Generaux GT[au] - Search Results

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Year	Number of Results
2008	1
2009	1
2010	1
2011	2
2012	1
2013	2
2017	1
2022	0

Page 1

Impact of SLCO1B1 (OATP1B1) and ABCG2 (BCRP) genetic polymorphisms and inhibition on LDL-C lowering and myopathy of statins.

Generaux GT, Bonomo FM, Johnson M, Doan KM. Generaux GT, et al. Xenobiotica. 2011 Aug;41(8):639-51. doi: 10.3109/00498254.2011.562566. Epub 2011 Mar 22. Xenobiotica. 2011. PMID: 21425956 Review.

Impact of physiologically based pharmacokinetic modeling and simulation in drug development.

Shardlow CE, Generaux GT, Patel AH, Tai G, Tran T, Bloomer JC. Shardlow CE, et al. Among authors: generaux gt. Drug Metab Dispos. 2013 Dec;41(12):1994-2003. doi: 10.1124/dmd.113.052803. Epub 2013 Sep 5. Drug Metab Dispos. 2013. PMID: 24009310

An in vitro mechanistic study to elucidate the desipramine/bupropion clinical drug-drug interaction.

Reese MJ, Wurm RM, Muir KT, Generaux GT, St John-Williams L, McConn DJ. Reese MJ, et al. Among authors: generaux gt. Drug Metab Dispos. 2008 Jul;36(7):1198-201. doi: 10.1124/dmd.107.020198. Epub 2008 Apr 17. Drug Metab Dispos. 2008. PMID: 18420781

Utilizing drug-drug interaction prediction tools during drug development: enhanced decision making based on clinical risk.

Shardlow CE, Generaux GT, MacLauchlin CC, Pons N, Skordos KW, Bloomer JC. Shardlow CE, et al. Among authors: generaux gt. Drug Metab Dispos. 2011 Nov;39(11):2076-84. doi: 10.1124/dmd.111.039214. Epub 2011 Aug 10. Drug Metab Dispos. 2011. PMID: 21832001

In vitro investigations into the roles of drug transporters and metabolizing enzymes in the disposition and drug interactions of dolutegravir, a HIV integrase inhibitor.

Reese MJ, Savina PM, Generaux GT, Tracey H, Humphreys JE, Kanaoka E, Webster LO, Harmon KA, Clarke JD, Polli JW. Reese MJ, et al. Among authors: generaux gt. Drug Metab Dispos. 2013 Feb;41(2):353-61. doi: 10.1124/dmd.112.048918. Epub 2012 Nov 6. Drug Metab Dispos. 2013. PMID: 23132334

Use of cassette dosing in sandwich-cultured rat and human hepatocytes to identify drugs that inhibit bile acid transport.

Wolf KK, Vora S, Webster LO, Generaux GT, Polli JW, Brouwer KL. Wolf KK, et al. Among authors: generaux gt. Toxicol In Vitro. 2010 Feb;24(1):297-309. doi: 10.1016/j.tiv.2009.08.009. Epub 2009 Aug 23. Toxicol In Vitro. 2010. PMID: 19706322 Free PMC article.

Refining Liver Safety Risk Assessment: Application of Mechanistic Modeling and Serum Biomarkers to Cimaglermin Alfa (GGF2) Clinical Trials.

Longo DM, Generaux GT, Howell BA, Siler SQ, Antoine DJ, Button D, Caggiano A, Eisen A, Iaci J, Stanulis R, Parry T, Mosedale M, Watkins PB. Longo DM, et al. Among authors: generaux gt. Clin Pharmacol Ther. 2017 Dec;102(6):961-969. doi: 10.1002/cpt.711. Epub 2017 May 27. Clin Pharmacol Ther. 2017. PMID: 28419467 Free PMC article.

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