Ficorilli J[au] - Search Results

Year	Number of Results
1998	3
2000	1
2004	1
2005	2
2006	2
2010	2
2012	3
2013	1
2014	1
2015	1
2016	3
2017	1
2018	1
2019	1
2020	1
2021	1
2022	1

1

Structural insights into probe-dependent positive allosterism of the GLP-1 receptor.

Bueno AB, Sun B, Willard FS, Feng D, Ho JD, Wainscott DB, Showalter AD, Vieth M, Chen Q, Stutsman C, Chau B, Ficorilli J, Agejas FJ, Cumming GR, Jiménez A, Rojo I, Kobilka TS, Kobilka BK, Sloop KW. Bueno AB, et al. Among authors: ficorilli j. Nat Chem Biol. 2020 Oct;16(10):1105-1110. doi: 10.1038/s41589-020-0589-7. Epub 2020 Jul 20. Nat Chem Biol. 2020. PMID: 32690941

2

Regulation of GPR119 receptor activity with endocannabinoid-like lipids.

Syed SK, Bui HH, Beavers LS, Farb TB, Ficorilli J, Chesterfield AK, Kuo MS, Bokvist K, Barrett DG, Efanov AM. Syed SK, et al. Among authors: ficorilli j. Am J Physiol Endocrinol Metab. 2012 Dec 15;303(12):E1469-78. doi: 10.1152/ajpendo.00269.2012. Epub 2012 Oct 16. Am J Physiol Endocrinol Metab. 2012. PMID: 23074242 Free article.

3

Catechol estrogens stimulate insulin secretion in pancreatic β-cells via activation of the transient receptor potential A1 (TRPA1) channel.

Ma W, Chen X, Cerne R, Syed SK, Ficorilli JV, Cabrera O, Obukhov AG, Efanov AM. Ma W, et al. Among authors: ficorilli jv. J Biol Chem. 2019 Feb 22;294(8):2935-2946. doi: 10.1074/jbc.RA118.005504. Epub 2018 Dec 26. J Biol Chem. 2019. PMID: 30587572 Free PMC article.

4

Positive Allosteric Modulation of the Glucagon-like Peptide-1 Receptor by Diverse Electrophiles.

Bueno AB, Showalter AD, Wainscott DB, Stutsman C, Marín A, Ficorilli J, Cabrera O, Willard FS, Sloop KW. Bueno AB, et al. Among authors: ficorilli j. J Biol Chem. 2016 May 13;291(20):10700-15. doi: 10.1074/jbc.M115.696039. Epub 2016 Mar 14. J Biol Chem. 2016. PMID: 26975372 Free PMC article.

5

Allosteric modulation of endogenous metabolites as an avenue for drug discovery.

Wootten D, Savage EE, Valant C, May LT, Sloop KW, Ficorilli J, Showalter AD, Willard FS, Christopoulos A, Sexton PM. Wootten D, et al. Among authors: ficorilli j. Mol Pharmacol. 2012 Aug;82(2):281-90. doi: 10.1124/mol.112.079319. Epub 2012 May 10. Mol Pharmacol. 2012. PMID: 22576254

6

Intra-islet glucagon confers β-cell glucose competence for first-phase insulin secretion and favors GLP-1R stimulation by exogenous glucagon.

Cabrera O, Ficorilli J, Shaw J, Echeverri F, Schwede F, Chepurny OG, Leech CA, Holz GG. Cabrera O, et al. Among authors: ficorilli j. J Biol Chem. 2022 Feb;298(2):101484. doi: 10.1016/j.jbc.2021.101484. Epub 2021 Dec 9. J Biol Chem. 2022. PMID: 34896391 Free PMC article.

7

Ectonucleotidase NTPDase3 is abundant in pancreatic β-cells and regulates glucose-induced insulin secretion.

Syed SK, Kauffman AL, Beavers LS, Alston JT, Farb TB, Ficorilli J, Marcelo MC, Brenner MB, Bokvist K, Barrett DG, Efanov AM. Syed SK, et al. Among authors: ficorilli j. Am J Physiol Endocrinol Metab. 2013 Nov 15;305(10):E1319-26. doi: 10.1152/ajpendo.00328.2013. Epub 2013 Oct 1. Am J Physiol Endocrinol Metab. 2013. PMID: 24085034 Free article.

8

The Discovery, Preclinical, and Early Clinical Development of Potent and Selective GPR40 Agonists for the Treatment of Type 2 Diabetes Mellitus (LY2881835, LY2922083, and LY2922470).

Hamdouchi C, Kahl SD, Patel Lewis A, Cardona GR, Zink RW, Chen K, Eessalu TE, Ficorilli JV, Marcelo MC, Otto KA, Wilbur KL, Lineswala JP, Piper JL, Coffey DS, Sweetana SA, Haas JV, Brooks DA, Pratt EJ, Belin RM, Deeg MA, Ma X, Cannady EA, Johnson JT, Yumibe NP, Chen Q, Maiti P, Montrose-Rafizadeh C, Chen Y, Reifel Miller A. Hamdouchi C, et al. Among authors: ficorilli jv. J Med Chem. 2016 Dec 22;59(24):10891-10916. doi: 10.1021/acs.jmedchem.6b00892. Epub 2016 Nov 11. J Med Chem. 2016. PMID: 27749056

9

Regulation of Endogenous (Male) Rodent GLP-1 Secretion and Human Islet Insulin Secretion by Antagonism of Somatostatin Receptor 5.

Farb TB, Adeva M, Beauchamp TJ, Cabrera O, Coates DA, Meredith TD, Droz BA, Efanov A, Ficorilli JV, Gackenheimer SL, Martinez-Grau MA, Molero V, Ruano G, Statnick MA, Suter TM, Syed SK, Toledo MA, Willard FS, Zhou X, Bokvist KB, Barrett DG. Farb TB, et al. Among authors: ficorilli jv. Endocrinology. 2017 Nov 1;158(11):3859-3873. doi: 10.1210/en.2017-00639. Endocrinology. 2017. PMID: 28938487

10

Small molecule allosteric modulation of the glucagon-like Peptide-1 receptor enhances the insulinotropic effect of oxyntomodulin.

Willard FS, Wootten D, Showalter AD, Savage EE, Ficorilli J, Farb TB, Bokvist K, Alsina-Fernandez J, Furness SG, Christopoulos A, Sexton PM, Sloop KW. Willard FS, et al. Among authors: ficorilli j. Mol Pharmacol. 2012 Dec;82(6):1066-73. doi: 10.1124/mol.112.080432. Epub 2012 Aug 28. Mol Pharmacol. 2012. PMID: 22930710

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