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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 1
1977 1
1981 1
1982 3
1983 1
1984 2
1986 3
1989 7
1990 1
1991 5
1992 5
1993 6
1994 3
1995 2
1996 3
1997 1
1998 1
1999 7
2001 1
2003 3
2004 2
2006 1
2007 2
2008 2
2009 2
2010 2
2011 2
2012 1
2015 1
2016 2
2023 0
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74 results
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Page 1
Discovery and Characterization of ACT-451840: an Antimalarial Drug with a Novel Mechanism of Action.
Boss C, Aissaoui H, Amaral N, Bauer A, Bazire S, Binkert C, Brun R, Bürki C, Ciana CL, Corminboeuf O, Delahaye S, Dollinger C, Fischli C, Fischli W, Flock A, Frantz MC, Girault M, Grisostomi C, Friedli A, Heidmann B, Hinder C, Jacob G, Le Bihan A, Malrieu S, Mamzed S, Merot A, Meyer S, Peixoto S, Petit N, Siegrist R, Trollux J, Weller T, Wittlin S. Boss C, et al. Among authors: fischli w. ChemMedChem. 2016 Sep 20;11(18):1995-2014. doi: 10.1002/cmdc.201600298. Epub 2016 Jul 29. ChemMedChem. 2016. PMID: 27471138
New classes of potent and bioavailable human renin inhibitors.
Remen L, Bezençon O, Richard-Bildstein S, Bur D, Prade L, Corminboeuf O, Boss C, Grisostomi C, Sifferlen T, Strickner P, Hess P, Delahaye S, Treiber A, Weller T, Binkert C, Steiner B, Fischli W. Remen L, et al. Among authors: fischli w. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6762-5. doi: 10.1016/j.bmcl.2009.09.104. Epub 2009 Oct 1. Bioorg Med Chem Lett. 2009. PMID: 19853442
Piperidine-renin inhibitors compounds with improved physicochemical properties.
Güller R, Binggeli A, Breu V, Bur D, Fischli W, Hirth G, Jenny C, Kansy M, Montavon F, Müller M, Oefner C, Stadler H, Vieira E, Wilhelm M, Wostl W, Märki HP. Güller R, et al. Among authors: fischli w. Bioorg Med Chem Lett. 1999 May 17;9(10):1403-8. doi: 10.1016/s0960-894x(99)00196-1. Bioorg Med Chem Lett. 1999. PMID: 10360745
Design and preparation of potent, nonpeptidic, bioavailable renin inhibitors.
Bezençon O, Bur D, Weller T, Richard-Bildstein S, Remen L, Sifferlen T, Corminboeuf O, Grisostomi C, Boss C, Prade L, Delahaye S, Treiber A, Strickner P, Binkert C, Hess P, Steiner B, Fischli W. Bezençon O, et al. Among authors: fischli w. J Med Chem. 2009 Jun 25;52(12):3689-702. doi: 10.1021/jm900022f. J Med Chem. 2009. PMID: 19358611
The discovery of N-[5-(4-bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-N'-propylsulfamide (Macitentan), an orally active, potent dual endothelin receptor antagonist.
Bolli MH, Boss C, Binkert C, Buchmann S, Bur D, Hess P, Iglarz M, Meyer S, Rein J, Rey M, Treiber A, Clozel M, Fischli W, Weller T. Bolli MH, et al. Among authors: fischli w. J Med Chem. 2012 Sep 13;55(17):7849-61. doi: 10.1021/jm3009103. Epub 2012 Aug 16. J Med Chem. 2012. PMID: 22862294
Bis-sulfonamides as endothelin receptor antagonists.
Boss C, Bolli MH, Weller T, Fischli W, Clozel M. Boss C, et al. Among authors: fischli w. Bioorg Med Chem Lett. 2003 Mar 10;13(5):951-4. doi: 10.1016/s0960-894x(02)01083-1. Bioorg Med Chem Lett. 2003. PMID: 12617928
Novel benzo[1,4]diazepin-2-one derivatives as endothelin receptor antagonists.
Bolli MH, Marfurt J, Grisostomi C, Boss C, Binkert C, Hess P, Treiber A, Thorin E, Morrison K, Buchmann S, Bur D, Ramuz H, Clozel M, Fischli W, Weller T. Bolli MH, et al. Among authors: fischli w. J Med Chem. 2004 May 20;47(11):2776-95. doi: 10.1021/jm031115r. J Med Chem. 2004. PMID: 15139756
74 results