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Year Number of Results
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153 results

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Page 1
FCGBP promotes ovarian cancer progression via activation of IL-6/JAK-STAT signaling pathway.
Fu Z, Chen K, Zheng F, Gong W, Chao D, Lu C. Fu Z, et al. J Transl Med. 2025 Jul 25;23(1):827. doi: 10.1186/s12967-025-06854-z. J Transl Med. 2025. PMID: 40713656 Free PMC article.
Weighted gene co-expression network analysis was performed to correlate FCGBP expression with clinical traits. Single-cell RNA sequencing and pseudotime trajectory analyses were used to examine FCGBP expression dynamics. ...Single-cell analysis showed FCGBP e …
Weighted gene co-expression network analysis was performed to correlate FCGBP expression with clinical traits. Single-cell RNA sequen …
Role of the mucin-like glycoprotein FCGBP in mucosal immunity and cancer.
Liu Q, Niu X, Li Y, Zhang JR, Zhu SJ, Yang QY, Zhang W, Gong L. Liu Q, et al. Front Immunol. 2022 Jul 22;13:863317. doi: 10.3389/fimmu.2022.863317. eCollection 2022. Front Immunol. 2022. PMID: 35936008 Free PMC article. Review.
FCGBP forms disulfide-linked heterodimers with mucin-2 and members of the trefoil factor family. ...FCGBP is also involved in regulating the infiltration of immune cells into tumor microenvironments. ...
FCGBP forms disulfide-linked heterodimers with mucin-2 and members of the trefoil factor family. ...FCGBP is also involved in …
FCGBP Is a Prognostic Biomarker and Associated With Immune Infiltration in Glioma.
Yan T, Tian D, Chen J, Tan Y, Cheng Y, Ye L, Deng G, Liu B, Yuan F, Zhang S, Cai L, Chen Q. Yan T, et al. Front Oncol. 2022 Jan 3;11:769033. doi: 10.3389/fonc.2021.769033. eCollection 2021. Front Oncol. 2022. PMID: 35047393 Free PMC article.
The Fc Fragment of IgG Binding Protein (FCGBP) has been proven to participate in intestinal tumor immunity. However, the biological role of FCGBP has remained unclear in glioma. The differential expression of FCGBP was explored by Oncomine and GEPIA databases …
The Fc Fragment of IgG Binding Protein (FCGBP) has been proven to participate in intestinal tumor immunity. However, the biological r …
FCGBP Is a Promising Prognostic Biomarker and Correlates with Immunotherapy Efficacy in Oral Squamous Cell Carcinoma.
Shen T, Zhang J, Wang Y, Liu B. Shen T, et al. J Immunol Res. 2022 Jun 12;2022:8443392. doi: 10.1155/2022/8443392. eCollection 2022. J Immunol Res. 2022. PMID: 35733916 Free PMC article.
In this research, we aimed to study the expressions and prognostic values of IgG Fc binding protein (FCGBP) in OSCC patients. The expression of FCGBP was analyzed using TCGA datasets and GEO datasets. ...In addition, researchers looked into the relationships between …
In this research, we aimed to study the expressions and prognostic values of IgG Fc binding protein (FCGBP) in OSCC patients. The exp …
FCGBP functions as a tumor suppressor gene in head and neck squamous cell carcinoma.
Zeng L, Zeng J, He J, Li Y, Li C, Lin Z, Chen G, Wu H, Zhou L. Zeng L, et al. Discov Oncol. 2024 Nov 24;15(1):704. doi: 10.1007/s12672-024-01607-8. Discov Oncol. 2024. PMID: 39580769 Free PMC article.
Genes co-expressed with FCGBP were mainly enriched in immune-related biological processes and pathways. GSEA indicated that FCGBP was associated with activated immune reaction and inhibiting well-known pro-tumor pathways. GSE41613 validated FCGBP as an indepe …
Genes co-expressed with FCGBP were mainly enriched in immune-related biological processes and pathways. GSEA indicated that FCGBP …
Revealing the role of necroptosis microenvironment: FCGBP + tumor-associated macrophages drive primary liver cancer differentiation towards cHCC-CCA or iCCA.
