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Page 1
Discovery and Development of S6821 and S7958 as Potent TAS2R8 Antagonists.
Fotsing JR, Darmohusodo V, Patron AP, Ching BW, Brady T, Arellano M, Chen Q, Davis TJ, Liu H, Servant G, Zhang L, Williams M, Saganich M, Ditschun T, Tachdjian C, Karanewsky DS. Fotsing JR, et al. J Med Chem. 2020 May 14;63(9):4957-4977. doi: 10.1021/acs.jmedchem.0c00388. Epub 2020 Apr 24. J Med Chem. 2020. PMID: 32330040
Toxicological evaluation of the flavour ingredient N-(1-((4-amino-2,2-dioxido-1H-benzo[c][1,2,6]thiadiazin-5-yl)oxy)-2-methylpropan-2-yl)-2,6-dimethylisonicotinamide (S2218).
Karanewsky DS, Servant G, Liu H, Chi B, Ida L, Saganich M, Werner S, Fotsing JR, Patron A, Tachdjian C, Arthur A. Karanewsky DS, et al. Among authors: fotsing jr. Toxicol Rep. 2017 Sep 14;4:507-520. doi: 10.1016/j.toxrep.2017.09.004. eCollection 2017. Toxicol Rep. 2017. PMID: 28959681 Free PMC article.
Generation of candidate ligands for nicotinic acetylcholine receptors via in situ click chemistry with a soluble acetylcholine binding protein template.
Grimster NP, Stump B, Fotsing JR, Weide T, Talley TT, Yamauchi JG, Nemecz Á, Kim C, Ho KY, Sharpless KB, Taylor P, Fokin VV. Grimster NP, et al. Among authors: fotsing jr. J Am Chem Soc. 2012 Apr 18;134(15):6732-40. doi: 10.1021/ja3001858. Epub 2012 Apr 6. J Am Chem Soc. 2012. PMID: 22394239 Free PMC article.