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Estrogen Receptor, Inflammatory, and FOXO Transcription Factors Regulate Expression of Myasthenia Gravis-Associated Circulating microRNAs.

Fiorillo AA, Heier CR, Huang YF, Tully CB, Punga T, Punga AR. Fiorillo AA, et al. Front Immunol. 2020 Feb 21;11:151. doi: 10.3389/fimmu.2020.00151. eCollection 2020. Front Immunol. 2020. PMID: 32153563 Free PMC article.

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Multi-Omics Identifies Circulating miRNA and Protein Biomarkers for Facioscapulohumeral Dystrophy.

Heier CR, Zhang A, Nguyen NY, Tully CB, Panigrahi A, Gordish-Dressman H, Pandey SN, Guglieri M, Ryan MM, Clemens PR, Thangarajh M, Webster R, Smith EC, Connolly AM, McDonald CM, Karachunski P, Tulinius M, Harper A, Mah JK, Fiorillo AA, Chen YW, Cooperative International Neuromuscular Research Group Cinrg Investigators. Heier CR, et al. Among authors: fiorillo aa. J Pers Med. 2020 Nov 19;10(4):236. doi: 10.3390/jpm10040236. J Pers Med. 2020. PMID: 33228131 Free PMC article.

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Serum miRNAs Are Pharmacodynamic Biomarkers Associated With Therapeutic Response in Pediatric Inflammatory Bowel Disease.

Batra SK, Heier CR, Diaz-Calderon L, Tully CB, Fiorillo AA, van den Anker J, Conklin LS. Batra SK, et al. Among authors: fiorillo aa. Inflamm Bowel Dis. 2020 Sep 18;26(10):1597-1606. doi: 10.1093/ibd/izaa209. Inflamm Bowel Dis. 2020. PMID: 32793975 Free PMC article.

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Muscle Weakness in Myositis: MicroRNA-Mediated Dystrophin Reduction in a Myositis Mouse Model and Human Muscle Biopsies.

Kinder TB, Heier CR, Tully CB, Van der Muelen JH, Hoffman EP, Nagaraju K, Fiorillo AA. Kinder TB, et al. Among authors: fiorillo aa. Arthritis Rheumatol. 2020 Jul;72(7):1170-1183. doi: 10.1002/art.41215. Epub 2020 May 31. Arthritis Rheumatol. 2020. PMID: 32009304 Free PMC article.

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Vamorolone targets dual nuclear receptors to treat inflammation and dystrophic cardiomyopathy.

Heier CR, Yu Q, Fiorillo AA, Tully CB, Tucker A, Mazala DA, Uaesoontrachoon K, Srinivassane S, Damsker JM, Hoffman EP, Nagaraju K, Spurney CF. Heier CR, et al. Among authors: fiorillo aa. Life Sci Alliance. 2019 Feb 11;2(1):e201800186. doi: 10.26508/lsa.201800186. Print 2019 Feb. Life Sci Alliance. 2019. PMID: 30745312 Free PMC article.

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Morpholino-induced exon skipping stimulates cell-mediated and humoral responses to dystrophin in mdx mice.

Vila MC, Novak JS, Benny Klimek M, Li N, Morales M, Fritz AG, Edwards K, Boehler JF, Hogarth MW, Kinder TB, Zhang A, Mazala D, Fiorillo AA, Douglas B, Chen YW, van den Anker J, Lu QL, Hathout Y, Hoffman EP, Partridge TA, Nagaraju K. Vila MC, et al. Among authors: fiorillo aa. J Pathol. 2019 Jul;248(3):339-351. doi: 10.1002/path.5263. Epub 2019 Apr 16. J Pathol. 2019. PMID: 30883742 Free PMC article.

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Vamorolone, a dissociative steroidal compound, reduces collagen antibody-induced joint damage and inflammation when administered after disease onset.

Damsker JM, Cornish MR, Kanneboyina P, Kanneboyina I, Yu Q, Lipson R, Phadke A, Knoblach SM, Panchapakesan K, Morales M, Fiorillo AA, Partridge T, Nagaraju K. Damsker JM, et al. Among authors: fiorillo aa. Inflamm Res. 2019 Nov;68(11):969-980. doi: 10.1007/s00011-019-01279-z. Epub 2019 Aug 24. Inflamm Res. 2019. PMID: 31446438 Free PMC article.

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TNF-α-Induced microRNAs Control Dystrophin Expression in Becker Muscular Dystrophy.

Fiorillo AA, Heier CR, Novak JS, Tully CB, Brown KJ, Uaesoontrachoon K, Vila MC, Ngheim PP, Bello L, Kornegay JN, Angelini C, Partridge TA, Nagaraju K, Hoffman EP. Fiorillo AA, et al. Cell Rep. 2015 Sep 8;12(10):1678-90. doi: 10.1016/j.celrep.2015.07.066. Epub 2015 Aug 28. Cell Rep. 2015. PMID: 26321630 Free PMC article.

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HDAC6 Deacetylates HMGN2 to Regulate Stat5a Activity and Breast Cancer Growth.

Medler TR, Craig JM, Fiorillo AA, Feeney YB, Harrell JC, Clevenger CV. Medler TR, et al. Among authors: fiorillo aa. Mol Cancer Res. 2016 Oct;14(10):994-1008. doi: 10.1158/1541-7786.MCR-16-0109. Epub 2016 Jun 29. Mol Cancer Res. 2016. PMID: 27358110 Free PMC article.

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Muscle miRNAome shows suppression of chronic inflammatory miRNAs with both prednisone and vamorolone.

Fiorillo AA, Tully CB, Damsker JM, Nagaraju K, Hoffman EP, Heier CR. Fiorillo AA, et al. Physiol Genomics. 2018 Sep 1;50(9):735-745. doi: 10.1152/physiolgenomics.00134.2017. Epub 2018 Jun 8. Physiol Genomics. 2018. PMID: 29883261 Free PMC article.

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