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Fam151b, the mouse homologue of C.elegans menorin gene, is essential for retinal function.
Findlay AS, McKie L, Keighren M, Clementson-Mobbs S, Sanchez-Pulido L, Wells S, Cross SH, Jackson IJ. Findlay AS, et al. Sci Rep. 2020 Jan 16;10(1):437. doi: 10.1038/s41598-019-57398-4. Sci Rep. 2020. PMID: 31949211 Free PMC article.
Fam151b is a mammalian homologue of the C. elegans menorin gene, which is involved in neuronal branching. ...Histological analysis shows that during development of the eye the correct number of cells are produced and that the layers of the retina differentiate normally. Ho …
Fam151b is a mammalian homologue of the C. elegans menorin gene, which is involved in neuronal branching. ...Histological analysis sh …
A novel lncRNA FAM151B-DT regulates autophagy and degradation of aggregation prone proteins.
Renganathan A, Minaya MA, Broder M, Alfradique-Dunham I, Moritz M, Bhagat R, Marsh J, Verbeck A, Galasso G, Starr E, Agard DA, Cruchaga C, Karch CM. Renganathan A, et al. medRxiv [Preprint]. 2025 Jan 24:2025.01.22.25320997. doi: 10.1101/2025.01.22.25320997. medRxiv. 2025. PMID: 39974060 Free PMC article. Preprint.
We show that silencing FAM151B-DT in vitro is sufficient to enhance tau aggregation. To begin to understand the mechanism by which FAM151B-DT mediates tau aggregation and contributes to several neurodegenerative diseases, we deeply characterized this novel lncRNA an …
We show that silencing FAM151B-DT in vitro is sufficient to enhance tau aggregation. To begin to understand the mechanism by which …
Dynamic genomic changes in methotrexate-resistant human cancer cell lines beyond DHFR amplification suggest potential new targets for preventing drug resistance.
Meng XN, Ma JF, Liu YH, Li SQ, Wang X, Zhu J, Cai MD, Zhang HS, Song T, Xing S, Hou LQ, Guo H, Cui XB, Han J, Liu P, Ji GH, Sun WJ, Yu JC, Fu SB. Meng XN, et al. Br J Cancer. 2024 May;130(11):1819-1827. doi: 10.1038/s41416-024-02664-0. Epub 2024 Apr 9. Br J Cancer. 2024. PMID: 38594370 Free PMC article.
In the late phase (ecDNA), increase in FAM151B protein level may also have an important role by decreasing sensitivity to MTX. ...
In the late phase (ecDNA), increase in FAM151B protein level may also have an important role by decreasing sensitivity to MTX. ...
Identification of genes whose expression is altered by obesity throughout the arterial tree.
Padilla J, Jenkins NT, Thorne PK, Martin JS, Rector RS, Davis JW, Laughlin MH. Padilla J, et al. Physiol Genomics. 2014 Nov 15;46(22):821-32. doi: 10.1152/physiolgenomics.00091.2014. Epub 2014 Sep 30. Physiol Genomics. 2014. PMID: 25271210 Free PMC article.
We found a total of 15 genes that were consistently upregulated with obesity (MIS18A, CTRB1, FAM151B, FOLR2, PXMP4, OAS1B, SREBF2, KLRA17, SLC25A44, SNX10, SLFN3, MEF2BNB, IRF7, RAD23A, LGALS3BP) and five genes that were consistently downregulated with obesity (C2, GOLGA7, …
We found a total of 15 genes that were consistently upregulated with obesity (MIS18A, CTRB1, FAM151B, FOLR2, PXMP4, OAS1B, SREBF2, KL …