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Page 1
Identification of FAM181A and FAM181B as new interactors with the TEAD transcription factors.
Bokhovchuk F, Mesrouze Y, Delaunay C, Martin T, Villard F, Meyerhofer M, Fontana P, Zimmermann C, Erdmann D, Furet P, Scheufler C, Schmelzle T, Chène P. Bokhovchuk F, et al. Protein Sci. 2020 Feb;29(2):509-520. doi: 10.1002/pro.3775. Epub 2019 Nov 20. Protein Sci. 2020. PMID: 31697419 Free PMC article.
In this article, combining structural data and motif searches in protein databases, we identify two new TEAD interactors: FAM181A and FAM181B. Our structural data show that they bind to TEAD via an omega-loop as YAP/TAZ do, but only FAM181B possesses the LxxLF motif …
In this article, combining structural data and motif searches in protein databases, we identify two new TEAD interactors: FAM181A and FAM …
Analysis of the Fam181 gene family during mouse development reveals distinct strain-specific expression patterns, suggesting a role in nervous system development and function.
Marks M, Pennimpede T, Lange L, Grote P, Herrmann BG, Wittler L. Marks M, et al. Gene. 2016 Jan 10;575(2 Pt 2):438-451. doi: 10.1016/j.gene.2015.09.035. Epub 2015 Sep 25. Gene. 2016. PMID: 26407640
Here we describe the expression of Fam181b and Fam181a during murine embryonic development. In addition, we confirm oscillation of Fam181b in the psm in-phase with targets of, and regulated by, Notch signaling. Fam181b expression in the psm, as well as in the …
Here we describe the expression of Fam181b and Fam181a during murine embryonic development. In addition, we confirm oscillation of …
Genome-wide association study of body weight in Wenshang Barred chicken based on the SLAF-seq technology.
Li F, Han H, Lei Q, Gao J, Liu J, Liu W, Zhou Y, Li H, Cao D. Li F, et al. J Appl Genet. 2018 Aug;59(3):305-312. doi: 10.1007/s13353-018-0452-7. Epub 2018 Jun 27. J Appl Genet. 2018. PMID: 29946990 Review.
These SNPs are close to seven genes (PRSS23, ME3, FAM181B, NABP1, SDPR, TSSK6L2, and RBBP8). Moreover, 24 BW-associated SNPs reached "suggestive" genome-wide significance. ...
These SNPs are close to seven genes (PRSS23, ME3, FAM181B, NABP1, SDPR, TSSK6L2, and RBBP8). Moreover, 24 BW-associated SNPs reached …
Morphological Observation and Transcriptome Analysis of Ciliogenesis in Urechis unicinctus (Annelida, Echiura).
Kong D, Wei M, Liu D, Zhang Z, Ma Y, Zhang Z. Kong D, et al. Int J Mol Sci. 2023 Jul 16;24(14):11537. doi: 10.3390/ijms241411537. Int J Mol Sci. 2023. PMID: 37511295 Free PMC article.
The top 10 hub genes in the above three modules were identified to be highly correlated with ciliogenesis, including the reported cilium-related gene Cnbd2 and unreported cilium-related candidate genes FAM181B, Capsl, Chst3, TMIE and Innexin. Notably, Innexin was included …
The top 10 hub genes in the above three modules were identified to be highly correlated with ciliogenesis, including the reported cilium-rel …
GRK5 as a Novel Therapeutic Target for Immune Evasion in Testicular Cancer: Insights from Multi-Omics Analysis and Immunotherapeutic Validation.
Xu C, Zhong Q, Yu N, Zhang X, Yang K, Liu H, Cai M, Zheng Y. Xu C, et al. Biomedicines. 2025 Jul 21;13(7):1775. doi: 10.3390/biomedicines13071775. Biomedicines. 2025. PMID: 40722845 Free PMC article.
Results: Following systematic screening of five candidate genes (WNT11, FAM181B, GRK5, FSCN1, and ECHS1), GRK5 emerged as a promising therapeutic target for immunotherapy based on its distinct functional and molecular associations with immune evasion mechanisms. ...
Results: Following systematic screening of five candidate genes (WNT11, FAM181B, GRK5, FSCN1, and ECHS1), GRK5 emerged as a promising …
Association of frequent hypermethylation with high grade histological subtype in lung adenocarcinoma.
Ito Y, Usui G, Seki M, Fukuyo M, Matsusaka K, Hoshii T, Sata Y, Morimoto J, Hata A, Nakajima T, Rahmutulla B, Kaiho T, Inage T, Tanaka K, Sakairi Y, Suzuki H, Yoshino I, Kaneda A. Ito Y, et al. Cancer Sci. 2023 Jul;114(7):3003-3013. doi: 10.1111/cas.15817. Epub 2023 Apr 21. Cancer Sci. 2023. PMID: 37082886 Free PMC article.
We extracted surrogate markers for each epigenotype and designed pyrosequencing primers for five HME markers (TCERG1L, CXCL12, FAM181B, HOXA11, GAD2), three IME markers (TBX18, ZNF154, NWD2) and three Common markers (SCT, GJD2, BARHL2). ...
We extracted surrogate markers for each epigenotype and designed pyrosequencing primers for five HME markers (TCERG1L, CXCL12, FAM181B …
Knockout of the family with sequence similarity 181, member A (Fam181a) gene does not impair spermatogenesis or male fertility in the mouse.
Shah W, Khan R, Shah B, Dil S, Shi Q. Shah W, et al. Reprod Fertil Dev. 2021 Jul;33:674-681. doi: 10.1071/RD21150. Reprod Fertil Dev. 2021. PMID: 34253288
Family with sequence similarity 181 (Fam181 ) is a gene family with two paralogues (Fam181a and Fam181b ) found among vertebrates. Fam181a exhibits dynamic and stage-specific expression during murine embryo development. ...
Family with sequence similarity 181 (Fam181 ) is a gene family with two paralogues (Fam181a and Fam181b ) found among vertebrates. Fa …