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Page 1
Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk.
Das Pradhan A, Glynn RJ, Fruchart JC, MacFadyen JG, Zaharris ES, Everett BM, Campbell SE, Oshima R, Amarenco P, Blom DJ, Brinton EA, Eckel RH, Elam MB, Felicio JS, Ginsberg HN, Goudev A, Ishibashi S, Joseph J, Kodama T, Koenig W, Leiter LA, Lorenzatti AJ, Mankovsky B, Marx N, Nordestgaard BG, Páll D, Ray KK, Santos RD, Soran H, Susekov A, Tendera M, Yokote K, Paynter NP, Buring JE, Libby P, Ridker PM; PROMINENT Investigators. Das Pradhan A, et al. N Engl J Med. 2022 Nov 24;387(21):1923-1934. doi: 10.1056/NEJMoa2210645. Epub 2022 Nov 5. N Engl J Med. 2022. PMID: 36342113 Clinical Trial.
Infant Formula With a Specific Blend of Five Human Milk Oligosaccharides Drives the Gut Microbiota Development and Improves Gut Maturation Markers: A Randomized Controlled Trial.
Bosheva M, Tokodi I, Krasnow A, Pedersen HK, Lukjancenko O, Eklund AC, Grathwohl D, Sprenger N, Berger B, Cercamondi CI; 5 HMO Study Investigator Consortium. Bosheva M, et al. Front Nutr. 2022 Jul 6;9:920362. doi: 10.3389/fnut.2022.920362. eCollection 2022. Front Nutr. 2022. PMID: 35873420 Free PMC article.
METHODS: In a multicenter study, healthy infants (7-21 days old) were randomly assigned to a standard cow's milk-based infant formula (control group, CG); the same formula with 1.5 g/L HMOs (test group 1, TG1); or with 2.5 g/L HMOs (test group 2, TG2). A human milk- …
METHODS: In a multicenter study, healthy infants (7-21 days old) were randomly assigned to a standard cow's milk-based infant formula (contr …
Heparanase-1: From Cancer Biology to a Future Antiviral Target.
Lebsir N, Zoulim F, Grigorov B. Lebsir N, et al. Viruses. 2023 Jan 14;15(1):237. doi: 10.3390/v15010237. Viruses. 2023. PMID: 36680276 Free PMC article. Review.
Interestingly, heparanase-1 has also been documented to be involved in numerous viral infections, e.g., HSV-1, HPV, DENV. Moreover, very recent reports have demonstrated a role of heparanase-1 in HCV and SARS-CoV-2 infections. ...
Interestingly, heparanase-1 has also been documented to be involved in numerous viral infections, e.g., HSV-1, HPV, DENV. Moreover, v …
Computational studies of ligand-receptor interactions in bitter taste receptors.
Miguet L, Zhang Z, Grigorov MG. Miguet L, et al. J Recept Signal Transduct Res. 2006;26(5-6):611-30. doi: 10.1080/10799890600928210. J Recept Signal Transduct Res. 2006. PMID: 17118801
Recently, it was suggested that phenylthiocarbamide elicits bitter taste by interacting with a human G protein-coupled receptor (hTAS2R38) encoded by the PTC gene. The phenylthiocarbamide nontaster trait was linked to three single nucleotide polymorphisms occurring in the …
Recently, it was suggested that phenylthiocarbamide elicits bitter taste by interacting with a human G protein-coupled receptor (hTAS …
Catalase inhibition in diabetic rats potentiates DNA damage and apoptotic cell death setting the stage for cardiomyopathy.
Ivanović-Matić S, Bogojević D, Martinović V, Petrović A, Jovanović-Stojanov S, Poznanović G, Grigorov I. Ivanović-Matić S, et al. J Physiol Biochem. 2014 Dec;70(4):947-59. doi: 10.1007/s13105-014-0363-y. Epub 2014 Oct 9. J Physiol Biochem. 2014. PMID: 25298180
Thus, in the present work, we examined the effects of the daily administration of the CAT inhibitor, 3-amino-1,2,4-triazole (1 mg/g), on the hearts of streptozotocin (STZ)-induced diabetic rats. Administration of CAT inhibitor was started from the 15th day after the last S …
Thus, in the present work, we examined the effects of the daily administration of the CAT inhibitor, 3-amino-1,2,4-triazole (1 mg/g), …
The protective role of virgin coconut oil on the alloxan-induced oxidative stress in the liver, kidneys and heart of diabetic rats.
Đurašević S, Jasnić N, Prokić M, Grigorov I, Martinović V, Đorđević J, Pavlović S. Đurašević S, et al. Food Funct. 2019 Apr 1;10(4):2114-2124. doi: 10.1039/c9fo00107g. Epub 2019 Mar 28. Food Funct. 2019. PMID: 30919867
VCO reduced the diabetes-related increase in food (82.15 1.49 vs. 145.51 4.81 g per kg b.m. per day) and water (305.49 6.09 vs. 583.98 14.80 mL per kg b.m. per day) intake, and the decrease in the body mass gain (0.56 0.16 vs. -2.13 0.49 g per 100 g …
VCO reduced the diabetes-related increase in food (82.15 1.49 vs. 145.51 4.81 g per kg b.m. per day) and water (305.49 6.09 vs. …
Correlates of cognitive status of old patients with isolated systolic hypertension: the Syst-Eur Vascular Dementia Project.
Seux ML, Thijs L, Forette F, Staessen JA, Birkenhäger WH, Bulpitt CJ, Girerd X, Jääskivi M, Vanhanen H, Kivinen P, Yodfat Y, Vänskä O, Antikainen R, Laks T, Webster JR, Hakamäki T, Lehtomäki E, Lilov E, Grigorov M, Janculova K, Halonen K, Kohonen-Jalonen P, Kermowa R, Nachev C, Tuomilehto J. Seux ML, et al. J Hypertens. 1998 Jul;16(7):963-9. doi: 10.1097/00004872-199816070-00009. J Hypertens. 1998. PMID: 9794736 Clinical Trial.
Men and women who consumed alcohol (28%) had median intakes of 8 and 3 g/day, respectively. The median MMSE score was 29 (range 15-30). The maximum score of 30 was attained by 609 (30%) subjects. ...
Men and women who consumed alcohol (28%) had median intakes of 8 and 3 g/day, respectively. The median MMSE score was 29 (range 15-30 …
Treatment of anemia with darbepoetin alfa in systolic heart failure.
Swedberg K, Young JB, Anand IS, Cheng S, Desai AS, Diaz R, Maggioni AP, McMurray JJ, O'Connor C, Pfeffer MA, Solomon SD, Sun Y, Tendera M, van Veldhuisen DJ; RED-HF Committees; RED-HF Investigators. Swedberg K, et al. N Engl J Med. 2013 Mar 28;368(13):1210-9. doi: 10.1056/NEJMoa1214865. Epub 2013 Mar 10. N Engl J Med. 2013. PMID: 23473338 Free article. Clinical Trial.
METHODS: In this randomized, double-blind trial, we assigned 2278 patients with systolic heart failure and mild-to-moderate anemia (hemoglobin level, 9.0 to 12.0 g per deciliter) to receive either darbepoetin alfa (to achieve a hemoglobin target of 13 g per decilite …
METHODS: In this randomized, double-blind trial, we assigned 2278 patients with systolic heart failure and mild-to-moderate anemia (hemoglob …
24 results