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2005 2
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The efficacy of dihydroartemisinin-piperaquine and artemether-lumefantrine with and without primaquine on Plasmodium vivax recurrence: A systematic review and individual patient data meta-analysis.
Commons RJ, Simpson JA, Thriemer K, Abreha T, Adam I, Anstey NM, Assefa A, Awab GR, Baird JK, Barber BE, Chu CS, Dahal P, Daher A, Davis TME, Dondorp AM, Grigg MJ, Humphreys GS, Hwang J, Karunajeewa H, Laman M, Lidia K, Moore BR, Mueller I, Nosten F, Pasaribu AP, Pereira DB, Phyo AP, Poespoprodjo JR, Sibley CH, Stepniewska K, Sutanto I, Thwaites G, Hien TT, White NJ, William T, Woodrow CJ, Guerin PJ, Price RN. Commons RJ, et al. PLoS Med. 2019 Oct 4;16(10):e1002928. doi: 10.1371/journal.pmed.1002928. eCollection 2019 Oct. PLoS Med. 2019. PMID: 31584960 Free PMC article.
We found that delaying P. vivax recurrence was associated with a small but significant improvement in haemoglobin. These results highlight the benefits of PQ radical cure and also the provision of blood-stage antimalarial agents with prolonged post-treatment prophylaxis... …
We found that delaying P. vivax recurrence was associated with a small but significant improvement in haemoglobin. These results highlight t …
Artemether-lumefantrine dosing for malaria treatment in young children and pregnant women: A pharmacokinetic-pharmacodynamic meta-analysis.
Kloprogge F, Workman L, Borrmann S, Tékété M, Lefèvre G, Hamed K, Piola P, Ursing J, Kofoed PE, Mårtensson A, Ngasala B, Björkman A, Ashton M, Friberg Hietala S, Aweeka F, Parikh S, Mwai L, Davis TME, Karunajeewa H, Salman S, Checchi F, Fogg C, Newton PN, Mayxay M, Deloron P, Faucher JF, Nosten F, Ashley EA, McGready R, van Vugt M, Proux S, Price RN, Karbwang J, Ezzet F, Bakshi R, Stepniewska K, White NJ, Guerin PJ, Barnes KI, Tarning J. Kloprogge F, et al. PLoS Med. 2018 Jun 12;15(6):e1002579. doi: 10.1371/journal.pmed.1002579. eCollection 2018 Jun. PLoS Med. 2018. PMID: 29894518 Free PMC article.
How important is gametocyte clearance after malaria therapy?
Karunajeewa HA, Mueller I. Karunajeewa HA, et al. BMC Med. 2016 Jun 18;14:93. doi: 10.1186/s12916-016-0641-3. BMC Med. 2016. PMID: 27317420 Free PMC article.
Their findings, that some ACTs clear gametocytes faster than others, should be interpreted in light of these limitations and important gaps in our understanding of the biology and epidemiology of malaria transmission.Please see related article: https://bmcmedicine.biomedce …
Their findings, that some ACTs clear gametocytes faster than others, should be interpreted in light of these limitations and important gaps …
Malaria morbidity and mortality following introduction of a universal policy of artemisinin-based treatment for malaria in Papua, Indonesia: A longitudinal surveillance study.
Kenangalem E, Poespoprodjo JR, Douglas NM, Burdam FH, Gdeumana K, Chalfein F, Prayoga, Thio F, Devine A, Marfurt J, Waramori G, Yeung S, Noviyanti R, Penttinen P, Bangs MJ, Sugiarto P, Simpson JA, Soenarto Y, Anstey NM, Price RN. Kenangalem E, et al. PLoS Med. 2019 May 29;16(5):e1002815. doi: 10.1371/journal.pmed.1002815. eCollection 2019 May. PLoS Med. 2019. PMID: 31167228 Free PMC article.
In coendemic regions, the timely elimination of malaria will require that safe and effective radical cure of both the blood and liver stages of the parasite is widely available for all patients at risk of malaria....
In coendemic regions, the timely elimination of malaria will require that safe and effective radical cure of both the blood and liver …
Effect of NO inhalation on ECMO use rate and mortality in infants born at or near term with respiratory failure.
Wang X, Li B, Ma Y, Zhang H. Wang X, et al. Medicine (Baltimore). 2019 Oct;98(41):e17139. doi: 10.1097/MD.0000000000017139. Medicine (Baltimore). 2019. PMID: 31593077 Free PMC article.
