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Coronaviruses: an overview of their replication and pathogenesis.

Fehr AR, Perlman S. Fehr AR, et al. Methods Mol Biol. 2015;1282:1-23. doi: 10.1007/978-1-4939-2438-7_1. Methods Mol Biol. 2015. PMID: 25720466 Free PMC article. Review.

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β-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory Pathway.

Ghosh S, Dellibovi-Ragheb TA, Kerviel A, Pak E, Qiu Q, Fisher M, Takvorian PM, Bleck C, Hsu VW, Fehr AR, Perlman S, Achar SR, Straus MR, Whittaker GR, de Haan CAM, Kehrl J, Altan-Bonnet G, Altan-Bonnet N. Ghosh S, et al. Among authors: fehr ar. Cell. 2020 Dec 10;183(6):1520-1535.e14. doi: 10.1016/j.cell.2020.10.039. Epub 2020 Oct 27. Cell. 2020. PMID: 33157038 Free PMC article.

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ADP-ribosyltransferases, an update on function and nomenclature.

Lüscher B, Ahel I, Altmeyer M, Ashworth A, Bai P, Chang P, Cohen M, Corda D, Dantzer F, Daugherty MD, Dawson TM, Dawson VL, Deindl S, Fehr AR, Feijs KLH, Filippov DV, Gagné JP, Grimaldi G, Guettler S, Hoch NC, Hottiger MO, Korn P, Kraus WL, Ladurner A, Lehtiö L, Leung AKL, Lord CJ, Mangerich A, Matic I, Matthews J, Moldovan GL, Moss J, Natoli G, Nielsen ML, Niepel M, Nolte F, Pascal J, Paschal BM, Pawłowski K, Poirier GG, Smith S, Timinszky G, Wang ZQ, Yélamos J, Yu X, Zaja R, Ziegler M. Lüscher B, et al. Among authors: fehr ar. FEBS J. 2021 Jul 29:10.1111/febs.16142. doi: 10.1111/febs.16142. Online ahead of print. FEBS J. 2021. PMID: 34323016 Free article.

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Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity.

Heer CD, Sanderson DJ, Voth LS, Alhammad YMO, Schmidt MS, Trammell SAJ, Perlman S, Cohen MS, Fehr AR, Brenner C. Heer CD, et al. Among authors: fehr ar. J Biol Chem. 2020 Dec 25;295(52):17986-17996. doi: 10.1074/jbc.RA120.015138. Epub 2020 Oct 13. J Biol Chem. 2020. PMID: 33051211 Free PMC article.

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Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice.

Channappanavar R, Fehr AR, Vijay R, Mack M, Zhao J, Meyerholz DK, Perlman S. Channappanavar R, et al. Among authors: fehr ar. Cell Host Microbe. 2016 Feb 10;19(2):181-93. doi: 10.1016/j.chom.2016.01.007. Cell Host Microbe. 2016. PMID: 26867177 Free PMC article.

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The SARS-CoV-2 Conserved Macrodomain Is a Mono-ADP-Ribosylhydrolase.

Alhammad YMO, Kashipathy MM, Roy A, Gagné JP, McDonald P, Gao P, Nonfoux L, Battaile KP, Johnson DK, Holmstrom ED, Poirier GG, Lovell S, Fehr AR. Alhammad YMO, et al. Among authors: fehr ar. J Virol. 2021 Jan 13;95(3):e01969-20. doi: 10.1128/JVI.01969-20. Print 2021 Jan 13. J Virol. 2021. PMID: 33158944 Free PMC article.

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The Viral Macrodomain Counters Host Antiviral ADP-Ribosylation.

Alhammad YMO, Fehr AR. Alhammad YMO, et al. Among authors: fehr ar. Viruses. 2020 Mar 31;12(4):384. doi: 10.3390/v12040384. Viruses. 2020. PMID: 32244383 Free PMC article. Review.

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Viral Macrodomains: Unique Mediators of Viral Replication and Pathogenesis.

Fehr AR, Jankevicius G, Ahel I, Perlman S. Fehr AR, et al. Trends Microbiol. 2018 Jul;26(7):598-610. doi: 10.1016/j.tim.2017.11.011. Trends Microbiol. 2018. PMID: 29268982 Free PMC article. Review.

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The impact of PARPs and ADP-ribosylation on inflammation and host-pathogen interactions.

Fehr AR, Singh SA, Kerr CM, Mukai S, Higashi H, Aikawa M. Fehr AR, et al. Genes Dev. 2020 Mar 1;34(5-6):341-359. doi: 10.1101/gad.334425.119. Epub 2020 Feb 6. Genes Dev. 2020. PMID: 32029454 Free PMC article. Review.

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The SARS-CoV-2 conserved macrodomain is a mono-ADP-ribosylhydrolase.

Alhammad YMO, Kashipathy MM, Roy A, Gagné JP, McDonald P, Gao P, Nonfoux L, Battaile KP, Johnson DK, Holmstrom ED, Poirier GG, Lovell S, Fehr AR. Alhammad YMO, et al. Among authors: fehr ar. bioRxiv. 2020 Oct 28:2020.05.11.089375. doi: 10.1101/2020.05.11.089375. Preprint. bioRxiv. 2020. PMID: 32511412 Free PMC article. Updated.

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