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Page 1
Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry.
Zhang F, Wei K, Slowikowski K, Fonseka CY, Rao DA, Kelly S, Goodman SM, Tabechian D, Hughes LB, Salomon-Escoto K, Watts GFM, Jonsson AH, Rangel-Moreno J, Meednu N, Rozo C, Apruzzese W, Eisenhaure TM, Lieb DJ, Boyle DL, Mandelin AM 2nd; Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Consortium; Boyce BF, DiCarlo E, Gravallese EM, Gregersen PK, Moreland L, Firestein GS, Hacohen N, Nusbaum C, Lederer JA, Perlman H, Pitzalis C, Filer A, Holers VM, Bykerk VP, Donlin LT, Anolik JH, Brenner MB, Raychaudhuri S. Zhang F, et al. Among authors: fonseka cy. Nat Immunol. 2019 Jul;20(7):928-942. doi: 10.1038/s41590-019-0378-1. Epub 2019 May 6. Nat Immunol. 2019. PMID: 31061532 Free PMC article.
Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis.
Rao DA, Gurish MF, Marshall JL, Slowikowski K, Fonseka CY, Liu Y, Donlin LT, Henderson LA, Wei K, Mizoguchi F, Teslovich NC, Weinblatt ME, Massarotti EM, Coblyn JS, Helfgott SM, Lee YC, Todd DJ, Bykerk VP, Goodman SM, Pernis AB, Ivashkiv LB, Karlson EW, Nigrovic PA, Filer A, Buckley CD, Lederer JA, Raychaudhuri S, Brenner MB. Rao DA, et al. Among authors: fonseka cy. Nature. 2017 Feb 1;542(7639):110-114. doi: 10.1038/nature20810. Nature. 2017. PMID: 28150777 Free PMC article.
Multimodal single-cell approaches shed light on T cell heterogeneity.
Nathan A, Baglaenko Y, Fonseka CY, Beynor JI, Raychaudhuri S. Nathan A, et al. Among authors: fonseka cy. Curr Opin Immunol. 2019 Dec;61:17-25. doi: 10.1016/j.coi.2019.07.002. Epub 2019 Aug 17. Curr Opin Immunol. 2019. PMID: 31430664 Free PMC article. Review.
PD-1hiCXCR5- T peripheral helper cells promote B cell responses in lupus via MAF and IL-21.
Bocharnikov AV, Keegan J, Wacleche VS, Cao Y, Fonseka CY, Wang G, Muise ES, Zhang KX, Arazi A, Keras G, Li ZJ, Qu Y, Gurish MF, Petri M, Buyon JP, Putterman C, Wofsy D, James JA, Guthridge JM, Diamond B, Anolik JH, Mackey MF, Alves SE, Nigrovic PA, Costenbader KH, Brenner MB, Lederer JA, Rao DA; Accelerating Medicines Partnership (AMP) RA/SLE Network. Bocharnikov AV, et al. Among authors: fonseka cy. JCI Insight. 2019 Oct 17;4(20):e130062. doi: 10.1172/jci.insight.130062. JCI Insight. 2019. PMID: 31536480 Free PMC article.
Versatile design and synthesis platform for visualizing genomes with Oligopaint FISH probes.
Beliveau BJ, Joyce EF, Apostolopoulos N, Yilmaz F, Fonseka CY, McCole RB, Chang Y, Li JB, Senaratne TN, Williams BR, Rouillard JM, Wu CT. Beliveau BJ, et al. Among authors: fonseka cy. Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21301-6. doi: 10.1073/pnas.1213818110. Epub 2012 Dec 11. Proc Natl Acad Sci U S A. 2012. PMID: 23236188 Free PMC article.
Mixed-effects association of single cells identifies an expanded effector CD4+ T cell subset in rheumatoid arthritis.
Fonseka CY, Rao DA, Teslovich NC, Korsunsky I, Hannes SK, Slowikowski K, Gurish MF, Donlin LT, Lederer JA, Weinblatt ME, Massarotti EM, Coblyn JS, Helfgott SM, Todd DJ, Bykerk VP, Karlson EW, Ermann J, Lee YC, Brenner MB, Raychaudhuri S. Fonseka CY, et al. Sci Transl Med. 2018 Oct 17;10(463):eaaq0305. doi: 10.1126/scitranslmed.aaq0305. Sci Transl Med. 2018. PMID: 30333237 Free PMC article.
Single-molecule super-resolution imaging of chromosomes and in situ haplotype visualization using Oligopaint FISH probes.
Beliveau BJ, Boettiger AN, Avendaño MS, Jungmann R, McCole RB, Joyce EF, Kim-Kiselak C, Bantignies F, Fonseka CY, Erceg J, Hannan MA, Hoang HG, Colognori D, Lee JT, Shih WM, Yin P, Zhuang X, Wu CT. Beliveau BJ, et al. Among authors: fonseka cy. Nat Commun. 2015 May 12;6:7147. doi: 10.1038/ncomms8147. Nat Commun. 2015. PMID: 25962338 Free PMC article.