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Year Number of Results
1958 1
1973 1
1976 1
1982 1
1983 4
1987 1
1988 1
1989 1
1990 1
1991 1
1992 1
1995 3
1996 2
1997 2
1998 1
1999 1
2001 1
2002 1
2003 5
2004 2
2005 7
2006 6
2007 5
2008 3
2009 6
2010 8
2011 2
2012 5
2013 5
2014 2
2015 2
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2017 3
2018 8
2019 4
2020 7
2021 10
2022 3
2023 2
2024 7
2025 6

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132 results

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Page 1
Customizable virus-like particles deliver CRISPR-Cas9 ribonucleoprotein for effective ocular neovascular and Huntington's disease gene therapy.
Ling S, Zhang X, Dai Y, Jiang Z, Zhou X, Lu S, Qian X, Liu J, Selfjord N, Satir TM, Lundin A, Touza JL, Firth M, Van Zuydam N, Bilican B, Akcakaya P, Hong J, Cai Y. Ling S, et al. Among authors: firth m. Nat Nanotechnol. 2025 Apr;20(4):543-553. doi: 10.1038/s41565-024-01851-7. Epub 2025 Feb 10. Nat Nanotechnol. 2025. PMID: 39930103 Free PMC article.
Simultaneous inhibition of DNA-PK and Polϴ improves integration efficiency and precision of genome editing.
Wimberger S, Akrap N, Firth M, Brengdahl J, Engberg S, Schwinn MK, Slater MR, Lundin A, Hsieh PP, Li S, Cerboni S, Sumner J, Bestas B, Schiffthaler B, Magnusson B, Di Castro S, Iyer P, Bohlooly-Y M, Machleidt T, Rees S, Engkvist O, Norris T, Cadogan EB, Forment JV, Šviković S, Akcakaya P, Taheri-Ghahfarokhi A, Maresca M. Wimberger S, et al. Among authors: firth m. Nat Commun. 2023 Aug 14;14(1):4761. doi: 10.1038/s41467-023-40344-4. Nat Commun. 2023. PMID: 37580318 Free PMC article.
A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivo.
Bestas B, Wimberger S, Degtev D, Madsen A, Rottner AK, Karlsson F, Naumenko S, Callahan M, Touza JL, Francescatto M, Möller CI, Badertscher L, Li S, Cerboni S, Selfjord N, Ericson E, Gordon E, Firth M, Chylinski K, Taheri-Ghahfarokhi A, Bohlooly-Y M, Snowden M, Pangalos M, Nuttall B, Akcakaya P, Sienski G, Maresca M. Bestas B, et al. Among authors: firth m. Nat Commun. 2023 Sep 6;14(1):5474. doi: 10.1038/s41467-023-41240-7. Nat Commun. 2023. PMID: 37673883 Free PMC article.
Modified pegRNAs mitigate scaffold-derived prime editing by-products.
Antoniou P, Dacquay L, Mårtensson H, Madeyski-Bengtson K, Loyd AL, Shiriaeva A, Gordon E, Mustfa S, Thom G, Hsieh PP, Šviković S, Firth M, Akrap N, Maresca M, Peterka M. Antoniou P, et al. Among authors: firth m. Nat Commun. 2025 Apr 9;16(1):3374. doi: 10.1038/s41467-025-58653-1. Nat Commun. 2025. PMID: 40204736 Free PMC article.
An aptamer-mediated base editing platform for simultaneous knockin and multiple gene knockout for allogeneic CAR-T cells generation.
Porreca I, Blassberg R, Harbottle J, Joubert B, Mielczarek O, Stombaugh J, Hemphill K, Sumner J, Pazeraitis D, Touza JL, Francescatto M, Firth M, Selmi T, Collantes JC, Strezoska Z, Taylor B, Jin S, Wiggins CM, van Brabant Smith A, Lambourne JJ. Porreca I, et al. Among authors: firth m. Mol Ther. 2024 Aug 7;32(8):2692-2710. doi: 10.1016/j.ymthe.2024.06.033. Epub 2024 Jun 26. Mol Ther. 2024. PMID: 38937969 Free PMC article.
In vivo phage display identifies novel peptides for cardiac targeting.
Ivanova A, Kohl F, González-King Garibotti H, Chalupska R, Cvjetkovic A, Firth M, Jennbacken K, Martinsson S, Silva AM, Viken I, Wang QD, Wiseman J, Dekker N. Ivanova A, et al. Among authors: firth m. Sci Rep. 2024 May 28;14(1):12177. doi: 10.1038/s41598-024-62953-9. Sci Rep. 2024. PMID: 38806609 Free PMC article.
Epigenetic modulators link mitochondrial redox homeostasis to cardiac function in a sex-dependent manner.
ElBeck Z, Hossain MB, Siga H, Oskolkov N, Karlsson F, Lindgren J, Walentinsson A, Koppenhöfer D, Jarvis R, Bürli R, Jamier T, Franssen E, Firth M, Degasperi A, Bendtsen C, Menzies RI, Streckfuss-Bömeke K, Kohlhaas M, Nickel AG, Lund LH, Maack C, Végvári Á, Betsholtz C. ElBeck Z, et al. Among authors: firth m. Nat Commun. 2024 Mar 20;15(1):2358. doi: 10.1038/s41467-024-46384-8. Nat Commun. 2024. PMID: 38509128 Free PMC article.
Author Correction: CIS is a potent checkpoint in NK cell-mediated tumor immunity.
Delconte RB, Kolesnik TB, Dagley LF, Rautela J, Shi W, Putz EM, Stannard K, Zhang JG, Teh C, Firth M, Ushiki T, Andoniou CE, Degli-Esposti MA, Sharp PP, Sanvitale CE, Infusini G, Liau NPD, Linossi EM, Burns CJ, Carotta S, Gray DHD, Seillet C, Hutchinson DS, Belz GT, Webb AI, Alexander WS, Li SS, Bullock AN, Babon JJ, Smyth MJ, Nicholson SE, Huntington ND. Delconte RB, et al. Among authors: firth m. Nat Immunol. 2024 Feb;25(2):371-372. doi: 10.1038/s41590-023-01714-8. Nat Immunol. 2024. PMID: 38087084 No abstract available.
132 results