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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1986 1
1988 1
1991 1
1994 1
1995 3
1997 1
1998 2
1999 1
2001 4
2002 4
2003 3
2004 2
2005 5
2006 5
2007 4
2008 7
2009 15
2010 15
2011 17
2012 11
2013 15
2014 11
2015 12
2016 13
2017 13
2018 19
2019 18
2020 19
2021 7
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206 results
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Page 1
PROTAC-mediated crosstalk between E3 ligases.
Steinebach C , Kehm H , Lindner S , Vu LP , Köpff S , López Mármol Á , Weiler C , Wagner KG , Reichenzeller M , Krönke J , Gütschow M . Steinebach C , et al. Among authors: gutschow m. Chem Commun (Camb). 2019 Feb 5;55(12):1821-1824. doi: 10.1039/c8cc09541h. Chem Commun (Camb). 2019. PMID: 30672516
Homo-PROTACs for the Chemical Knockdown of Cereblon.
Steinebach C, Lindner S, Udeshi ND, Mani DC, Kehm H, Köpff S, Carr SA, Gütschow M, Krönke J. Steinebach C, et al. Among authors: gutschow m. ACS Chem Biol. 2018 Sep 21;13(9):2771-2782. doi: 10.1021/acschembio.8b00693. Epub 2018 Sep 5. ACS Chem Biol. 2018. PMID: 30118587
A whole-cell computational model predicts phenotype from genotype.
Karr JR, Sanghvi JC, Macklin DN, Gutschow MV, Jacobs JM, Bolival B Jr, Assad-Garcia N, Glass JI, Covert MW. Karr JR, et al. Among authors: gutschow mv. Cell. 2012 Jul 20;150(2):389-401. doi: 10.1016/j.cell.2012.05.044. Cell. 2012. PMID: 22817898 Free PMC article.
Lenalidomide and pomalidomide potently interfere with induction of myeloid-derived suppressor cells in multiple myeloma.
Kuwahara-Ota S, Shimura Y, Steinebach C, Isa R, Yamaguchi J, Nishiyama D, Fujibayashi Y, Takimoto-Shimomura T, Mizuno Y, Matsumura-Kimoto Y, Tsukamoto T, Chinen Y, Kobayashi T, Horiike S, Taniwaki M, Gütschow M, Kuroda J. Kuwahara-Ota S, et al. Among authors: gutschow m. Br J Haematol. 2020 Dec;191(5):784-795. doi: 10.1111/bjh.16881. Epub 2020 Jun 19. Br J Haematol. 2020. PMID: 32558939
Systematic exploration of different E3 ubiquitin ligases: an approach towards potent and selective CDK6 degraders.
Steinebach C, Ng YLD, Sosič I, Lee CS, Chen S, Lindner S, Vu LP, Bricelj A, Haschemi R, Monschke M, Steinwarz E, Wagner KG, Bendas G, Luo J, Gütschow M, Krönke J. Steinebach C, et al. Among authors: gutschow m. Chem Sci. 2020 Mar 4;11(13):3474-3486. doi: 10.1039/d0sc00167h. eCollection 2020 Apr 7. Chem Sci. 2020. PMID: 33133483 Free PMC article.
Can Cysteine Protease Cross-Class Inhibitors Achieve Selectivity?
Cianni L, Feldmann CW, Gilberg E, Gütschow M, Juliano L, Leitão A, Bajorath J, Montanari CA. Cianni L, et al. Among authors: gutschow m. J Med Chem. 2019 Dec 12;62(23):10497-10525. doi: 10.1021/acs.jmedchem.9b00683. Epub 2019 Aug 15. J Med Chem. 2019. PMID: 31361135 Review.
A MedChem toolbox for cereblon-directed PROTACs.
Steinebach C, Sosič I, Lindner S, Bricelj A, Kohl F, Ng YLD, Monschke M, Wagner KG, Krönke J, Gütschow M. Steinebach C, et al. Among authors: gutschow m. Medchemcomm. 2019 May 28;10(6):1037-1041. doi: 10.1039/c9md00185a. eCollection 2019 Jun 1. Medchemcomm. 2019. PMID: 31304001 Free PMC article.
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-6.
Vanden Eynde JJ, Mangoni AA, Rautio J, Leprince J, Azuma YT, García-Sosa AT, Hulme C, Jampilek J, Karaman R, Li W, Gomes PAC, Hadjipavlou-Litina D, Capasso R, Geronikaki A, Cerchia L, Sabatier JM, Ragno R, Tuccinardi T, Trabocchi A, Winum JY, Luque FJ, Prokai-Tatrai K, Spetea M, Gütschow M, Kosalec I, Guillou C, Vasconcelos MH, Kokotos G, Rastelli G, de Sousa ME, Manera C, Gemma S, Mangani S, Siciliano C, Galdiero S, Liu H, Scott PJH, de Los Ríos C, Agrofoglio LA, Collina S, Guedes RC, Muñoz-Torrero D. Vanden Eynde JJ, et al. Among authors: gutschow m. Molecules. 2019 Dec 28;25(1):119. doi: 10.3390/molecules25010119. Molecules. 2019. PMID: 31905602 Free PMC article.
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-5.
Mangoni AA, Eynde JJV, Jampilek J, Hadjipavlou-Litina D, Liu H, Reynisson J, Sousa ME, Gomes PAC, Prokai-Tatrai K, Tuccinardi T, Sabatier JM, Luque FJ, Rautio J, Karaman R, Vasconcelos MH, Gemma S, Galdiero S, Hulme C, Collina S, Gütschow M, Kokotos G, Siciliano C, Capasso R, Agrofoglio LA, Ragno R, Muñoz-Torrero D. Mangoni AA, et al. Among authors: gutschow m. Molecules. 2019 Jun 30;24(13):2415. doi: 10.3390/molecules24132415. Molecules. 2019. PMID: 31262039 Free PMC article.
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-7.
Gütschow M, Eynde JJV, Jampilek J, Kang C, Mangoni AA, Fossa P, Karaman R, Trabocchi A, Scott PJH, Reynisson J, Rapposelli S, Galdiero S, Winum JY, Brullo C, Prokai-Tatrai K, Sharma AK, Schapira M, Azuma YT, Cerchia L, Spetea M, Torri G, Collina S, Geronikaki A, García-Sosa AT, Vasconcelos MH, Sousa ME, Kosalec I, Tuccinardi T, Duarte IF, Salvador JAR, Bertinaria M, Pellecchia M, Amato J, Rastelli G, Gomes PAC, Guedes RC, Sabatier JM, Estévez-Braun A, Pagano B, Mangani S, Ragno R, Kokotos G, Brindisi M, González FV, Borges F, Miloso M, Rautio J, Muñoz-Torrero D. Gütschow M, et al. Molecules. 2020 Jun 28;25(13):2968. doi: 10.3390/molecules25132968. Molecules. 2020. PMID: 32605268 Free PMC article.
206 results
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