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Parkin coregulates glutathione metabolism in adult mammalian brain.
El Kodsi DN, Tokarew JM, Sengupta R, Lengacher NA, Chatterji A, Nguyen AP, Boston H, Jiang Q, Palmberg C, Pileggi C, Holterman CE, Shutinoski B, Li J, Fehr TK, LaVoie MJ, Ratan RR, Shaw GS, Takanashi M, Hattori N, Kennedy CR, Harper ME, Holmgren A, Tomlinson JJ, Schlossmacher MG. El Kodsi DN, et al. Among authors: fehr tk. Acta Neuropathol Commun. 2023 Jan 23;11(1):19. doi: 10.1186/s40478-022-01488-4. Acta Neuropathol Commun. 2023. PMID: 36691076 Free PMC article.
Age-associated insolubility of parkin in human midbrain is linked to redox balance and sequestration of reactive dopamine metabolites.
Tokarew JM, El-Kodsi DN, Lengacher NA, Fehr TK, Nguyen AP, Shutinoski B, O'Nuallain B, Jin M, Khan JM, Ng ACH, Li J, Jiang Q, Zhang M, Wang L, Sengupta R, Barber KR, Tran A, Im DS, Callaghan S, Park DS, Zandee S, Dong X, Scherzer CR, Prat A, Tsai EC, Takanashi M, Hattori N, Chan JA, Zecca L, West AB, Holmgren A, Puente L, Shaw GS, Toth G, Woulfe JM, Taylor P, Tomlinson JJ, Schlossmacher MG. Tokarew JM, et al. Among authors: fehr tk. Acta Neuropathol. 2021 May;141(5):725-754. doi: 10.1007/s00401-021-02285-4. Epub 2021 Mar 10. Acta Neuropathol. 2021. PMID: 33694021 Free PMC article.