Fedyk ER[au] - Search Results

Year	Number of Results
1994	2
1996	3
1997	2
1999	1
2001	2
2003	1
2005	1
2006	1
2007	1
2008	1
2009	1
2010	1
2012	1
2013	1
2018	1
2019	1
2020	1
2021	1

1

The binding specificity and selective antagonism of vedolizumab, an anti-alpha4beta7 integrin therapeutic antibody in development for inflammatory bowel diseases.

Soler D, Chapman T, Yang LL, Wyant T, Egan R, Fedyk ER. Soler D, et al. Among authors: fedyk er. J Pharmacol Exp Ther. 2009 Sep;330(3):864-75. doi: 10.1124/jpet.109.153973. Epub 2009 Jun 9. J Pharmacol Exp Ther. 2009. PMID: 19509315

2

Safety, tolerability, pharmacokinetics and pharmacodynamics of the anti-CD38 cytolytic antibody TAK-079 in healthy subjects.

Fedyk ER, Zhao L, Koch A, Smithson G, Estevam J, Chen G, Lahu G, Roepcke S, Lin J, Mclean L. Fedyk ER, et al. Br J Clin Pharmacol. 2020 Jul;86(7):1314-1325. doi: 10.1111/bcp.14241. Epub 2020 Feb 22. Br J Clin Pharmacol. 2020. PMID: 32045493 Free PMC article.

3

A Reduction in B, T, and Natural Killer Cells Expressing CD38 by TAK-079 Inhibits the Induction and Progression of Collagen-Induced Arthritis in Cynomolgus Monkeys.

Korver W, Carsillo M, Yuan J, Idamakanti N, Wagoner M, Shi P, Xia CQ, Smithson G, McLean L, Zalevsky J, Fedyk ER. Korver W, et al. Among authors: fedyk er. J Pharmacol Exp Ther. 2019 Aug;370(2):182-196. doi: 10.1124/jpet.119.256602. Epub 2019 May 13. J Pharmacol Exp Ther. 2019. PMID: 31085699

4

Pharmacokinetics and pharmacodynamics of the cytolytic anti-CD38 human monoclonal antibody TAK-079 in monkey - model assisted preparation for the first in human trial.

Roepcke S, Plock N, Yuan J, Fedyk ER, Lahu G, Zhao L, Smithson G. Roepcke S, et al. Among authors: fedyk er. Pharmacol Res Perspect. 2018 Jun;6(3):e00402. doi: 10.1002/prp2.402. Epub 2018 May 17. Pharmacol Res Perspect. 2018. PMID: 29864242 Free PMC article.

5

Prostaglandin receptors of the EP2 and EP4 subtypes regulate B lymphocyte activation and differentiation to IgE-secreting cells.

Fedyk ER, Harris SG, Padilla J, Phipps RP. Fedyk ER, et al. Adv Exp Med Biol. 1997;433:153-7. doi: 10.1007/978-1-4899-1810-9_31. Adv Exp Med Biol. 1997. PMID: 9561124 Review. No abstract available.

6

Regulation of IgE and cytokine production by cAMP: implications for extrinsic asthma.

Fedyk ER, Adawi A, Looney RJ, Phipps RP. Fedyk ER, et al. Clin Immunol Immunopathol. 1996 Nov;81(2):101-13. doi: 10.1006/clin.1996.0165. Clin Immunol Immunopathol. 1996. PMID: 8906740 Review.

7

PGE2 regulation of B lymphocytes and T helper 1 and T helper 2 cells: induction of inflammatory versus allergic responses.

Fedyk ER, Brown DM, Phipps RP. Fedyk ER, et al. Adv Exp Med Biol. 1997;407:237-42. doi: 10.1007/978-1-4899-1813-0_35. Adv Exp Med Biol. 1997. PMID: 9321958 Review. No abstract available.

8

Exclusive antagonism of the α4 β7 integrin by vedolizumab confirms the gut-selectivity of this pathway in primates.

Fedyk ER, Wyant T, Yang LL, Csizmadia V, Burke K, Yang H, Kadambi VJ. Fedyk ER, et al. Inflamm Bowel Dis. 2012 Nov;18(11):2107-19. doi: 10.1002/ibd.22940. Epub 2012 Mar 14. Inflamm Bowel Dis. 2012. PMID: 22419649

9

Antagonizing the α4β1 integrin, but not α4β7, inhibits leukocytic infiltration of the central nervous system in rhesus monkey experimental autoimmune encephalomyelitis.

Haanstra KG, Hofman SO, Lopes Estêvão DM, Blezer EL, Bauer J, Yang LL, Wyant T, Csizmadia V, 't Hart BA, Fedyk ER. Haanstra KG, et al. Among authors: fedyk er. J Immunol. 2013 Mar 1;190(5):1961-73. doi: 10.4049/jimmunol.1202490. Epub 2013 Jan 30. J Immunol. 2013. PMID: 23365083 Free article.

10

Effect of proteasome inhibitors with different chemical structures on the ubiquitin-proteasome system in vitro.

Csizmadia V, Csizmadia E, Silverman L, Simpson C, Raczynski A, O'Brien L, Gallacher M, Cardoza K, Kadambi VJ, Fedyk ER, Alden CL. Csizmadia V, et al. Among authors: fedyk er. Vet Pathol. 2010 Mar;47(2):358-67. doi: 10.1177/0300985809358423. Epub 2010 Feb 1. Vet Pathol. 2010. PMID: 20124009

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