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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1949 1
1952 1
1953 1
1956 1
1958 1
1959 2
1960 2
1961 1
1964 1
1965 3
1978 1
1981 1
1986 1
2002 2
2003 1
2004 7
2006 6
2007 3
2008 1
2010 3
2011 6
2012 5
2013 7
2014 2
2015 4
2016 8
2017 7
2018 10
2019 4
2020 5
2021 12
2022 14
2023 10
2024 3

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129 results

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Page 1
Automated Design of Efficient and Functionally Diverse Enzyme Repertoires.
Khersonsky O, Lipsh R, Avizemer Z, Ashani Y, Goldsmith M, Leader H, Dym O, Rogotner S, Trudeau DL, Prilusky J, Amengual-Rigo P, Guallar V, Tawfik DS, Fleishman SJ. Khersonsky O, et al. Among authors: fleishman sj. Mol Cell. 2018 Oct 4;72(1):178-186.e5. doi: 10.1016/j.molcel.2018.08.033. Epub 2018 Sep 27. Mol Cell. 2018. PMID: 30270109 Free PMC article.
Editorial overview: Engineering and design.
Fleishman SJ, Mariuzza RA. Fleishman SJ, et al. Curr Opin Struct Biol. 2022 Aug;75:102437. doi: 10.1016/ Epub 2022 Jul 21. Curr Opin Struct Biol. 2022. PMID: 35872560 Free PMC article. No abstract available.
Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability.
Goldenzweig A, Goldsmith M, Hill SE, Gertman O, Laurino P, Ashani Y, Dym O, Unger T, Albeck S, Prilusky J, Lieberman RL, Aharoni A, Silman I, Sussman JL, Tawfik DS, Fleishman SJ. Goldenzweig A, et al. Among authors: fleishman sj. Mol Cell. 2016 Jul 21;63(2):337-346. doi: 10.1016/j.molcel.2016.06.012. Epub 2016 Jul 14. Mol Cell. 2016. PMID: 27425410 Free PMC article.
Computational optimization of antibody humanness and stability by systematic energy-based ranking.
Tennenhouse A, Khmelnitsky L, Khalaila R, Yeshaya N, Noronha A, Lindzen M, Makowski EK, Zaretsky I, Sirkis YF, Galon-Wolfenson Y, Tessier PM, Abramson J, Yarden Y, Fass D, Fleishman SJ. Tennenhouse A, et al. Among authors: fleishman sj. Nat Biomed Eng. 2024 Jan;8(1):30-44. doi: 10.1038/s41551-023-01079-1. Epub 2023 Aug 7. Nat Biomed Eng. 2024. PMID: 37550425
Computationally designed hyperactive Cas9 enzymes.
Vos PD, Rossetti G, Mantegna JL, Siira SJ, Gandadireja AP, Bruce M, Raven SA, Khersonsky O, Fleishman SJ, Filipovska A, Rackham O. Vos PD, et al. Among authors: fleishman sj. Nat Commun. 2022 May 31;13(1):3023. doi: 10.1038/s41467-022-30598-9. Nat Commun. 2022. PMID: 35641498 Free PMC article.
Direct-MS analysis of antibody-antigen complexes.
Vimer S, Ben-Nissan G, Marty M, Fleishman SJ, Sharon M. Vimer S, et al. Among authors: fleishman sj. Proteomics. 2021 Nov;21(21-22):e2000300. doi: 10.1002/pmic.202000300. Epub 2021 Aug 9. Proteomics. 2021. PMID: 34310051 Free PMC article.
Computational design of protein-protein interactions.
Schreiber G, Fleishman SJ. Schreiber G, et al. Among authors: fleishman sj. Curr Opin Struct Biol. 2013 Dec;23(6):903-10. doi: 10.1016/ Epub 2013 Aug 29. Curr Opin Struct Biol. 2013. PMID: 23993666 Review.
Combinatorial assembly and design of enzymes.
Lipsh-Sokolik R, Khersonsky O, Schröder SP, de Boer C, Hoch SY, Davies GJ, Overkleeft HS, Fleishman SJ. Lipsh-Sokolik R, et al. Among authors: fleishman sj. Science. 2023 Jan 13;379(6628):195-201. doi: 10.1126/science.ade9434. Epub 2023 Jan 12. Science. 2023. PMID: 36634164
What Have We Learned from Design of Function in Large Proteins?
Khersonsky O, Fleishman SJ. Khersonsky O, et al. Among authors: fleishman sj. Biodes Res. 2022 Mar 8;2022:9787581. doi: 10.34133/2022/9787581. eCollection 2022. Biodes Res. 2022. PMID: 37850148 Free PMC article. Review.
129 results