METHODS: The strategies used to search PubMed, The Cochrane Central Register of Controlled trials in the Cochrane Library, Embase, Web of science, Clinical Trials Registry, and China Biology Medicine disc, from inception to February, 2018. The primary outcomes were death o …
METHODS: The strategies used to search PubMed, The Cochrane Central Register of Controlled trials in the Cochrane Library, Embase, Web of sc …
The risk of Plasmodium vivax parasitaemia after P. falciparum malaria: An individual patient data meta-analysis from the WorldWide Antimalarial Resistance Network.
Hossain MS, Commons RJ, Douglas NM, Thriemer K, Alemayehu BH, Amaratunga C, Anvikar AR, Ashley EA, Asih PBS, Carrara VI, Lon C, D'Alessandro U, Davis TME, Dondorp AM, Edstein MD, Fairhurst RM, Ferreira MU, Hwang J, Janssens B, Karunajeewa H, Kiechel JR, Ladeia-Andrade S, Laman M, Mayxay M, McGready R, Moore BR, Mueller I, Newton PN, Thuy-Nhien NT, Noedl H, Nosten F, Phyo AP, Poespoprodjo JR, Saunders DL, Smithuis F, Spring MD, Stepniewska K, Suon S, Suputtamongkol Y, Syafruddin D, Tran HT, Valecha N, Van Herp M, Van Vugt M, White NJ, Guerin PJ, Simpson JA, Price RN. Hossain MS, et al. PLoS Med. 2020 Nov 19;17(11):e1003393. doi: 10.1371/journal.pmed.1003393. eCollection 2020 Nov. PLoS Med. 2020. PMID: 33211712 Free PMC article.
Our study aimed to quantify this risk and the associated determinants using an individual patient data meta-analysis in order to identify populations in which a policy of universal radical cure, combining artemisinin-based combination therapy (ACT) with a hypnozoitocidal a …
Our study aimed to quantify this risk and the associated determinants using an individual patient data meta-analysis in order to identify po …
A cluster randomised controlled trial of two rounds of mass drug administration in Zanzibar, a malaria pre-elimination setting-high coverage and safety, but no significant impact on transmission.
Morris U, Msellem MI, Mkali H, Islam A, Aydin-Schmidt B, Jovel I, Shija SJ, Khamis M, Ali SM, Hodzic L, Magnusson E, Poirot E, Bennett A, Sachs MC, Tarning J, Mårtensson A, Ali AS, Björkman A. Morris U, et al. BMC Med. 2018 Dec 10;16(1):215. doi: 10.1186/s12916-018-1202-8. BMC Med. 2018. PMID: 30526588 Free PMC article. Clinical Trial.
Low serum levels of uric acid and albumin in patients with Guillain-Barre syndrome.
Su Z, Chen Z, Xiang Y, Wang B, Huang Y, Yang D, Li X, Weng Y, Lin X, Chen G, Liu W, Zhao C, Wang Q, Li S, Chen Y, Chen Y, Quan W, Tong Q, Wu S, Huang S, Mei P, Li Z, Li J, Hou S, Zhang X. Su Z, et al. Medicine (Baltimore). 2017 Apr;96(15):e6618. doi: 10.1097/MD.0000000000006618. Medicine (Baltimore). 2017. PMID: 28403109 Free PMC article.
Free radical toxicity due to poorly maintained cellular redox levels is crucial events that have been associated with the pathogenesis of Guillain-Barre syndrome (GBS) patients. ...
Free radical toxicity due to poorly maintained cellular redox levels is crucial events that have been associated with the path
Role of heme in lung bacterial infection after trauma hemorrhage and stored red blood cell transfusion: A preclinical experimental study.
Wagener BM, Hu PJ, Oh JY, Evans CA, Richter JR, Honavar J, Brandon AP, Creighton J, Stephens SW, Morgan C, Dull RO, Marques MB, Kerby JD, Pittet JF, Patel RP. Wagener BM, et al. PLoS Med. 2018 Mar 9;15(3):e1002522. doi: 10.1371/journal.pmed.1002522. eCollection 2018 Mar. PLoS Med. 2018. PMID: 29522519 Free PMC article.
The mechanism underlying this increased infection susceptibility and severity was free-heme-dependent, as recombinant hemopexin or pharmacological inhibition or genetic deletion of toll-like receptor 4 (TLR4) during TH and resuscitation completely prevented P. aeruginosa-i …
The mechanism underlying this increased infection susceptibility and severity was free-heme-dependent, as recombinant hemopexin or ph …
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