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lentiMPRA and MPRAflow for high-throughput functional characterization of gene regulatory elements.
Gordon MG, Inoue F, Martin B, Schubach M, Agarwal V, Whalen S, Feng S, Zhao J, Ashuach T, Ziffra R, Kreimer A, Georgakopoulos-Soares I, Yosef N, Ye CJ, Pollard KS, Shendure J, Kircher M, Ahituv N. Gordon MG, et al. Among authors: georgakopoulos soares i. Nat Protoc. 2020 Aug;15(8):2387-2412. doi: 10.1038/s41596-020-0333-5. Epub 2020 Jul 8. Nat Protoc. 2020. PMID: 32641802 Free PMC article.
Characterizing Mutational Signatures in Human Cancer Cell Lines Reveals Episodic APOBEC Mutagenesis.
Petljak M, Alexandrov LB, Brammeld JS, Price S, Wedge DC, Grossmann S, Dawson KJ, Ju YS, Iorio F, Tubio JMC, Koh CC, Georgakopoulos-Soares I, Rodríguez-Martín B, Otlu B, O'Meara S, Butler AP, Menzies A, Bhosle SG, Raine K, Jones DR, Teague JW, Beal K, Latimer C, O'Neill L, Zamora J, Anderson E, Patel N, Maddison M, Ng BL, Graham J, Garnett MJ, McDermott U, Nik-Zainal S, Campbell PJ, Stratton MR. Petljak M, et al. Among authors: georgakopoulos soares i. Cell. 2019 Mar 7;176(6):1282-1294.e20. doi: 10.1016/j.cell.2019.02.012. Cell. 2019. PMID: 30849372 Free PMC article.
Approaches of dengue control: vaccine strategies and future aspects.
Akter R, Tasneem F, Das S, Soma MA, Georgakopoulos-Soares I, Juthi RT, Sazed SA. Akter R, et al. Among authors: georgakopoulos soares i. Front Immunol. 2024 Feb 29;15:1362780. doi: 10.3389/fimmu.2024.1362780. eCollection 2024. Front Immunol. 2024. PMID: 38487527 Free PMC article. Review.
Alternative splicing modulation by G-quadruplexes.
Georgakopoulos-Soares I, Parada GE, Wong HY, Medhi R, Furlan G, Munita R, Miska EA, Kwok CK, Hemberg M. Georgakopoulos-Soares I, et al. Nat Commun. 2022 May 3;13(1):2404. doi: 10.1038/s41467-022-30071-7. Nat Commun. 2022. PMID: 35504902 Free PMC article.
Strand asymmetries across genomic processes.
Moeckel C, Zaravinos A, Georgakopoulos-Soares I. Moeckel C, et al. Among authors: georgakopoulos soares i. Comput Struct Biotechnol J. 2023 Mar 11;21:2036-2047. doi: 10.1016/j.csbj.2023.03.007. eCollection 2023. Comput Struct Biotechnol J. 2023. PMID: 36968020 Free PMC article. Review.
Editorial: Mutational signatures and immune response in cancer.
Georgakopoulos-Soares I, Zaravinos A. Georgakopoulos-Soares I, et al. Front Genet. 2023 May 17;14:1215326. doi: 10.3389/fgene.2023.1215326. eCollection 2023. Front Genet. 2023. PMID: 37265964 Free PMC article. No abstract available.
Visualizing metagenomic and metatranscriptomic data: A comprehensive review.
Aplakidou E, Vergoulidis N, Chasapi M, Venetsianou NK, Kokoli M, Panagiotopoulou E, Iliopoulos I, Karatzas E, Pafilis E, Georgakopoulos-Soares I, Kyrpides NC, Pavlopoulos GA, Baltoumas FA. Aplakidou E, et al. Among authors: georgakopoulos soares i. Comput Struct Biotechnol J. 2024 May 3;23:2011-2033. doi: 10.1016/j.csbj.2024.04.060. eCollection 2024 Dec. Comput Struct Biotechnol J. 2024. PMID: 38765606 Free PMC article. Review.
The chemotherapeutic drug CX-5461 is a potent mutagen in cultured human cells.
Koh GCC, Boushaki S, Zhao SJ, Pregnall AM, Sadiyah F, Badja C, Memari Y, Georgakopoulos-Soares I, Nik-Zainal S. Koh GCC, et al. Among authors: georgakopoulos soares i. Nat Genet. 2024 Jan;56(1):23-26. doi: 10.1038/s41588-023-01602-9. Epub 2023 Nov 30. Nat Genet. 2024. PMID: 38036782 Free PMC article.
Secondary structures in RNA synthesis, splicing and translation.
Georgakopoulos-Soares I, Parada GE, Hemberg M. Georgakopoulos-Soares I, et al. Comput Struct Biotechnol J. 2022 May 27;20:2871-2884. doi: 10.1016/j.csbj.2022.05.041. eCollection 2022. Comput Struct Biotechnol J. 2022. PMID: 35765654 Free PMC article. Review.
MPRAbase: A Massively Parallel Reporter Assay Database.
Zhao J, Baltoumas FA, Konnaris MA, Mouratidis I, Liu Z, Sims J, Agarwal V, Pavlopoulos GA, Georgakopoulos-Soares I, Ahituv N. Zhao J, et al. Among authors: georgakopoulos soares i. bioRxiv [Preprint]. 2023 Nov 22:2023.11.19.567742. doi: 10.1101/2023.11.19.567742. bioRxiv. 2023. PMID: 38045264 Free PMC article. Preprint.
52 results