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Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease.
Salloway S, Sperling R, Fox NC, Blennow K, Klunk W, Raskind M, Sabbagh M, Honig LS, Porsteinsson AP, Ferris S, Reichert M, Ketter N, Nejadnik B, Guenzler V, Miloslavsky M, Wang D, Lu Y, Lull J, Tudor IC, Liu E, Grundman M, Yuen E, Black R, Brashear HR; Bapineuzumab 301 and 302 Clinical Trial Investigators. Salloway S, et al. N Engl J Med. 2014 Jan 23;370(4):322-33. doi: 10.1056/NEJMoa1304839. N Engl J Med. 2014. PMID: 24450891 Free PMC article. Clinical Trial.
Secondary outcome measures included findings on positron-emission tomographic amyloid imaging with the use of Pittsburgh compound B (PIB-PET) and cerebrospinal fluid phosphorylated tau (phospho-tau) concentrations. ...
Secondary outcome measures included findings on positron-emission tomographic amyloid imaging with the use of Pittsburgh compound B ( …
Bacteriological profile of raw, frozen chicken nuggets.
Eglezos S, Dykes GA, Huang B, Fegan N, Stuttard E. Eglezos S, et al. J Food Prot. 2008 Mar;71(3):613-5. doi: 10.4315/0362-028x-71.3.613. J Food Prot. 2008. PMID: 18389709 Free article.
The maximum number of bacteria detected was 6.6 log CFU/g. E. coli prevalence was 47%, and of the positive samples, the mean was 1.9 log CFU/g; counts at the 90th, 95th, and 99th percentiles were 2.3, 2.4, and 2.8 log CFU/g, respectively. The maximum number o …
The maximum number of bacteria detected was 6.6 log CFU/g. E. coli prevalence was 47%, and of the positive samples, the mean was 1.9 …
Phylogenetic affinities of the Fregetta storm-petrels are not black and white.
Robertson BC, Stephenson BM, Ronconi RA, Goldstien SJ, Shepherd L, Tennyson A, Carlile N, Ryan PG. Robertson BC, et al. Mol Phylogenet Evol. 2016 Apr;97:170-176. doi: 10.1016/j.ympev.2016.01.004. Epub 2016 Jan 20. Mol Phylogenet Evol. 2016. PMID: 26804817
We also show that there is greater diversity among F. grallaria populations, with eastern South Pacific F. g. segethi and F. g. titan differing by c. 0.011, and both differing from western South Pacific nominate F. g. grallaria by c. 0.059. The Tristan archip …
We also show that there is greater diversity among F. grallaria populations, with eastern South Pacific F. g. segethi and F. g
Quinobis(imidazolylidene): synthesis and study of an electron-configurable bis(N-heterocyclic carbene) and its bimetallic complexes.
Tennyson AG, Ono RJ, Hudnall TW, Khramov DM, Er JA, Kamplain JW, Lynch VM, Sessler JL, Bielawski CW. Tennyson AG, et al. Chemistry. 2010 Jan 4;16(1):304-15. doi: 10.1002/chem.200901883. Chemistry. 2010. PMID: 19946903
Bimetallic complexes of 1 were prepared by coupling to FcN(3) (2) or FcNCS (3; Fc=ferrocenyl) or coordination to [M(cod)Cl] (4 a or 4 b, where M=Rh or Ir, respectively; cod=1,5-cyclooctadiene). Treatment of 4 a and 4 b with excess CO(g) afforded the correspon …
Bimetallic complexes of 1 were prepared by coupling to FcN(3) (2) or FcNCS (3; Fc=ferrocenyl) or coordination to [M(cod)Cl] (4 a or 4 b
The prevalence and concentration of Bacillus cereus in retail food products in Brisbane, Australia.
Eglezos S, Huang B, Dykes GA, Fegan N. Eglezos S, et al. Foodborne Pathog Dis. 2010 Jul;7(7):867-70. doi: 10.1089/fpd.2009.0469. Foodborne Pathog Dis. 2010. PMID: 20230270
For this reason there is little information on the prevalence and concentration of this pathogen in retail food products. A total of 1263 retail food samples were examined for B. cereus using the Australian Standard 1766.2.6 (1991): spread plate technique on polymyxin pyru …
For this reason there is little information on the prevalence and concentration of this pathogen in retail food products. A total of 1263 re …
Amyloid-β 11C-PiB-PET imaging results from 2 randomized bapineuzumab phase 3 AD trials.
