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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 1
1979 1
1980 3
1981 1
1983 1
1984 3
1985 4
1986 2
1987 5
1988 3
1989 3
1990 4
1991 11
1992 12
1993 12
1994 13
1995 11
1996 6
1997 7
1998 4
1999 6
2000 2
2001 1
2002 1
2003 6
2004 6
2005 6
2006 5
2007 9
2008 5
2009 17
2010 16
2011 9
2012 20
2013 15
2014 14
2015 8
2016 11
2017 10
2018 5
2019 8
2020 14
2021 12
2022 9
2023 6

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309 results

Results by year

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Page 1
RTK-Dependent Inducible Degradation of Mutant PI3Kα Drives GDC-0077 (Inavolisib) Efficacy.
Song KW, Edgar KA, Hanan EJ, Hafner M, Oeh J, Merchant M, Sampath D, Nannini MA, Hong R, Phu L, Forrest WF, Stawiski E, Schmidt S, Endres N, Guan J, Wallin JJ, Cheong J, Plise EG, Lewis Phillips GD, Salphati L, Heffron TP, Olivero AG, Malek S, Staben ST, Kirkpatrick DS, Dey A, Friedman LS. Song KW, et al. Among authors: friedman ls. Cancer Discov. 2022 Jan;12(1):204-219. doi: 10.1158/2159-8290.CD-21-0072. Epub 2021 Sep 20. Cancer Discov. 2022. PMID: 34544753 Free PMC article.
Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors.
Vasan N, Razavi P, Johnson JL, Shao H, Shah H, Antoine A, Ladewig E, Gorelick A, Lin TY, Toska E, Xu G, Kazmi A, Chang MT, Taylor BS, Dickler MN, Jhaveri K, Chandarlapaty S, Rabadan R, Reznik E, Smith ML, Sebra R, Schimmoller F, Wilson TR, Friedman LS, Cantley LC, Scaltriti M, Baselga J. Vasan N, et al. Among authors: friedman ls. Science. 2019 Nov 8;366(6466):714-723. doi: 10.1126/science.aaw9032. Science. 2019. PMID: 31699932 Free PMC article.
GDC-9545 (Giredestrant): A Potent and Orally Bioavailable Selective Estrogen Receptor Antagonist and Degrader with an Exceptional Preclinical Profile for ER+ Breast Cancer.
Liang J, Zbieg JR, Blake RA, Chang JH, Daly S, DiPasquale AG, Friedman LS, Gelzleichter T, Gill M, Giltnane JM, Goodacre S, Guan J, Hartman SJ, Ingalla ER, Kategaya L, Kiefer JR, Kleinheinz T, Labadie SS, Lai T, Li J, Liao J, Liu Z, Mody V, McLean N, Metcalfe C, Nannini MA, Oeh J, O'Rourke MG, Ortwine DF, Ran Y, Ray NC, Roussel F, Sambrone A, Sampath D, Schutt LK, Vinogradova M, Wai J, Wang T, Wertz IE, White JR, Yeap SK, Young A, Zhang B, Zheng X, Zhou W, Zhong Y, Wang X. Liang J, et al. Among authors: friedman ls. J Med Chem. 2021 Aug 26;64(16):11841-11856. doi: 10.1021/acs.jmedchem.1c00847. Epub 2021 Jul 12. J Med Chem. 2021. PMID: 34251202
Discovery of GDC-0077 (Inavolisib), a Highly Selective Inhibitor and Degrader of Mutant PI3Kα.
Hanan EJ, Braun MG, Heald RA, MacLeod C, Chan C, Clausen S, Edgar KA, Eigenbrot C, Elliott R, Endres N, Friedman LS, Gogol E, Gu XH, Thibodeau RH, Jackson PS, Kiefer JR, Knight JD, Nannini M, Narukulla R, Pace A, Pang J, Purkey HE, Salphati L, Sampath D, Schmidt S, Sideris S, Song K, Sujatha-Bhaskar S, Ultsch M, Wallweber H, Xin J, Yeap S, Young A, Zhong Y, Staben ST. Hanan EJ, et al. Among authors: friedman ls. J Med Chem. 2022 Dec 22;65(24):16589-16621. doi: 10.1021/acs.jmedchem.2c01422. Epub 2022 Dec 1. J Med Chem. 2022. PMID: 36455032
Liver transplantation.
Muñoz SJ, Friedman LS. Muñoz SJ, et al. Among authors: friedman ls. Med Clin North Am. 1989 Jul;73(4):1011-39. doi: 10.1016/s0025-7125(16)30651-4. Med Clin North Am. 1989. PMID: 2657259 Free article. Review.
Therapeutic Ligands Antagonize Estrogen Receptor Function by Impairing Its Mobility.
Guan J, Zhou W, Hafner M, Blake RA, Chalouni C, Chen IP, De Bruyn T, Giltnane JM, Hartman SJ, Heidersbach A, Houtman R, Ingalla E, Kategaya L, Kleinheinz T, Li J, Martin SE, Modrusan Z, Nannini M, Oeh J, Ubhayakar S, Wang X, Wertz IE, Young A, Yu M, Sampath D, Hager JH, Friedman LS, Daemen A, Metcalfe C. Guan J, et al. Among authors: friedman ls. Cell. 2019 Aug 8;178(4):949-963.e18. doi: 10.1016/j.cell.2019.06.026. Epub 2019 Jul 25. Cell. 2019. PMID: 31353221 Free article.
Irritable bowel syndrome.
Lynn RB, Friedman LS. Lynn RB, et al. Among authors: friedman ls. N Engl J Med. 1993 Dec 23;329(26):1940-5. doi: 10.1056/NEJM199312233292608. N Engl J Med. 1993. PMID: 8305064 Review. No abstract available.
Lower gastrointestinal bleeding.
Bounds BC, Friedman LS. Bounds BC, et al. Among authors: friedman ls. Gastroenterol Clin North Am. 2003 Dec;32(4):1107-25. doi: 10.1016/s0889-8553(03)00086-4. Gastroenterol Clin North Am. 2003. PMID: 14696299 Review.
Delta agent hepatitis.
Chatzinoff M, Friedman LS. Chatzinoff M, et al. Among authors: friedman ls. Infect Dis Clin North Am. 1987 Sep;1(3):529-45. Infect Dis Clin North Am. 1987. PMID: 3332883 Review.
Introduction of Clinical Practice Update Committee Articles.
Friedman LS, Inadomi JM, Kalloo AM, Katzka DA, Kim LS, Koch J, Lieberman D, Lichtenstein GR, Lim JK, Pandolfino JE, Shin AS, Siedler MR. Friedman LS, et al. Clin Gastroenterol Hepatol. 2017 Jan;15(1):4. doi: 10.1016/j.cgh.2016.11.011. Clin Gastroenterol Hepatol. 2017. PMID: 27979048 No abstract available.
309 results