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LRRC8A homohexameric channels poorly recapitulate VRAC regulation and pharmacology.

Yamada T, Figueroa EE, Denton JS, Strange K. Yamada T, et al. Among authors: figueroa ee. Am J Physiol Cell Physiol. 2021 Mar 1;320(3):C293-C303. doi: 10.1152/ajpcell.00454.2020. Epub 2020 Dec 23. Am J Physiol Cell Physiol. 2021. PMID: 33356947 Free PMC article.

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Zinc pyrithione activates the volume-regulated anion channel through an antioxidant-sensitive mechanism.

Figueroa EE, Denton JS. Figueroa EE, et al. Am J Physiol Cell Physiol. 2021 Jun 1;320(6):C1088-C1098. doi: 10.1152/ajpcell.00070.2021. Epub 2021 Apr 7. Am J Physiol Cell Physiol. 2021. PMID: 33826406 Free PMC article.

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A SWELL time to develop the molecular pharmacology of the volume-regulated anion channel (VRAC).

Figueroa EE, Denton JS. Figueroa EE, et al. Channels (Austin). 2022 Dec;16(1):27-36. doi: 10.1080/19336950.2022.2033511. Channels (Austin). 2022. PMID: 35114895 Free PMC article. Review.

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The LRRC8 volume-regulated anion channel inhibitor, DCPIB, inhibits mitochondrial respiration independently of the channel.

Afzal A, Figueroa EE, Kharade SV, Bittman K, Matlock BK, Flaherty DK, Denton JS. Afzal A, et al. Among authors: figueroa ee. Physiol Rep. 2019 Dec;7(23):e14303. doi: 10.14814/phy2.14303. Physiol Rep. 2019. PMID: 31814333 Free PMC article.

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CysLT1 receptor antagonists pranlukast and zafirlukast inhibit LRRC8-mediated volume regulated anion channels independently of the receptor.

Figueroa EE, Kramer M, Strange K, Denton JS. Figueroa EE, et al. Am J Physiol Cell Physiol. 2019 Oct 1;317(4):C857-C866. doi: 10.1152/ajpcell.00281.2019. Epub 2019 Aug 7. Am J Physiol Cell Physiol. 2019. PMID: 31390227 Free PMC article.

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ML418: The First Selective, Sub-Micromolar Pore Blocker of Kir7.1 Potassium Channels.

Swale DR, Kurata H, Kharade SV, Sheehan J, Raphemot R, Voigtritter KR, Figueroa EE, Meiler J, Blobaum AL, Lindsley CW, Hopkins CR, Denton JS. Swale DR, et al. Among authors: figueroa ee. ACS Chem Neurosci. 2016 Jul 20;7(7):1013-23. doi: 10.1021/acschemneuro.6b00111. Epub 2016 May 24. ACS Chem Neurosci. 2016. PMID: 27184474 Free PMC article.

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Discovery, Characterization, and Effects on Renal Fluid and Electrolyte Excretion of the Kir4.1 Potassium Channel Pore Blocker, VU0134992.

Kharade SV, Kurata H, Bender AM, Blobaum AL, Figueroa EE, Duran A, Kramer M, Days E, Vinson P, Flores D, Satlin LM, Meiler J, Weaver CD, Lindsley CW, Hopkins CR, Denton JS. Kharade SV, et al. Among authors: figueroa ee. Mol Pharmacol. 2018 Aug;94(2):926-937. doi: 10.1124/mol.118.112359. Epub 2018 Jun 12. Mol Pharmacol. 2018. PMID: 29895592 Free PMC article.

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Pore Polarity and Charge Determine Differential Block of Kir1.1 and Kir7.1 Potassium Channels by Small-Molecule Inhibitor VU590.

Kharade SV, Sheehan JH, Figueroa EE, Meiler J, Denton JS. Kharade SV, et al. Among authors: figueroa ee. Mol Pharmacol. 2017 Sep;92(3):338-346. doi: 10.1124/mol.117.108472. Epub 2017 Jun 15. Mol Pharmacol. 2017. PMID: 28619748 Free PMC article.

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Images in cardiovascular medicine. Infected dual-chamber pacemaker leads.

Lee MB, Iyer RS, Figueroa EE. Lee MB, et al. Among authors: figueroa ee. Circulation. 1998 Jun 23;97(24):2473. doi: 10.1161/01.cir.97.24.2473. Circulation. 1998. PMID: 9641701 No abstract available.

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Polymarker, HLA-DQAalpha, and D1S80 allele frequency data in Antioquia (Colombia) population.

Builes JJ, Moreno MA, Gaviria AM, Espinal C, Cuartas AE, Figueroa EE, Bravo ML. Builes JJ, et al. Among authors: figueroa ee. J Forensic Sci. 2002 Jul;47(4):902-3. J Forensic Sci. 2002. PMID: 12137006 No abstract available.

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