Total synthesis of (+/-)-phomactin G, a platelet activating factor antagonist from the marine fungus Phoma sp.
Goldring WP, Pattenden G.
Goldring WP, et al.
Org Biomol Chem. 2004 Feb 21;2(4):466-73. doi: 10.1039/b314816e. Epub 2004 Jan 28.
Org Biomol Chem. 2004.
PMID: 14770224
A total synthesis of phomactin G (), which is a central intermediate in the biosynthesis of phomactin A () in Phoma sp. is described. The synthesis is based on a Cr(ii)/Ni(ii) macrocyclisation from the aldehyde vinyl iodide, leading to, followed by sequential conversion of …
A total synthesis of phomactin G (), which is a central intermediate in the biosynthesis of phomactin A () in Phoma sp. is described. …