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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 1
2015 2
2016 1
2017 1
2018 1
2019 1
2021 1
2022 0
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7 results
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Page 1
Discovery and Characterization of a Potent Interleukin-6 Binding Peptide with Neutralizing Activity In Vivo.
Ranganath S, Bhandari A, Avitahl-Curtis N, McMahon J, Wachtel D, Zhang J, Leitheiser C, Bernier SG, Liu G, Tran TT, Celino H, Tobin J, Jung J, Zhao H, Glen KE, Graul C, Griffin A, Schairer WC, Higgins C, Reza TL, Mowe E, Rivers S, Scott S, Monreal A, Shea C, Bourne G, Coons C, Smith A, Tang K, Mandyam RA, Masferrer J, Liu D, Patel DV, Fretzen A, Murphy CA, Milne GT, Smythe ML, Carlson KE. Ranganath S, et al. Among authors: fretzen a. PLoS One. 2015 Nov 10;10(11):e0141330. doi: 10.1371/journal.pone.0141330. eCollection 2015. PLoS One. 2015. PMID: 26555695 Free PMC article.
Discovery of IWP-051, a Novel Orally Bioavailable sGC Stimulator with Once-Daily Dosing Potential in Humans.
Nakai T, Perl NR, Barden TC, Carvalho A, Fretzen A, Germano P, Im GY, Jin H, Kim C, Lee TW, Long K, Moore J, Rohde JM, Sarno R, Segal C, Solberg EO, Tobin J, Zimmer DP, Currie MG. Nakai T, et al. Among authors: fretzen a. ACS Med Chem Lett. 2016 Feb 24;7(5):465-9. doi: 10.1021/acsmedchemlett.5b00479. eCollection 2016 May 12. ACS Med Chem Lett. 2016. PMID: 27190594 Free PMC article.
Disease-modifying effects of edasalonexent, an NF-κB inhibitor, in young boys with Duchenne muscular dystrophy: Results of the MoveDMD phase 2 and open label extension trial.
Finkel RS, Finanger E, Vandenborne K, Sweeney HL, Tennekoon G, Shieh PB, Willcocks R, Walter G, Rooney WD, Forbes SC, Triplett WT, Yum SW, Mancini M, MacDougall J, Fretzen A, Bista P, Nichols A, Donovan JM. Finkel RS, et al. Among authors: fretzen a. Neuromuscul Disord. 2021 May;31(5):385-396. doi: 10.1016/j.nmd.2021.02.001. Epub 2021 Feb 4. Neuromuscul Disord. 2021. PMID: 33678513 Free article. Clinical Trial.
MRP4 Modulation of the Guanylate Cyclase-C/cGMP Pathway: Effects on Linaclotide-Induced Electrolyte Secretion and cGMP Efflux.
Tchernychev B, Ge P, Kessler MM, Solinga RM, Wachtel D, Tobin JV, Thomas SR, Lunte CE, Fretzen A, Hannig G, Bryant AP, Kurtz CB, Currie MG, Silos-Santiago I. Tchernychev B, et al. Among authors: fretzen a. J Pharmacol Exp Ther. 2015 Oct;355(1):48-56. doi: 10.1124/jpet.115.224329. Epub 2015 Jul 27. J Pharmacol Exp Ther. 2015. PMID: 26216942
Inhibition of filamentation can be used to treat disseminated candidiasis.
Saville SP, Lazzell AL, Bryant AP, Fretzen A, Monreal A, Solberg EO, Monteagudo C, Lopez-Ribot JL, Milne GT. Saville SP, et al. Among authors: fretzen a. Antimicrob Agents Chemother. 2006 Oct;50(10):3312-6. doi: 10.1128/AAC.00628-06. Antimicrob Agents Chemother. 2006. PMID: 17005810 Free PMC article.