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Yoda1 analogue (Dooku1) which antagonizes Yoda1-evoked activation of Piezo1 and aortic relaxation.

Evans EL, Cuthbertson K, Endesh N, Rode B, Blythe NM, Hyman AJ, Hall SJ, Gaunt HJ, Ludlow MJ, Foster R, Beech DJ. Evans EL, et al. Among authors: gaunt hj. Br J Pharmacol. 2018 May;175(10):1744-1759. doi: 10.1111/bph.14188. Epub 2018 Apr 6. Br J Pharmacol. 2018. PMID: 29498036 Free PMC article.

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Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performance.

Rode B, Shi J, Endesh N, Drinkhill MJ, Webster PJ, Lotteau SJ, Bailey MA, Yuldasheva NY, Ludlow MJ, Cubbon RM, Li J, Futers TS, Morley L, Gaunt HJ, Marszalek K, Viswambharan H, Cuthbertson K, Baxter PD, Foster R, Sukumar P, Weightman A, Calaghan SC, Wheatcroft SB, Kearney MT, Beech DJ. Rode B, et al. Among authors: gaunt hj. Nat Commun. 2017 Aug 24;8(1):350. doi: 10.1038/s41467-017-00429-3. Nat Commun. 2017. PMID: 28839146 Free PMC article.

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Rab46 integrates Ca²⁺ and histamine signaling to regulate selective cargo release from Weibel-Palade bodies.

Miteva KT, Pedicini L, Wilson LA, Jayasinghe I, Slip RG, Marszalek K, Gaunt HJ, Bartoli F, Deivasigamani S, Sobradillo D, Beech DJ, McKeown L. Miteva KT, et al. Among authors: gaunt hj. J Cell Biol. 2019 Jul 1;218(7):2232-2246. doi: 10.1083/jcb.201810118. Epub 2019 May 15. J Cell Biol. 2019. PMID: 31092558 Free PMC article.

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Pilot Study: Thinking Outside the Square in Cultivating "Soft Skills"-Going beyond the Standard Optometric Curriculum.

Cham KM, Gaunt H, Delany C. Cham KM, et al. Among authors: gaunt h. Optom Vis Sci. 2020 Nov;97(11):962-969. doi: 10.1097/OPX.0000000000001594. Optom Vis Sci. 2020. PMID: 33110021

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Clinical outcomes of patients discharged from the Rapid Access Chest Pain Clinic with non-anginal chest pain: A retrospective cohort study.

Kite TA, Gaunt H, Banning AS, Roberts E, Kovac J, Hudson I, Gershlick AH. Kite TA, et al. Among authors: gaunt h. Int J Cardiol. 2020 Mar 1;302:1-4. doi: 10.1016/j.ijcard.2019.12.008. Epub 2019 Dec 6. Int J Cardiol. 2020. PMID: 31864788

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Piezo1 channels are mechanosensors in human fetoplacental endothelial cells.

Morley LC, Shi J, Gaunt HJ, Hyman AJ, Webster PJ, Williams C, Forbes K, Walker JJ, Simpson NAB, Beech DJ. Morley LC, et al. Among authors: gaunt hj. Mol Hum Reprod. 2018 Oct 1;24(10):510-520. doi: 10.1093/molehr/gay033. Mol Hum Reprod. 2018. PMID: 30085186 Free PMC article.

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Homotypic endothelial nanotubes induced by wheat germ agglutinin and thrombin.

Pedicini L, Miteva KT, Hawley V, Gaunt HJ, Appleby HL, Cubbon RM, Marszalek K, Kearney MT, Beech DJ, McKeown L. Pedicini L, et al. Among authors: gaunt hj. Sci Rep. 2018 May 15;8(1):7569. doi: 10.1038/s41598-018-25853-3. Sci Rep. 2018. PMID: 29765077 Free PMC article.

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Transient receptor potential canonical 4 and 5 proteins as targets in cancer therapeutics.

Gaunt HJ, Vasudev NS, Beech DJ. Gaunt HJ, et al. Eur Biophys J. 2016 Oct;45(7):611-620. doi: 10.1007/s00249-016-1142-1. Epub 2016 Jun 11. Eur Biophys J. 2016. PMID: 27289383 Free PMC article. Review.

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Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels.

Rubaiy HN, Ludlow MJ, Henrot M, Gaunt HJ, Miteva K, Cheung SY, Tanahashi Y, Hamzah N, Musialowski KE, Blythe NM, Appleby HL, Bailey MA, McKeown L, Taylor R, Foster R, Waldmann H, Nussbaumer P, Christmann M, Bon RS, Muraki K, Beech DJ. Rubaiy HN, et al. Among authors: gaunt hj. J Biol Chem. 2017 May 19;292(20):8158-8173. doi: 10.1074/jbc.M116.773556. Epub 2017 Mar 21. J Biol Chem. 2017. PMID: 28325835 Free PMC article.

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Natural and synthetic flavonoid modulation of TRPC5 channels.

Naylor J, Minard A, Gaunt HJ, Amer MS, Wilson LA, Migliore M, Cheung SY, Rubaiy HN, Blythe NM, Musialowski KE, Ludlow MJ, Evans WD, Green BL, Yang H, You Y, Li J, Fishwick CW, Muraki K, Beech DJ, Bon RS. Naylor J, et al. Among authors: gaunt hj. Br J Pharmacol. 2016 Feb;173(3):562-74. doi: 10.1111/bph.13387. Epub 2016 Jan 13. Br J Pharmacol. 2016. PMID: 26565375 Free PMC article.

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