Liu E, Schmidt ME, Margolin R, Sperling R, Koeppe R, Mason NS, Klunk WE, Mathis CA, Salloway S, Fox NC, Hill DL, Les AS, Collins P, Gregg KM, Di J, Lu Y, Tudor IC, Wyman BT, Booth K, Broome S, Yuen E, Grundman M, Brashear HR; Bapineuzumab 301 and 302 Clinical Trial Investigators. Liu E, et al. Neurology. 2015 Aug 25;85(8):692-700. doi: 10.1212/WNL.0000000000001877. Epub 2015 Jul 24. Neurology. 2015. PMID: 26208959 Free PMC article. Clinical Trial.
OBJECTIVE: To evaluate the effects of bapineuzumab on brain beta-amyloid (Abeta) burden using (11)C-Pittsburgh compound B ((11)C-PiB)-PET. METHODS: Two phase 3 clinical trials, 1 each in apolipoprotein APOE epsilon4 carriers and noncarriers, were conducted in patients with …
OBJECTIVE: To evaluate the effects of bapineuzumab on brain beta-amyloid (Abeta) burden using (11)C-Pittsburgh compound B ((11)C-PiB) …
Homozygous familial hypobetalipoproteinemia. Increased LDL catabolism in hypobetalipoproteinemia due to a truncated apolipoprotein B species, apo B-87Padova.
Gabelli C, Bilato C, Martini S, Tennyson GE, Zech LA, Corsini A, Albanese M, Brewer HB Jr, Crepaldi G, Baggio G. Gabelli C, et al. Arterioscler Thromb Vasc Biol. 1996 Sep;16(9):1189-96. doi: 10.1161/01.atv.16.9.1189. Arterioscler Thromb Vasc Biol. 1996. PMID: 8792774
Mutations on the apolipoprotein (apo) B gene that interfere with the full-length translation of the apoB molecule are associated with familial hypobetalipoproteinemia (FHBL), a disease characterized by the reduction of plasma apoB and LDL cholesterol. ...Sequence analysis …
Mutations on the apolipoprotein (apo) B gene that interfere with the full-length translation of the apoB molecule are associated with …
Microbiological quality of wheat grain and flour from two mills in Queensland, Australia.
Eglezos S. Eglezos S. J Food Prot. 2010 Aug;73(8):1533-6. doi: 10.4315/0362-028x-73.8.1533. J Food Prot. 2010. PMID: 20819368 Free article.
The yeast, mold, E. coli, and B. cereus prevalences were 56, 40, 2.0, and 4.0% for grain and 71, 17, 0.7, and <0.3% for flour, respectively. Of the positive samples, the means were 3.7, 2.7, 0.6, and 2.1 for grain, and 3.0, 2.8, and 0.8 log CFU/g for flour. The m …
The yeast, mold, E. coli, and B. cereus prevalences were 56, 40, 2.0, and 4.0% for grain and 71, 17, 0.7, and <0.3% for flour, res …
A survey of the microbiological quality of kangaroo carcasses processed for human consumption in two processing plants in Queensland, Australia.
Eglezos S, Huang B, Stuttard E. Eglezos S, et al. J Food Prot. 2007 May;70(5):1249-51. doi: 10.4315/0362-028x-70.5.1249. J Food Prot. 2007. PMID: 17536688 Free article.
The mean adjusted aerobic plate count (APC) was 2.8 log CFU/g, and counts at the 90th, 95th, and 99th percentiles were 4.2, 4.9, and 6.4 log CFU/g, respectively. The maximum number of bacteria recovered was 6.5 log CFU/g. E. coli was detected in 13.9% of samp …
The mean adjusted aerobic plate count (APC) was 2.8 log CFU/g, and counts at the 90th, 95th, and 99th percentiles were 4.2, 4.9, and …
Exploring extrasolar worlds: from gas giants to terrestrial habitable planets.
Tinetti G, Griffith CA, Swain MR, Deroo P, Beaulieu JP, Vasisht G, Kipping D, Waldmann I, Tennyson J, Barber RJ, Bouwman J, Allard N, Brown LR. Tinetti G, et al. Faraday Discuss. 2010;147:369-77; discussion 379-403. doi: 10.1039/c005126h. Faraday Discuss. 2010. PMID: 21302557
Almost 500 extrasolar planets have been found since the discovery of 51 Peg b by Mayor and Queloz in 1995. The traditional field of planetology has thus expanded its frontiers to include planetary environments not represented in our Solar System. We expect that in the next …
Almost 500 extrasolar planets have been found since the discovery of 51 Peg b by Mayor and Queloz in 1995. The traditional field of p …