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1993 1
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Page 1
Bicyclo((aryl)methyl)benzamides as inhibitors of GlyT1.
Varnes JG, Xiong H, Forst JM, Holmquist CR, Ernst GE, Frietze W, Dembofsky B, Andisik DW, Palmer WE, Hinkley L, Steelman GB, Wilkins DE, Tian G, Jonak G, Potts WM, Wang X, Brugel TA, Alhambra C, Wood MW, Veale CA, Albert JS. Varnes JG, et al. Among authors: frietze w. Bioorg Med Chem Lett. 2018 Apr 1;28(6):1043-1049. doi: 10.1016/j.bmcl.2018.02.029. Epub 2018 Feb 14. Bioorg Med Chem Lett. 2018. PMID: 29486970
Roles of UGT, P450, and Gut Microbiota in the Metabolism of Epacadostat in Humans.
Boer J, Young-Sciame R, Lee F, Bowman KJ, Yang X, Shi JG, Nedza FM, Frietze W, Galya L, Combs AP, Yeleswaram S, Diamond S. Boer J, et al. Among authors: frietze w. Drug Metab Dispos. 2016 Oct;44(10):1668-74. doi: 10.1124/dmd.116.070680. Epub 2016 Jul 25. Drug Metab Dispos. 2016. PMID: 27457784
Multiparameter exploration of piperazine derivatives as δ-opioid receptor agonists for CNS indications.
McCauley JP Jr, Dantzman CL, King MM, Ernst GE, Wang X, Brush K, Palmer WE, Frietze W, Andisik DW, Hoesch V, Doring K, Hulsizer J, Bui KH, Liu J, Hudzik TJ, Wesolowski SS. McCauley JP Jr, et al. Among authors: frietze w. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1169-73. doi: 10.1016/j.bmcl.2011.11.088. Epub 2011 Dec 7. Bioorg Med Chem Lett. 2012. PMID: 22197139
Discovery of an orally active series of isoxazoline glycoprotein IIb/IIIa antagonists.
Xue CB, Wityak J, Sielecki TM, Pinto DJ, Batt DG, Cain GA, Sworin M, Rockwell AL, Roderick JJ, Wang S, Orwat MJ, Frietze WE, Bostrom LL, Liu J, Higley CA, Rankin FW, Tobin AE, Emmett G, Lalka GK, Sze JY, Di Meo SV, Mousa SA, Thoolen MJ, Racanelli AL, Olson RE, et al. Xue CB, et al. Among authors: frietze we. J Med Chem. 1997 Jun 20;40(13):2064-84. doi: 10.1021/jm960799i. J Med Chem. 1997. PMID: 9207948
MEK inhibitors: the chemistry and biological activity of U0126, its analogs, and cyclization products.
Duncia JV, Santella JB 3rd, Higley CA, Pitts WJ, Wityak J, Frietze WE, Rankin FW, Sun JH, Earl RA, Tabaka AC, Teleha CA, Blom KF, Favata MF, Manos EJ, Daulerio AJ, Stradley DA, Horiuchi K, Copeland RA, Scherle PA, Trzaskos JM, Magolda RL, Trainor GL, Wexler RR, Hobbs FW, Olson RE. Duncia JV, et al. Among authors: frietze we. Bioorg Med Chem Lett. 1998 Oct 20;8(20):2839-44. doi: 10.1016/s0960-894x(98)00522-8. Bioorg Med Chem Lett. 1998. PMID: 9873633
4-Piperidin-4-ylidenemethyl-benzamides as δ-opioid receptor agonists for CNS indications: identifying clinical candidates.
Dantzman CL, King MM, Ernst GE, Wang X, McCauley JP Jr, Andisik DW, Brush K, Bui KH, Frietze W, Hoesch V, Liu J, Palmer WE, Spear N, Hudzik TJ, Wesolowski SS. Dantzman CL, et al. Among authors: frietze w. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1174-8. doi: 10.1016/j.bmcl.2011.11.089. Epub 2011 Nov 30. Bioorg Med Chem Lett. 2012. PMID: 22197137
Orally active isoxazoline glycoprotein IIb/IIIa antagonists with extended duration of action.
Olson RE, Sielecki TM, Wityak J, Pinto DJ, Batt DG, Frietze WE, Liu J, Tobin AE, Orwat MJ, Di Meo SV, Houghton GC, Lalka GK, Mousa SA, Racanelli AL, Hausner EA, Kapil RP, Rabel SR, Thoolen MJ, Reilly TM, Anderson PS, Wexler RR. Olson RE, et al. Among authors: frietze we. J Med Chem. 1999 Apr 8;42(7):1178-92. doi: 10.1021/jm980348t. J Med Chem. 1999. PMID: 10197962