Complete Genomic Landscape Reveals Hidden Evolutionary History and Selection Signature in Asian Water Buffaloes (Bubalus bubalis).
Si J, Dai D, Gorkhali NA, Wang M, Wang S, Sapkota S, Kadel RC, Sadaula A, Dhakal A, Faruque MO, Omar AI, Sari EM, Ashari H, Dagong MIA, Yindee M, Rushdi HE, Elregalaty H, Amin A, Radwan MA, Pham LD, Hulugalla WMMP, Silva GLLP, Zheng W, Mansoor S, Ali MB, Vahidi F, Al-Bayatti SA, Pauciullo A, Lenstra JA, Barker JSF, Fang L, Wu DD, Han J, Zhang Y.
Si J, et al.
Adv Sci (Weinh). 2024 Dec 4:e2407615. doi: 10.1002/advs.202407615. Online ahead of print.
Adv Sci (Weinh). 2024.
PMID: 39630943
Purifying selection prevented the accumulation of harmful loss-of-function variants in the Indonesian buffaloes. Genes that evolved rapidly (e.g., GKAP1) following differential selections in the river and swamp buffaloes are involved in their reproduction. Genes related to …
Purifying selection prevented the accumulation of harmful loss-of-function variants in the Indonesian buffaloes. Genes that evolved rapidly …