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Inhaled 45-50% argon augments hypothermic brain protection in a piglet model of perinatal asphyxia.
Broad KD, Fierens I, Fleiss B, Rocha-Ferreira E, Ezzati M, Hassell J, Alonso-Alconada D, Bainbridge A, Kawano G, Ma D, Tachtsidis I, Gressens P, Golay X, Sanders RD, Robertson NJ. Broad KD, et al. Among authors: fierens i. Neurobiol Dis. 2016 Mar;87:29-38. doi: 10.1016/j.nbd.2015.12.001. Epub 2015 Dec 10. Neurobiol Dis. 2016. PMID: 26687546 Free PMC article.
Dexmedetomidine Combined with Therapeutic Hypothermia Is Associated with Cardiovascular Instability and Neurotoxicity in a Piglet Model of Perinatal Asphyxia.
Ezzati M, Kawano G, Rocha-Ferreira E, Alonso-Alconada D, Hassell JK, Broad KD, Fierens I, Fleiss B, Bainbridge A, Price DL, Kaynezhad P, Anderson B, Hristova M, Tachtsidis I, Golay X, Gressens P, Sanders RD, Robertson NJ. Ezzati M, et al. Among authors: fierens i. Dev Neurosci. 2017;39(1-4):156-170. doi: 10.1159/000458438. Epub 2017 Apr 8. Dev Neurosci. 2017. PMID: 28391258
Immediate remote ischemic postconditioning after hypoxia ischemia in piglets protects cerebral white matter but not grey matter.
Ezzati M, Bainbridge A, Broad KD, Kawano G, Oliver-Taylor A, Rocha-Ferreira E, Alonso-Alconada D, Fierens I, Rostami J, Jane Hassell K, Tachtsidis I, Gressens P, Hristova M, Bennett K, Lebon S, Fleiss B, Yellon D, Hausenloy DJ, Golay X, Robertson NJ. Ezzati M, et al. Among authors: fierens i. J Cereb Blood Flow Metab. 2016 Aug;36(8):1396-411. doi: 10.1177/0271678X15608862. Epub 2015 Oct 8. J Cereb Blood Flow Metab. 2016. PMID: 26661194 Free PMC article.
Isoflurane Exposure Induces Cell Death, Microglial Activation and Modifies the Expression of Genes Supporting Neurodevelopment and Cognitive Function in the Male Newborn Piglet Brain.
Broad KD, Hassell J, Fleiss B, Kawano G, Ezzati M, Rocha-Ferreira E, Hristova M, Bennett K, Fierens I, Burnett R, Chaban B, Alonso-Alconada D, Oliver-Taylor A, Tachsidis I, Rostami J, Gressens P, Sanders RD, Robertson NJ. Broad KD, et al. Among authors: fierens i. PLoS One. 2016 Nov 29;11(11):e0166784. doi: 10.1371/journal.pone.0166784. eCollection 2016. PLoS One. 2016. PMID: 27898690 Free PMC article.
Surgery increases cell death and induces changes in gene expression compared with anesthesia alone in the developing piglet brain.
Broad KD, Kawano G, Fierens I, Rocha-Ferreira E, Hristova M, Ezzati M, Rostami J, Alonso-Alconada D, Chaban B, Hassell J, Fleiss B, Gressens P, Sanders RD, Robertson NJ. Broad KD, et al. Among authors: fierens i. PLoS One. 2017 Mar 29;12(3):e0173413. doi: 10.1371/journal.pone.0173413. eCollection 2017. PLoS One. 2017. PMID: 28355229 Free PMC article.