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1995 2
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2014 1
2019 1
2020 2
2021 1
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A fully human anti-BMP6 antibody reduces the need for erythropoietin in rodent models of the anemia of chronic disease.
Petzer V, Tymoszuk P, Asshoff M, Carvalho J, Papworth J, Deantonio C, Bayliss L, Wake MS, Seifert M, Brigo N, Valente de Souza L, Hilbe R, Grubwieser P, Demetz E, Dichtl S, Volani C, Berger S, Böhm F, Hoffmann A, Pfeifhofer-Obermair C, von Raffay L, Sopper S, Arndt S, Bosserhoff A, Kautz L, Perrier P, Nairz M, Wolf D, Weiss G, Germaschewski V, Theurl I. Petzer V, et al. Among authors: germaschewski v. Blood. 2020 Aug 27;136(9):1080-1090. doi: 10.1182/blood.2019004653. Blood. 2020. PMID: 32438400 Free PMC article.
Complete humanization of the mouse immunoglobulin loci enables efficient therapeutic antibody discovery.
Lee EC, Liang Q, Ali H, Bayliss L, Beasley A, Bloomfield-Gerdes T, Bonoli L, Brown R, Campbell J, Carpenter A, Chalk S, Davis A, England N, Fane-Dremucheva A, Franz B, Germaschewski V, Holmes H, Holmes S, Kirby I, Kosmac M, Legent A, Lui H, Manin A, O'Leary S, Paterson J, Sciarrillo R, Speak A, Spensberger D, Tuffery L, Waddell N, Wang W, Wells S, Wong V, Wood A, Owen MJ, Friedrich GA, Bradley A. Lee EC, et al. Among authors: germaschewski v. Nat Biotechnol. 2014 Apr;32(4):356-63. doi: 10.1038/nbt.2825. Epub 2014 Mar 16. Nat Biotechnol. 2014. PMID: 24633243
A therapeutic antibody targeting osteoprotegerin attenuates severe experimental pulmonary arterial hypertension.
Arnold ND, Pickworth JA, West LE, Dawson S, Carvalho JA, Casbolt H, Braithwaite AT, Iremonger J, Renshall L, Germaschewski V, McCourt M, Bland-Ward P, Kowash H, Hameed AG, Rothman AMK, Frid MG, Roger Thompson AA, Evans HR, Southwood M, Morrell NW, Crossman DC, Whyte MKB, Stenmark KR, Newman CM, Kiely DG, Francis SE, Lawrie A. Arnold ND, et al. Among authors: germaschewski v. Nat Commun. 2019 Nov 15;10(1):5183. doi: 10.1038/s41467-019-13139-9. Nat Commun. 2019. PMID: 31729368 Free PMC article.
An Antibody Targeting ICOS Increases Intratumoral Cytotoxic to Regulatory T-cell Ratio and Induces Tumor Regression.
Sainson RCA, Thotakura AK, Kosmac M, Borhis G, Parveen N, Kimber R, Carvalho J, Henderson SJ, Pryke KL, Okell T, O'Leary S, Ball S, Van Krinks C, Gamand L, Taggart E, Pring EJ, Ali H, Craig H, Wong VWY, Liang Q, Rowlands RJ, Lecointre M, Campbell J, Kirby I, Melvin D, Germaschewski V, Oelmann E, Quaratino S, McCourt M. Sainson RCA, et al. Among authors: germaschewski v. Cancer Immunol Res. 2020 Dec;8(12):1568-1582. doi: 10.1158/2326-6066.CIR-20-0034. Epub 2020 Sep 30. Cancer Immunol Res. 2020. PMID: 32999002 Free article.
Systemic administration of Abeta mAb reduces retinal deposition of Abeta and activated complement C3 in age-related macular degeneration mouse model.
Catchpole I, Germaschewski V, Hoh Kam J, Lundh von Leithner P, Ford S, Gough G, Adamson P, Overend P, Hilpert J, López FJ, Ng YS, Coffey P, Jeffery G. Catchpole I, et al. Among authors: germaschewski v. PLoS One. 2013 Jun 14;8(6):e65518. doi: 10.1371/journal.pone.0065518. Print 2013. PLoS One. 2013. PMID: 23799019 Free PMC article.
Pragmatic mAb lead molecule engineering from a developability perspective.
Chi B, De Oliveira G, Gallagher T, Mitchell L, Knightley L, Gonzalez CC, Russell S, Germaschewski V, Pearce C, Sellick CA. Chi B, et al. Among authors: germaschewski v. Biotechnol Bioeng. 2021 Apr 29. doi: 10.1002/bit.27802. Online ahead of print. Biotechnol Bioeng. 2021. PMID: 33913507