Search Page

1

Cite

Share

Delineating biased ligand efficacy at 7TM receptors from an experimental perspective.

Galandrin S, Onfroy L, Poirot MC, Sénard JM, Galés C. Galandrin S, et al. Int J Biochem Cell Biol. 2016 Aug;77(Pt B):251-63. doi: 10.1016/j.biocel.2016.04.009. Epub 2016 Apr 21. Int J Biochem Cell Biol. 2016. PMID: 27107932 Review.

Cite

Share

2

Cite

Share

Probing heterotrimeric G protein activation: applications to biased ligands.

Denis C, Saulière A, Galandrin S, Sénard JM, Galés C. Denis C, et al. Among authors: galandrin s. Curr Pharm Des. 2012;18(2):128-44. doi: 10.2174/138161212799040466. Curr Pharm Des. 2012. PMID: 22229559 Free PMC article. Review.

Cite

Share

3

Cite

Share

The evasive nature of drug efficacy: implications for drug discovery.

Galandrin S, Oligny-Longpré G, Bouvier M. Galandrin S, et al. Trends Pharmacol Sci. 2007 Aug;28(8):423-30. doi: 10.1016/j.tips.2007.06.005. Epub 2007 Jul 19. Trends Pharmacol Sci. 2007. PMID: 17659355 Review.

Cite

Share

4

Cite

Share

G protein stoichiometry dictates biased agonism through distinct receptor-G protein partitioning.

Onfroy L, Galandrin S, Pontier SM, Seguelas MH, N'Guyen D, Sénard JM, Galés C. Onfroy L, et al. Among authors: galandrin s. Sci Rep. 2017 Aug 11;7(1):7885. doi: 10.1038/s41598-017-07392-5. Sci Rep. 2017. PMID: 28801617 Free PMC article.

Cite

Share

5

Cite

Share

The experimental power of FR900359 to study Gq-regulated biological processes.

Schrage R, Schmitz AL, Gaffal E, Annala S, Kehraus S, Wenzel D, Büllesbach KM, Bald T, Inoue A, Shinjo Y, Galandrin S, Shridhar N, Hesse M, Grundmann M, Merten N, Charpentier TH, Martz M, Butcher AJ, Slodczyk T, Armando S, Effern M, Namkung Y, Jenkins L, Horn V, Stößel A, Dargatz H, Tietze D, Imhof D, Galés C, Drewke C, Müller CE, Hölzel M, Milligan G, Tobin AB, Gomeza J, Dohlman HG, Sondek J, Harden TK, Bouvier M, Laporte SA, Aoki J, Fleischmann BK, Mohr K, König GM, Tüting T, Kostenis E. Schrage R, et al. Among authors: galandrin s. Nat Commun. 2015 Dec 14;6:10156. doi: 10.1038/ncomms10156. Nat Commun. 2015. PMID: 26658454 Free PMC article.

Cite

Share

6

Cite

Share

Dual agonist occupancy of AT1-R-α2C-AR heterodimers results in atypical Gs-PKA signaling.

Bellot M, Galandrin S, Boularan C, Matthies HJ, Despas F, Denis C, Javitch J, Mazères S, Sanni SJ, Pons V, Seguelas MH, Hansen JL, Pathak A, Galli A, Sénard JM, Galés C. Bellot M, et al. Among authors: galandrin s. Nat Chem Biol. 2015 Apr;11(4):271-9. doi: 10.1038/nchembio.1766. Epub 2015 Feb 23. Nat Chem Biol. 2015. PMID: 25706338 Free PMC article.

Cite

Share

7

Cite

Share

Insight into Structure-Function Relationships and Inhibition of the Fatty Acyl-AMP Ligase (FadD32) Orthologs from Mycobacteria.

Guillet V, Galandrin S, Maveyraud L, Ladevèze S, Mariaule V, Bon C, Eynard N, Daffé M, Marrakchi H, Mourey L. Guillet V, et al. Among authors: galandrin s. J Biol Chem. 2016 Apr 8;291(15):7973-89. doi: 10.1074/jbc.M115.712612. Epub 2016 Feb 21. J Biol Chem. 2016. PMID: 26900152 Free PMC article.

Cite

Share

8

Cite

Share

Assay development for identifying inhibitors of the mycobacterial FadD32 activity.

Galandrin S, Guillet V, Rane RS, Léger M, N R, Eynard N, Das K, Balganesh TS, Mourey L, Daffé M, Marrakchi H. Galandrin S, et al. J Biomol Screen. 2013 Jun;18(5):576-87. doi: 10.1177/1087057112474691. Epub 2013 Jan 30. J Biomol Screen. 2013. PMID: 23364516

Cite

Share

9

Cite

Share

Cardioprotective Angiotensin-(1-7) Peptide Acts as a Natural-Biased Ligand at the Angiotensin II Type 1 Receptor.

Galandrin S, Denis C, Boularan C, Marie J, M'Kadmi C, Pilette C, Dubroca C, Nicaise Y, Seguelas MH, N'Guyen D, Banères JL, Pathak A, Sénard JM, Galés C. Galandrin S, et al. Hypertension. 2016 Dec;68(6):1365-1374. doi: 10.1161/HYPERTENSIONAHA.116.08118. Epub 2016 Oct 3. Hypertension. 2016. PMID: 27698068

Cite

Share

10

Cite

Share

Ghrelin receptor conformational dynamics regulate the transition from a preassembled to an active receptor:Gq complex.

Damian M, Mary S, Maingot M, M'Kadmi C, Gagne D, Leyris JP, Denoyelle S, Gaibelet G, Gavara L, Garcia de Souza Costa M, Perahia D, Trinquet E, Mouillac B, Galandrin S, Galès C, Fehrentz JA, Floquet N, Martinez J, Marie J, Banères JL. Damian M, et al. Among authors: galandrin s. Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):1601-6. doi: 10.1073/pnas.1414618112. Epub 2015 Jan 20. Proc Natl Acad Sci U S A. 2015. PMID: 25605885 Free PMC article.

Cite

Share