Paananen A, Penttilä M, Szilvay GR, Mohammadi P. Pylkkänen R, et al. Sci Adv. 2023 Feb 22;9(8):eade5417. doi: 10.1126/sciadv.ade5417. Epub 2023 Feb 22. Sci Adv. 2023. PMID: 36812306 Free PMC article.
Here, we show with detailed structural, chemical, and mechanical characterization that Fomes fomentarius is an exception, and its architectural design is a source of inspiration for an emerging class of ultralightweight high-performance materials. Our findings reveal that F …
Here, we show with detailed structural, chemical, and mechanical characterization that Fomes fomentarius is an exception, and its architectu …
A synthetically modified hydrophobin showing enhanced fluorous affinity.
Milani R, Pirrie L, Gazzera L, Paananen A, Baldrighi M, Monogioudi E, Cavallo G, Linder M, Resnati G, Metrangolo P. Milani R, et al. J Colloid Interface Sci. 2015 Jun 15;448:140-7. doi: 10.1016/j.jcis.2015.02.003. Epub 2015 Feb 9. J Colloid Interface Sci. 2015. PMID: 25725398 Free article.
In order to increase their fluorophilicity further, here we report the preparation of a unique fluorous-modified hydrophobin, named F-HFBI. F-HFBI was found to be more effective than its wild-type parent protein HFBI at reducing interface tension of water at both ai …
In order to increase their fluorophilicity further, here we report the preparation of a unique fluorous-modified hydrophobin, named F …
Nanocellulose-short peptide self-assembly for improved mechanical strength and barrier performance.
Marchetti A, Marelli E, Bergamaschi G, Lahtinen P, Paananen A, Linder M, Pigliacelli C, Metrangolo P. Marchetti A, et al. J Mater Chem B. 2024 Sep 25;12(37):9229-9237. doi: 10.1039/d4tb01359j. J Mater Chem B. 2024. PMID: 39176991 Free PMC article.
Herein, we propose a noncovalent approach employing a set of short peptides - DFNKF, DF(I)NKF, and DF(F(5))NKF - as supramolecular additives to engineer hybrid hydrogels and films based on unfunctionalized CNF. ...Notably, the presence of fluorine in the CNF-DF(F(5) …
Herein, we propose a noncovalent approach employing a set of short peptides - DFNKF, DF(I)NKF, and DF(F(5))NKF - as supramolecular ad …
Evaluation of exposure to man-made vitreous fibers by nasal lavage.
Paananen H, Holopainen M, Kalliokoski P, Kangas J, Kotilainen M, Pennanen S, Savolainen H, Tossavainen A, Luoto K. Paananen H, et al. J Occup Environ Hyg. 2004 Feb;1(2):82-7. doi: 10.1080/15459620490275713. J Occup Environ Hyg. 2004. PMID: 15204882
In nasal lavage samples, the mean concentration of MMVF (length >1.5 microm) was 3260 f/ mL in Factory 1, 1680 f/mL in Factory 2, and below 500 f/mL in the control group. ...The airborne concentrations of MMVF both in the breathing zone and fixed-point sam …
In nasal lavage samples, the mean concentration of MMVF (length >1.5 microm) was 3260 f/ mL in Factory 1, 1680 f/mL in Fact …
Early Increase in Cortical T2 Relaxation Is a Prognostic Biomarker for the Evolution of Severe Cortical Damage, but Not for Epileptogenesis, after Experimental Traumatic Brain Injury.
Manninen E, Chary K, Lapinlampi N, Andrade P, Paananen T, Sierra A, Tohka J, Gröhn O, Pitkänen A. Manninen E, et al. J Neurotrauma. 2020 Dec 1;37(23):2580-2594. doi: 10.1089/neu.2019.6796. Epub 2020 Jun 26. J Neurotrauma. 2020. PMID: 32349620

Multiple linear regression analysis indicated that T(2)-based classification of lesion volume at day 2 and day 7 post-TBI explained the necrotic lesion volume with greatly increased T(2) (>102 ms) at day 21 post-TBI (F((13,103)) = 52.5; p < 0.001; R(2) = 0.87; adjust

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Multiple linear regression analysis indicated that T(2)-based classification of lesion volume at day 2 and day 7 post-TBI explained the necr …