Wang C, Chen C, Hu W, Tao L, Chen J. Wang C, et al. Apoptosis. 2024 Apr;29(3-4):460-481. doi: 10.1007/s10495-023-01908-3. Epub 2023 Nov 28. Apoptosis. 2024. PMID: 38017206
ScRNA-seq analysis of HCC and iCCA revealed that necroptosis predominantly occurred in the myeloid cell subset, particularly in FCGBP + SPP1 + tumor-associated macrophages (TAMs), which had the highest likelihood of undergoing necroptosis. ...The emergence of necroptosis m …
ScRNA-seq analysis of HCC and iCCA revealed that necroptosis predominantly occurred in the myeloid cell subset, particularly in FCGBP …
FcGBP and VCAM-1 are ponderable biomarkers for differential diagnosis of alcoholic liver cirrhosis.
Abassa KK, Xiao XP, Zhou HX, Wu XY, Guo YW, Wu B. Abassa KK, et al. Drug Alcohol Depend. 2022 Apr 1;233:109377. doi: 10.1016/j.drugalcdep.2022.109377. Epub 2022 Feb 24. Drug Alcohol Depend. 2022. PMID: 35245761
RESULTS: 452 cirrhotic and normal subjects were enrolled in this study. The proteomic results revealed that FcGBP and VCAM-1 were the highest overexpressed proteins while comparing ALD samples to the healthy cohort. ...The discrimination performance of this combination was …
RESULTS: 452 cirrhotic and normal subjects were enrolled in this study. The proteomic results revealed that FcGBP and VCAM-1 were the …
Predictive value of FCGBP expression for treatment response and survival in rectal cancer patients undergoing chemoradiotherapy.
Su YT, Chen CH, Kang JW, Kuo HY, Yang CC, Tian YF, Yeh CF, Chou CL, Chen SH. Su YT, et al. Aging (Albany NY). 2024 May 3;16(9):7889-7901. doi: 10.18632/aging.205791. Epub 2024 May 3. Aging (Albany NY). 2024. PMID: 38709264 Free PMC article.
Focusing on cell adhesion during data mining, we identified FCGBP as the most upregulated gene associated with CRT resistance. Subsequently, we assessed FCGBP immunointensity using immunohistochemical staining on 343 rectal cancer tissue blocks. ...FCGBP hold …
Focusing on cell adhesion during data mining, we identified FCGBP as the most upregulated gene associated with CRT resistance. Subseq …
FcGBP was upregulated by HPV infection and correlated to longer survival time of HNSCC patients.
Wang Y, Liu Y, Liu H, Zhang Q, Song H, Tang J, Fu J, Wang X. Wang Y, et al. Oncotarget. 2017 Sep 23;8(49):86503-86514. doi: 10.18632/oncotarget.21220. eCollection 2017 Oct 17. Oncotarget. 2017. PMID: 29156811 Free PMC article.
Gene expression level of FcGBP and TGF-beta was negatively correlated in HNSCC tissues. FcGBP expression level increased after HPV E6 overexpression in HPV-negative HNSCC cells, and TGF-beta could inhibit the up-regulation of FcGBP after HPV E6 or FcGBP …
Gene expression level of FcGBP and TGF-beta was negatively correlated in HNSCC tissues. FcGBP expression level increased after …
FCGBP Promotes Glioma Growth by Regulating JAK2/STAT3/c-Myc Pathway.
Zheng J, Rao YX, Zheng H, Shi LL. Zheng J, et al. Cancer Med. 2026 Feb;15(2):e71617. doi: 10.1002/cam4.71617. Cancer Med. 2026. PMID: 41692424 Free PMC article.
BACKGROUND: FCGBP has been implicated in the development of a variety of tumors, but its exact role in glioma progression remains unclear. ...Functional assays demonstrated that FCGBP promotes glioma cell aggressiveness by activating the JAK2/STAT3 signaling pathway …
BACKGROUND: FCGBP has been implicated in the development of a variety of tumors, but its exact role in glioma progression remains unc …
153 results