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Functional decomposition of metabolism allows a system-level quantification of fluxes and protein allocation towards specific metabolic functions.
Mori M, Cheng C, Taylor BR, Okano H, Hwa T. Mori M, et al. Nat Commun. 2023 Jul 13;14(1):4161. doi: 10.1038/s41467-023-39724-7. Nat Commun. 2023. PMID: 37443156 Free PMC article.
Here we establish a general theoretical framework (Functional Decomposition of Metabolism, FDM) to quantify the contribution of every metabolic reaction to metabolic functions, e.g. the synthesis of biomass building blocks. FDM allowed for a detailed quantification of the …
Here we establish a general theoretical framework (Functional Decomposition of Metabolism, FDM) to quantify the contribution of every metabo …
Weight loss-associated changes in acute effects of nateglinide on insulin secretion after glucose loading: results of glucose loading on 2 consecutive days.
Mori Y, Mamori S, Tajima N. Mori Y, et al. Diabetes Obes Metab. 2005 Mar;7(2):182-8. doi: 10.1111/j.1463-1326.2004.00384.x. Diabetes Obes Metab. 2005. PMID: 15715891
METHODS: Oral glucose tolerance testing (OGTT, 75 g) was performed in obese patients before and after weight loss on 2 consecutive days (first day OGTT without nateglinide, second day OGTT with nateglinide), to compare any weight loss associated changes in the nateglinide- …
METHODS: Oral glucose tolerance testing (OGTT, 75 g) was performed in obese patients before and after weight loss on 2 consecutive da …