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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1968 1
1969 1
1978 2
1991 1
2002 2
2003 2
2005 1
2006 1
2007 3
2008 5
2009 6
2010 12
2011 7
2012 16
2013 14
2014 11
2015 10
2016 6
2017 11
2018 4
2019 6
2020 6
2021 8
2022 6
2023 7
2024 5
2025 5
2026 2

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148 results

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Page 1
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation.
Moran-Crusio K, Reavie L, Shih A, Abdel-Wahab O, Ndiaye-Lobry D, Lobry C, Figueroa ME, Vasanthakumar A, Patel J, Zhao X, Perna F, Pandey S, Madzo J, Song C, Dai Q, He C, Ibrahim S, Beran M, Zavadil J, Nimer SD, Melnick A, Godley LA, Aifantis I, Levine RL. Moran-Crusio K, et al. Among authors: figueroa me. Cancer Cell. 2011 Jul 12;20(1):11-24. doi: 10.1016/j.ccr.2011.06.001. Epub 2011 Jun 30. Cancer Cell. 2011. PMID: 21723200 Free PMC article.
Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression.
Cimmino L, Dolgalev I, Wang Y, Yoshimi A, Martin GH, Wang J, Ng V, Xia B, Witkowski MT, Mitchell-Flack M, Grillo I, Bakogianni S, Ndiaye-Lobry D, Martín MT, Guillamot M, Banh RS, Xu M, Figueroa ME, Dickins RA, Abdel-Wahab O, Park CY, Tsirigos A, Neel BG, Aifantis I. Cimmino L, et al. Among authors: figueroa me. Cell. 2017 Sep 7;170(6):1079-1095.e20. doi: 10.1016/j.cell.2017.07.032. Epub 2017 Aug 17. Cell. 2017. PMID: 28823558 Free PMC article.
Prognostic relevance of integrated genetic profiling in acute myeloid leukemia.
Patel JP, Gönen M, Figueroa ME, Fernandez H, Sun Z, Racevskis J, Van Vlierberghe P, Dolgalev I, Thomas S, Aminova O, Huberman K, Cheng J, Viale A, Socci ND, Heguy A, Cherry A, Vance G, Higgins RR, Ketterling RP, Gallagher RE, Litzow M, van den Brink MR, Lazarus HM, Rowe JM, Luger S, Ferrando A, Paietta E, Tallman MS, Melnick A, Abdel-Wahab O, Levine RL. Patel JP, et al. Among authors: figueroa me. N Engl J Med. 2012 Mar 22;366(12):1079-89. doi: 10.1056/NEJMoa1112304. Epub 2012 Mar 14. N Engl J Med. 2012. PMID: 22417203 Free PMC article.
IDH mutation impairs histone demethylation and results in a block to cell differentiation.
Lu C, Ward PS, Kapoor GS, Rohle D, Turcan S, Abdel-Wahab O, Edwards CR, Khanin R, Figueroa ME, Melnick A, Wellen KE, O'Rourke DM, Berger SL, Chan TA, Levine RL, Mellinghoff IK, Thompson CB. Lu C, et al. Among authors: figueroa me. Nature. 2012 Feb 15;483(7390):474-8. doi: 10.1038/nature10860. Nature. 2012. PMID: 22343901 Free PMC article.
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation.
Figueroa ME, Abdel-Wahab O, Lu C, Ward PS, Patel J, Shih A, Li Y, Bhagwat N, Vasanthakumar A, Fernandez HF, Tallman MS, Sun Z, Wolniak K, Peeters JK, Liu W, Choe SE, Fantin VR, Paietta E, Löwenberg B, Licht JD, Godley LA, Delwel R, Valk PJ, Thompson CB, Levine RL, Melnick A. Figueroa ME, et al. Cancer Cell. 2010 Dec 14;18(6):553-67. doi: 10.1016/j.ccr.2010.11.015. Epub 2010 Dec 9. Cancer Cell. 2010. PMID: 21130701 Free PMC article.
Oxidized mC modulates synthetic lethality to PARP inhibitors for the treatment of leukemia.
Brabson JP, Leesang T, Yap YS, Wang J, Lam MQ, Fang B, Dolgalev I, Barbieri DA, Strippoli V, Bañuelos CP, Mohammad S, Lyon P, Chaudhry S, Donich D, Swirski A, Roberts E, Diaz I, Karl D, Dos Santos HG, Shiekhattar R, Neel BG, Nimer SD, Verdun RE, Bilbao D, Figueroa ME, Cimmino L. Brabson JP, et al. Among authors: figueroa me. Cell Rep. 2023 Jan 31;42(1):112027. doi: 10.1016/j.celrep.2023.112027. Epub 2023 Jan 23. Cell Rep. 2023. PMID: 36848231 Free PMC article.
Activating antiviral immune responses potentiates immune checkpoint inhibition in glioblastoma models.
Seetharam D, Chandar J, Ramsoomair CK, Desgraves JF, Alvarado Medina A, Hudson AJ, Amidei A, Castro JR, Govindarajan V, Wang S, Zhang Y, Sonabend AM, Mendez Valdez MJ, Maric D, Govindarajan V, Rivas SR, Lu VM, Tiwari R, Sharifi N, Thomas E, Alexander M, DeMarino C, Johnson K, De La Fuente MI, Alshiekh Nasany R, Noviello TMR, Ivan ME, Komotar RJ, Iavarone A, Nath A, Heiss J, Ceccarelli M, Chiappinelli KB, Figueroa ME, Bayik D, Shah AH. Seetharam D, et al. Among authors: figueroa me. J Clin Invest. 2025 Mar 17;135(6):e183745. doi: 10.1172/JCI183745. J Clin Invest. 2025. PMID: 40091830 Free PMC article.
XPO1 drives resistance to eprenetapopt and azacitidine and can be targeted in TP53-mutated myeloid malignancies.
Kruer TL, Quintana A, Newman H, Ferrall-Fairbanks M, Zhang L, McLemore A, Neupane S, Yang Q, Dankyi NA, Balasis ME, Letson C, Komrokji R, Chaudhry S, Totiger TM, Traina J, Figueroa ME, Ryder CB, Cluzeau T, Taylor J, Sallman DA, Padron E. Kruer TL, et al. Among authors: figueroa me. Blood. 2025 Oct 30;146(18):2244-2258. doi: 10.1182/blood.2025028803. Blood. 2025. PMID: 40737597
Epigenetic deregulation in myeloid malignancies.
Huang HT, Figueroa ME. Huang HT, et al. Among authors: figueroa me. Blood. 2021 Aug 26;138(8):613-624. doi: 10.1182/blood.2019004262. Blood. 2021. PMID: 34436526 Review.
148 results