Development of a Recombinant Omicron BA.1 Subunit Vaccine Candidate in Pichia pastoris.
Kalyoncu S, Sayili D, Kuyucu AZ, Soyturk H, Gullu S, Ersayan B, Tarman IO, Avci ME, Mert O, Haskok U, Tekin E, Akinturk H, Orkut R, Demirtas A, Tilmensagir I, Ulker C, Gungor B, Inan M.
Kalyoncu S, et al.
Microb Biotechnol. 2025 Jan;18(1):e70077. doi: 10.1111/1751-7915.70077.
Microb Biotechnol. 2025.
PMID: 39815667
Free PMC article.
The receptor binding domain of Omicron BA.1 spike protein (RBD-Omicron) was produced at 0.35 g/L in supernatant. With a 60% recovery after two-step purification, RBD-Omicron showed 99% purity. ...
The receptor binding domain of Omicron BA.1 spike protein (RBD-Omicron) was produced at 0.35 g/L in supernatant. With a 60% recovery …