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Page 1
Loss of endothelial CFTR drives barrier failure and edema formation in lung infection and can be targeted by CFTR potentiation.
Erfinanda L, Zou L, Gutbier B, Kneller L, Weidenfeld S, Michalick L, Lei D, Reppe K, Teixeira Alves LG, Schneider B, Zhang Q, Li C, Fatykhova D, Schneider P, Liedtke W, Sohara E, Mitchell TJ, Gruber AD, Hocke A, Hippenstiel S, Suttorp N, Olschewski A, Mall MA, Witzenrath M, Kuebler WM. Erfinanda L, et al. Among authors: fatykhova d. Sci Transl Med. 2022 Dec 7;14(674):eabg8577. doi: 10.1126/scitranslmed.abg8577. Epub 2022 Dec 7. Sci Transl Med. 2022. PMID: 36475904
Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages.
Hönzke K, Obermayer B, Mache C, Fatykhova D, Kessler M, Dökel S, Wyler E, Baumgardt M, Löwa A, Hoffmann K, Graff P, Schulze J, Mieth M, Hellwig K, Demir Z, Biere B, Brunotte L, Mecate-Zambrano A, Bushe J, Dohmen M, Hinze C, Elezkurtaj S, Tönnies M, Bauer TT, Eggeling S, Tran HL, Schneider P, Neudecker J, Rückert JC, Schmidt-Ott KM, Busch J, Klauschen F, Horst D, Radbruch H, Radke J, Heppner F, Corman VM, Niemeyer D, Müller MA, Goffinet C, Mothes R, Pascual-Reguant A, Hauser AE, Beule D, Landthaler M, Ludwig S, Suttorp N, Witzenrath M, Gruber AD, Drosten C, Sander LE, Wolff T, Hippenstiel S, Hocke AC. Hönzke K, et al. Among authors: fatykhova d. Eur Respir J. 2022 Dec 1;60(6):2102725. doi: 10.1183/13993003.02725-2021. Print 2022 Dec. Eur Respir J. 2022. PMID: 35728978 Free PMC article.
Human alveolar progenitors generate dual lineage bronchioalveolar organoids.
Hoffmann K, Obermayer B, Hönzke K, Fatykhova D, Demir Z, Löwa A, Alves LGT, Wyler E, Lopez-Rodriguez E, Mieth M, Baumgardt M, Hoppe J, Firsching TC, Tönnies M, Bauer TT, Eggeling S, Tran HL, Schneider P, Neudecker J, Rückert JC, Gruber AD, Ochs M, Landthaler M, Beule D, Suttorp N, Hippenstiel S, Hocke AC, Kessler M. Hoffmann K, et al. Among authors: fatykhova d. Commun Biol. 2022 Aug 25;5(1):875. doi: 10.1038/s42003-022-03828-5. Commun Biol. 2022. PMID: 36008580 Free PMC article.
The unremarkable alveolar epithelial glycocalyx: a thorium dioxide-based electron microscopic comparison after heparinase or pneumolysin treatment.
Timm S, Lettau M, Hegermann J, Rocha ML, Weidenfeld S, Fatykhova D, Gutbier B, Nouailles G, Lopez-Rodriguez E, Hocke A, Hippenstiel S, Witzenrath M, Kuebler WM, Ochs M. Timm S, et al. Among authors: fatykhova d. Histochem Cell Biol. 2023 Aug;160(2):83-96. doi: 10.1007/s00418-023-02211-7. Epub 2023 Jun 29. Histochem Cell Biol. 2023. PMID: 37386200 Free PMC article.
State-of-the-art analytical methods of viral infections in human lung organoids.
Baumgardt M, Hülsemann M, Löwa A, Fatykhova D, Hoffmann K, Kessler M, Mieth M, Hellwig K, Frey D, Langenhagen A, Voss A, Obermayer B, Wyler E, Dökel S, Gruber AD, Tölch U, Hippenstiel S, Hocke AC, Hönzke K. Baumgardt M, et al. Among authors: fatykhova d. PLoS One. 2022 Dec 20;17(12):e0276115. doi: 10.1371/journal.pone.0276115. eCollection 2022. PLoS One. 2022. PMID: 36538516 Free PMC article.
Ex vivo infection model for Francisella using human lung tissue.
Köppen K, Fatykhova D, Holland G, Rauch J, Tappe D, Graff M, Rydzewski K, Hocke AC, Hippenstiel S, Heuner K. Köppen K, et al. Among authors: fatykhova d. Front Cell Infect Microbiol. 2023 Jul 10;13:1224356. doi: 10.3389/fcimb.2023.1224356. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 37492528 Free PMC article.
Pneumolysin induced mitochondrial dysfunction leads to release of mitochondrial DNA.
Nerlich A, Mieth M, Letsiou E, Fatykhova D, Zscheppang K, Imai-Matsushima A, Meyer TF, Paasch L, Mitchell TJ, Tönnies M, Bauer TT, Schneider P, Neudecker J, Rückert JC, Eggeling S, Schimek M, Witzenrath M, Suttorp N, Hippenstiel S, Hocke AC. Nerlich A, et al. Among authors: fatykhova d. Sci Rep. 2018 Jan 9;8(1):182. doi: 10.1038/s41598-017-18468-7. Sci Rep. 2018. PMID: 29317705 Free PMC article.
Correction: State-of-the-art analytical methods of viral infections in human lung organoids.
Baumgardt M, Hülsemann M, Löwa A, Fatykhova D, Hoffmann K, Kessler M, Mieth M, Hellwig K, Frey D, Langenhagen A, Voss A, Obermayer B, Wyler E, Dökel S, Gruber AD, Tölch U, Hippenstiel S, Hocke AC, Hönzke K. Baumgardt M, et al. Among authors: fatykhova d. PLoS One. 2023 Nov 3;18(11):e0294216. doi: 10.1371/journal.pone.0294216. eCollection 2023. PLoS One. 2023. PMID: 37922305 Free PMC article.
Functional comparison of MERS-coronavirus lineages reveals increased replicative fitness of the recombinant lineage 5.
Schroeder S, Mache C, Kleine-Weber H, Corman VM, Muth D, Richter A, Fatykhova D, Memish ZA, Stanifer ML, Boulant S, Gultom M, Dijkman R, Eggeling S, Hocke A, Hippenstiel S, Thiel V, Pöhlmann S, Wolff T, Müller MA, Drosten C. Schroeder S, et al. Among authors: fatykhova d. Nat Commun. 2021 Sep 7;12(1):5324. doi: 10.1038/s41467-021-25519-1. Nat Commun. 2021. PMID: 34493730 Free PMC article.
16 results