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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1978 1
1980 1
1983 1
1984 2
1985 2
1986 7
1987 1
1988 5
1989 4
1990 1
1991 1
2015 2
2016 1
2017 2
2018 1
2020 2
2021 2
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35 results
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Page 1
Development of an RNAi therapeutic for alpha-1-antitrypsin liver disease.
Wooddell CI, Blomenkamp K, Peterson RM, Subbotin VM, Schwabe C, Hamilton J, Chu Q, Christianson DR, Hegge JO, Kolbe J, Hamilton HL, Branca-Afrazi MF, Given BD, Lewis DL, Gane E, Kanner SB, Teckman JH. Wooddell CI, et al. Among authors: given bd. JCI Insight. 2020 Jun 18;5(12):e135348. doi: 10.1172/jci.insight.135348. JCI Insight. 2020. PMID: 32379724 Free PMC article.
RNAi-based treatment of chronically infected patients and chimpanzees reveals that integrated hepatitis B virus DNA is a source of HBsAg.
Wooddell CI, Yuen MF, Chan HL, Gish RG, Locarnini SA, Chavez D, Ferrari C, Given BD, Hamilton J, Kanner SB, Lai CL, Lau JYN, Schluep T, Xu Z, Lanford RE, Lewis DL. Wooddell CI, et al. Among authors: given bd. Sci Transl Med. 2017 Sep 27;9(409):eaan0241. doi: 10.1126/scitranslmed.aan0241. Sci Transl Med. 2017. PMID: 28954926 Free PMC article. Clinical Trial.
RNA Interference Therapy With ARC-520 Results in Prolonged Hepatitis B Surface Antigen Response in Patients With Chronic Hepatitis B Infection.
Yuen MF, Schiefke I, Yoon JH, Ahn SH, Heo J, Kim JH, Lik Yuen Chan H, Yoon KT, Klinker H, Manns M, Petersen J, Schluep T, Hamilton J, Given BD, Ferrari C, Lai CL, Locarnini SA, Gish RG. Yuen MF, et al. Among authors: given bd. Hepatology. 2020 Jul;72(1):19-31. doi: 10.1002/hep.31008. Epub 2020 Apr 23. Hepatology. 2020. PMID: 31654573 Free PMC article. Clinical Trial.
Pharmacokinetics and pharmacodynamics of dilevalol.
Tenero DM, Bottorff MB, Given BD, Kramer WG, Affrime MB, Patrick JE, Lalonde RL. Tenero DM, et al. Among authors: given bd. Clin Pharmacol Ther. 1989 Dec;46(6):648-56. doi: 10.1038/clpt.1989.201. Clin Pharmacol Ther. 1989. PMID: 2598569
Safety, Tolerability, and Pharmacokinetics of ARC-520 Injection, an RNA Interference-Based Therapeutic for the Treatment of Chronic Hepatitis B Virus Infection, in Healthy Volunteers.
Schluep T, Lickliter J, Hamilton J, Lewis DL, Lai CL, Lau JY, Locarnini SA, Gish RG, Given BD. Schluep T, et al. Among authors: given bd. Clin Pharmacol Drug Dev. 2017 Jul;6(4):350-362. doi: 10.1002/cpdd.318. Epub 2016 Dec 12. Clin Pharmacol Drug Dev. 2017. PMID: 27739230 Free PMC article. Clinical Trial.
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