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Recapitulating idiopathic pulmonary fibrosis related alveolar epithelial dysfunction in a human iPSC-derived air-liquid interface model.

Schruf E, Schroeder V, Le HQ, Schönberger T, Raedel D, Stewart EL, Fundel-Clemens K, Bluhmki T, Weigle S, Schuler M, Thomas MJ, Heilker R, Webster MJ, Dass M, Frick M, Stierstorfer B, Quast K, Garnett JP. Schruf E, et al. Among authors: garnett jp. FASEB J. 2020 Jun;34(6):7825-7846. doi: 10.1096/fj.201902926R. Epub 2020 Apr 16. FASEB J. 2020. PMID: 32297676

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Human lung fibroblast-to-myofibroblast transformation is not driven by an LDH5-dependent metabolic shift towards aerobic glycolysis.

Schruf E, Schroeder V, Kuttruff CA, Weigle S, Krell M, Benz M, Bretschneider T, Holweg A, Schuler M, Frick M, Nicklin P, Garnett JP, Sobotta MC. Schruf E, et al. Among authors: garnett jp. Respir Res. 2019 May 9;20(1):87. doi: 10.1186/s12931-019-1058-2. Respir Res. 2019. PMID: 31072408 Free PMC article.

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Effective glucose metabolism maintains low intracellular glucose in airway epithelial cells after exposure to hyperglycemia.

Bearham J, Garnett JP, Schroeder V, Biggart MGS, Baines DL. Bearham J, et al. Among authors: garnett jp. Am J Physiol Cell Physiol. 2019 Nov 1;317(5):C983-C992. doi: 10.1152/ajpcell.00193.2019. Epub 2019 Aug 21. Am J Physiol Cell Physiol. 2019. PMID: 31433692 Free PMC article.

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Real-time measurement of cellular bioenergetics in fully differentiated human nasal epithelial cells grown at air-liquid-interface.

Mavin E, Verdon B, Carrie S, Saint-Criq V, Powell J, Kuttruff CA, Ward C, Garnett JP, Miwa S. Mavin E, et al. Among authors: garnett jp. Am J Physiol Lung Cell Mol Physiol. 2020 Jun 1;318(6):L1158-L1164. doi: 10.1152/ajplung.00414.2019. Epub 2020 Apr 8. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 32267720 Free PMC article.

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Real-Time, Semi-Automated Fluorescent Measurement of the Airway Surface Liquid pH of Primary Human Airway Epithelial Cells.

Saint-Criq V, Haq IJ, Gardner AI, Garnett JP, Ward C, Brodlie M, Gray MA. Saint-Criq V, et al. Among authors: garnett jp. J Vis Exp. 2019 Jun 13;(148):10.3791/59815. doi: 10.3791/59815. J Vis Exp. 2019. PMID: 31259916 Free PMC article.

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E-cigarette constituents propylene glycol and vegetable glycerin decrease glucose uptake and its metabolism in airway epithelial cells in vitro.

Woodall M, Jacob J, Kalsi KK, Schroeder V, Davis E, Kenyon B, Khan I, Garnett JP, Tarran R, Baines DL. Woodall M, et al. Among authors: garnett jp. Am J Physiol Lung Cell Mol Physiol. 2020 Dec 1;319(6):L957-L967. doi: 10.1152/ajplung.00123.2020. Epub 2020 Sep 30. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 32996783 Free PMC article.

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Airway surface liquid homeostasis in cystic fibrosis: pathophysiology and therapeutic targets.

Haq IJ, Gray MA, Garnett JP, Ward C, Brodlie M. Haq IJ, et al. Among authors: garnett jp. Thorax. 2016 Mar;71(3):284-7. doi: 10.1136/thoraxjnl-2015-207588. Epub 2015 Dec 30. Thorax. 2016. PMID: 26719229 Review.

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Excess Mucin Impairs Subglottic Epithelial Host Defense in Mechanically Ventilated Patients.

Powell J, Garnett JP, Mather MW, Cooles FAH, Nelson A, Verdon B, Scott J, Jiwa K, Ruchaud-Sparagano MH, Cummings SP, Perry JD, Wright SE, Wilson JA, Pearson J, Ward C, Simpson AJ. Powell J, et al. Among authors: garnett jp. Am J Respir Crit Care Med. 2018 Aug 1;198(3):340-349. doi: 10.1164/rccm.201709-1819OC. Am J Respir Crit Care Med. 2018. PMID: 29425465

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Increased airway glucose increases airway bacterial load in hyperglycaemia.

Gill SK, Hui K, Farne H, Garnett JP, Baines DL, Moore LS, Holmes AH, Filloux A, Tregoning JS. Gill SK, et al. Among authors: garnett jp. Sci Rep. 2016 Jun 8;6:27636. doi: 10.1038/srep27636. Sci Rep. 2016. PMID: 27273266 Free PMC article.

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Sweet talk: insights into the nature and importance of glucose transport in lung epithelium.

Garnett JP, Baker EH, Baines DL. Garnett JP, et al. Eur Respir J. 2012 Nov;40(5):1269-76. doi: 10.1183/09031936.00052612. Epub 2012 Aug 9. Eur Respir J. 2012. PMID: 22878875 Free article. Review.

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