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Non-canonical Hedgehog signaling mediates profibrotic hematopoiesis-stroma crosstalk in myeloproliferative neoplasms.
Pritchard JE, Pearce JE, Snoeren IAM, Fuchs SNR, Götz K, Peisker F, Wagner S, Benabid A, Lutterbach N, Klöker V, Nagai JS, Hannani MT, Galyga AK, Sistemich E, Banjanin B, Flosdorf N, Bindels E, Olschok K, Biaesch K, Chatain N, Bhagwat N, Dunbar A, Sarkis R, Naveiras O, Berres ML, Koschmieder S, Levine RL, Costa IG, Gleitz HFE, Kramann R, Schneider RK. Pritchard JE, et al. Among authors: flosdorf n. Cell Rep. 2024 Jan 23;43(1):113608. doi: 10.1016/j.celrep.2023.113608. Epub 2023 Dec 20. Cell Rep. 2024. PMID: 38117649 Free PMC article.
Proinflammatory phenotype of iPS cell-derived JAK2 V617F megakaryocytes induces fibrosis in 3D in vitro bone marrow niche.
Flosdorf N, Böhnke J, de Toledo MAS, Lutterbach N, Lerma VG, Graßhoff M, Olschok K, Gupta S, Tharmapalan V, Schmitz S, Götz K, Schüler HM, Maurer A, Sontag S, Küstermann C, Seré K, Wagner W, Costa IG, Brümmendorf TH, Koschmieder S, Chatain N, Castilho M, Schneider RK, Zenke M. Flosdorf N, et al. Stem Cell Reports. 2024 Feb 13;19(2):224-238. doi: 10.1016/j.stemcr.2023.12.011. Epub 2024 Jan 25. Stem Cell Reports. 2024. PMID: 38278152 Free PMC article.
Cellular aging is accelerated in the malignant clone of myeloproliferative neoplasms.
Vieri M, Tharmapalan V, Kalmer M, Baumeister J, Nikolić M, Schnitker M, Kirschner M, Flosdorf N, de Toledo MAS, Zenke M, Koschmieder S, Brümmendorf TH, Beier F, Wagner W. Vieri M, et al. Among authors: flosdorf n. Blood Cancer J. 2023 Nov 6;13(1):164. doi: 10.1038/s41408-023-00936-1. Blood Cancer J. 2023. PMID: 37926720 Free PMC article. No abstract available.
Human DC3 Antigen Presenting Dendritic Cells From Induced Pluripotent Stem Cells.
Satoh T, Toledo MAS, Boehnke J, Olschok K, Flosdorf N, Götz K, Küstermann C, Sontag S, Seré K, Koschmieder S, Brümmendorf TH, Chatain N, Tagawa YI, Zenke M. Satoh T, et al. Among authors: flosdorf n. Front Cell Dev Biol. 2021 Jul 22;9:667304. doi: 10.3389/fcell.2021.667304. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34368123 Free PMC article.