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1959 2
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70,095 results

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The following term was not found in PubMed: Poursharafodin
Page 1
Musculoskeletal Effects of Altered GH Action.
Young JA, Zhu S, List EO, Duran-Ortiz S, Slama Y, Berryman DE. Young JA, et al. Front Physiol. 2022 May 19;13:867921. doi: 10.3389/fphys.2022.867921. eCollection 2022. Front Physiol. 2022. PMID: 35665221 Free PMC article. Review.
In addition to its metabolic and musculoskeletal effects, GH is closely associated with aging, with levels declining as individuals age but GH action negatively correlating with lifespan. GH's effects have been studied in human conditions of GH alterat …
In addition to its metabolic and musculoskeletal effects, GH is closely associated with aging, with levels declining as individuals a …
Genetic disorders of GH action pathway.
Domené HM, Fierro-Carrión G. Domené HM, et al. Growth Horm IGF Res. 2018 Feb;38:19-23. doi: 10.1016/j.ghir.2017.12.004. Epub 2017 Dec 12. Growth Horm IGF Res. 2018. PMID: 29249625 Review.
While insensitivity to GH (GHI) is characterized by low IGF-I levels, normal or elevated GH levels, and lack of IGF-I response to GH treatment, IGF-I resistance is characterized by elevated IGF-I levels with normal/high GH levels. ...Complete GH
While insensitivity to GH (GHI) is characterized by low IGF-I levels, normal or elevated GH levels, and lack of IGF-I response …
Growth Hormone and Aging.
Hage C, Salvatori R. Hage C, et al. Endocrinol Metab Clin North Am. 2023 Jun;52(2):245-257. doi: 10.1016/j.ecl.2022.10.003. Epub 2022 Nov 16. Endocrinol Metab Clin North Am. 2023. PMID: 36948778 Review.
Growth hormone (GH) secretion declines with aging (somatopause). One of the most controversial issues in aging is GH treatment of older adults without evidence of pituitary pathology. ...Although most animal studies reported an association between decreased GH
Growth hormone (GH) secretion declines with aging (somatopause). One of the most controversial issues in aging is GH treatment …
Novel long-acting GH preparations.
Doknic M, Stojanovic M, Popovic V. Doknic M, et al. Pediatr Endocrinol Rev. 2014 Dec;12(2):206-12. Pediatr Endocrinol Rev. 2014. PMID: 25581986 Review.
Currently a variety of modified GH molecules which delay GH clearance (CTP modified GH, recombinant polypeptide XTEN, GH conjugated with albumin, GH linked to immunoglobulin) are studied and the ongoing studies are in different phases (from I-II …
Currently a variety of modified GH molecules which delay GH clearance (CTP modified GH, recombinant polypeptide XTEN, …
Long-acting growth hormone in 2022.
Steiner M, Frank J, Saenger P. Steiner M, et al. Pediatr Investig. 2023 Jan 3;7(1):36-42. doi: 10.1002/ped4.12358. eCollection 2023 Mar. Pediatr Investig. 2023. PMID: 36967745 Free PMC article. Review.
After the isolation of pituitary growth hormone (GH) in 1957, this form of GH, always in limited supply, was the only drug available for the treatment of GH deficiency. ...New indications for GH in pediatrics and adult medicine were developed. Treatmen …
After the isolation of pituitary growth hormone (GH) in 1957, this form of GH, always in limited supply, was the only drug ava …
Laboratory assessment of GH.
Strasburger CJ. Strasburger CJ. Growth Horm IGF Res. 1998 Feb;8 Suppl A:41-6. doi: 10.1016/s1096-6374(98)80008-7. Growth Horm IGF Res. 1998. PMID: 10993590 Review.
Final proof of the diagnosis, however, is sought by measurement of GH levels in serum after dynamic provocative testing of GH secretion. Although arbitrary cut-off levels exist, below which the maximum GH peak should be found in different provocative tests, t …
Final proof of the diagnosis, however, is sought by measurement of GH levels in serum after dynamic provocative testing of GH
Growth hormone isoforms.
Baumann GP. Baumann GP. Growth Horm IGF Res. 2009 Aug;19(4):333-40. doi: 10.1016/j.ghir.2009.04.011. Epub 2009 May 24. Growth Horm IGF Res. 2009. PMID: 19467614 Review.
The GH gene cluster on chromosome 17q contains 2 GH genes (GH1 or GH-N and GH2 or GH-V) in addition to 2(-3) genes encoding the related chorionic somatomammotropin. ...Oligomeric GH forms have variably diminished bioactivity compared to monomeri …
The GH gene cluster on chromosome 17q contains 2 GH genes (GH1 or GH-N and GH2 or GH-V) in addition to 2(-3) gen …
Effect of GH/IGF-1 on Bone Metabolism and Osteoporsosis.
Locatelli V, Bianchi VE. Locatelli V, et al. Int J Endocrinol. 2014;2014:235060. doi: 10.1155/2014/235060. Epub 2014 Jul 23. Int J Endocrinol. 2014. PMID: 25147565 Free PMC article. Review.
Eighteen clinical studies considered the effect with GH treatment, fourteen studies reported the clinical effects with IGF-1 administration, and seven related to the GH/IGF-1 effect on bone healing. ...GH interacts with sex steroids in the anabolic process. …
Eighteen clinical studies considered the effect with GH treatment, fourteen studies reported the clinical effects with IGF-1 administ …
Metabolic consequences of GH deficiency.
Jørgensen JO, Vestergaard E, Gormsen L, Jessen N, Nørrelund H, Christiansen JS, Møller N. Jørgensen JO, et al. J Endocrinol Invest. 2005;28(5 Suppl):47-51. J Endocrinol Invest. 2005. PMID: 16114276 Review.
Patients with active acromegaly are insulin resistant and glucose intolerant, whereas children with GH deficiency are insulin sensitive and may develop fasting hypoglycemia. Surprisingly, however, hypopituitary adults with unsubstituted GH deficiency tend to be insu …
Patients with active acromegaly are insulin resistant and glucose intolerant, whereas children with GH deficiency are insulin sensiti …
Growth hormone (GH), brain development and neural stem cells.
Waters MJ, Blackmore DG. Waters MJ, et al. Pediatr Endocrinol Rev. 2011 Dec;9(2):549-53. Pediatr Endocrinol Rev. 2011. PMID: 22397139 Review.
A range of observations support a role for GH in development and function of the brain. These include altered brain structure in GH receptor null mice, and impaired cognition in GH deficient rodents and in a subgroup of GH receptor defective patients ( …
A range of observations support a role for GH in development and function of the brain. These include altered brain structure in G
70,095 results
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