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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1913 1
1914 1
1932 1
1933 1
1935 1
1945 1
1946 7
1947 5
1948 1
1949 6
1950 4
1952 1
1953 8
1954 1
1955 4
1956 5
1957 3
1958 4
1959 3
1960 5
1961 3
1962 7
1963 4
1964 12
1965 6
1966 9
1967 9
1968 9
1969 11
1970 6
1971 10
1972 16
1973 7
1974 12
1975 10
1976 5
1977 14
1978 18
1979 19
1980 19
1981 11
1982 11
1983 15
1984 19
1985 17
1986 22
1987 25
1988 28
1989 22
1990 24
1991 36
1992 41
1993 38
1994 39
1995 37
1996 36
1997 32
1998 30
1999 32
2000 22
2001 32
2002 23
2003 35
2004 26
2005 33
2006 52
2007 44
2008 26
2009 43
2010 37
2011 35
2012 46
2013 48
2014 43
2015 44
2016 43
2017 39
2018 51
2019 49
2020 54
2021 49
2022 31
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Article type
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Search Results

1,600 results
Results by year
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Page 1
Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors.
Vasan N, Razavi P, Johnson JL, Shao H, Shah H, Antoine A, Ladewig E, Gorelick A, Lin TY, Toska E, Xu G, Kazmi A, Chang MT, Taylor BS, Dickler MN, Jhaveri K, Chandarlapaty S, Rabadan R, Reznik E, Smith ML, Sebra R, Schimmoller F, Wilson TR, Friedman LS, Cantley LC, Scaltriti M, Baselga J. Vasan N, et al. Among authors: friedman ls. Science. 2019 Nov 8;366(6466):714-723. doi: 10.1126/science.aaw9032. Science. 2019. PMID: 31699932 Free PMC article.
GDC-9545 (Giredestrant): A Potent and Orally Bioavailable Selective Estrogen Receptor Antagonist and Degrader with an Exceptional Preclinical Profile for ER+ Breast Cancer.
Liang J, Zbieg JR, Blake RA, Chang JH, Daly S, DiPasquale AG, Friedman LS, Gelzleichter T, Gill M, Giltnane JM, Goodacre S, Guan J, Hartman SJ, Ingalla ER, Kategaya L, Kiefer JR, Kleinheinz T, Labadie SS, Lai T, Li J, Liao J, Liu Z, Mody V, McLean N, Metcalfe C, Nannini MA, Oeh J, O'Rourke MG, Ortwine DF, Ran Y, Ray NC, Roussel F, Sambrone A, Sampath D, Schutt LK, Vinogradova M, Wai J, Wang T, Wertz IE, White JR, Yeap SK, Young A, Zhang B, Zheng X, Zhou W, Zhong Y, Wang X. Liang J, et al. Among authors: friedman ls. J Med Chem. 2021 Aug 26;64(16):11841-11856. doi: 10.1021/acs.jmedchem.1c00847. Epub 2021 Jul 12. J Med Chem. 2021. PMID: 34251202
Therapeutic Ligands Antagonize Estrogen Receptor Function by Impairing Its Mobility.
Guan J, Zhou W, Hafner M, Blake RA, Chalouni C, Chen IP, De Bruyn T, Giltnane JM, Hartman SJ, Heidersbach A, Houtman R, Ingalla E, Kategaya L, Kleinheinz T, Li J, Martin SE, Modrusan Z, Nannini M, Oeh J, Ubhayakar S, Wang X, Wertz IE, Young A, Yu M, Sampath D, Hager JH, Friedman LS, Daemen A, Metcalfe C. Guan J, et al. Among authors: friedman ls. Cell. 2019 Aug 8;178(4):949-963.e18. doi: 10.1016/j.cell.2019.06.026. Epub 2019 Jul 25. Cell. 2019. PMID: 31353221 Free article.
Approaches to data analyses of clinical trials.
Furberg CD, Friedman LM. Furberg CD, et al. Among authors: friedman lm. Prog Cardiovasc Dis. 2012 Jan-Feb;54(4):330-4. doi: 10.1016/j.pcad.2011.07.002. Prog Cardiovasc Dis. 2012. PMID: 22225999
RTK-Dependent Inducible Degradation of Mutant PI3Kα Drives GDC-0077 (Inavolisib) Efficacy.
Song KW, Edgar KA, Hanan EJ, Hafner M, Oeh J, Merchant M, Sampath D, Nannini MA, Hong R, Phu L, Forrest WF, Stawiski E, Schmidt S, Endres N, Guan J, Wallin JJ, Cheong J, Plise EG, Lewis Phillips GD, Salphati L, Heffron TP, Olivero AG, Malek S, Staben ST, Kirkpatrick DS, Dey A, Friedman LS. Song KW, et al. Among authors: friedman ls. Cancer Discov. 2022 Jan;12(1):204-219. doi: 10.1158/2159-8290.CD-21-0072. Epub 2021 Sep 20. Cancer Discov. 2022. PMID: 34544753
Brain development in ADHD.
Friedman LA, Rapoport JL. Friedman LA, et al. Curr Opin Neurobiol. 2015 Feb;30:106-11. doi: 10.1016/j.conb.2014.11.007. Epub 2014 Dec 9. Curr Opin Neurobiol. 2015. PMID: 25500059 Review.
1,600 results