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GLIPR1L1 is an IZUMO-binding protein required for optimal fertilization in the mouse.
Gaikwad AS, Anderson AL, Merriner DJ, O'Connor AE, Houston BJ, Aitken RJ, O'Bryan MK, Nixon B. Gaikwad AS, et al. BMC Biol. 2019 Oct 31;17(1):86. doi: 10.1186/s12915-019-0701-1. BMC Biol. 2019. PMID: 31672133 Free PMC article.
At least two of these complexes contain IZUMO1 in partnership with GLI pathogenesis-related 1 like 1 (GLIPR1L1). This interaction is associated with lipid rafts and is dynamically remodeled upon the induction of acrosomal exocytosis in preparation for sperm adhesion to the …
At least two of these complexes contain IZUMO1 in partnership with GLI pathogenesis-related 1 like 1 (GLIPR1L1). This interaction is …
Identification and characterization of RTVP1/GLIPR1-like genes, a novel p53 target gene cluster.
Ren C, Ren CH, Li L, Goltsov AA, Thompson TC. Ren C, et al. Genomics. 2006 Aug;88(2):163-72. doi: 10.1016/j.ygeno.2006.03.021. Epub 2006 May 22. Genomics. 2006. PMID: 16714093 Free article.
GLIPR1L1 has two and GLIPR1L2 has five differentially spliced isoforms. Protein homology search revealed that hRTVP-1 gene cluster members share a high degree of identity and homology. GLIPR1L1 is testis-specific, whereas GLIPR1L2 is expressed in different types of …
GLIPR1L1 has two and GLIPR1L2 has five differentially spliced isoforms. Protein homology search revealed that hRTVP-1 gene cluster me …
Glioma pathogenesis-related 1-like 1 is testis enriched, dynamically modified, and redistributed during male germ cell maturation and has a potential role in sperm-oocyte binding.
Gibbs GM, Lo JC, Nixon B, Jamsai D, O'Connor AE, Rijal S, Sanchez-Partida LG, Hearn MT, Bianco DM, O'Bryan MK. Gibbs GM, et al. Endocrinology. 2010 May;151(5):2331-42. doi: 10.1210/en.2009-1255. Epub 2010 Mar 10. Endocrinology. 2010. PMID: 20219979
Specifically data from a number of systems suggests that sequences within the C-terminal CAP domain of CAP proteins have the ability to promote cell-cell adhesion. Herein we cloned mouse Glipr1l1 and have shown it has a testis-enriched expression profile. GLIPR1L1 i …
Specifically data from a number of systems suggests that sequences within the C-terminal CAP domain of CAP proteins have the ability to prom …
Bovine sperm raft membrane associated Glioma Pathogenesis-Related 1-like protein 1 (GliPr1L1) is modified during the epididymal transit and is potentially involved in sperm binding to the zona pellucida.
Caballero J, Frenette G, D'Amours O, Belleannée C, Lacroix-Pepin N, Robert C, Sullivan R. Caballero J, et al. J Cell Physiol. 2012 Dec;227(12):3876-86. doi: 10.1002/jcp.24099. J Cell Physiol. 2012. PMID: 22552861
These results suggest that the N-glycosylation moiety of GliPr1L1 is processed during the transit in the caput. Western blots demonstrated that GliPr1L1 was associated with the sperm plasma membrane preparation. ...GliPr1L1 was localized on sperm equatorial s …
These results suggest that the N-glycosylation moiety of GliPr1L1 is processed during the transit in the caput. Western blots demonst …
Screening Indels from the whole genome to identify the candidates and their association with economic traits in several goat breeds.
Saleh AA, Xue L, Zhao Y. Saleh AA, et al. Funct Integr Genomics. 2023 Feb 9;23(1):58. doi: 10.1007/s10142-023-00981-w. Funct Integr Genomics. 2023. PMID: 36757519
Then, three selected candidate Indels rs668795676, rs657996810, and rs669452874 of the three genes SUFU, SYCP2L and GLIPR1L1, respectively, have been chosen, based on the results of prior GWAS across the genome, and examined for their association with body weight and dimen …
Then, three selected candidate Indels rs668795676, rs657996810, and rs669452874 of the three genes SUFU, SYCP2L and GLIPR1L1, respect …
CD9-positive microvesicles mediate the transfer of molecules to Bovine Spermatozoa during epididymal maturation.
Caballero JN, Frenette G, Belleannée C, Sullivan R. Caballero JN, et al. PLoS One. 2013 Jun 13;8(6):e65364. doi: 10.1371/journal.pone.0065364. Print 2013. PLoS One. 2013. PMID: 23785420 Free PMC article.
They contain tetraspanin CD9 in addition to other proteins involved in sperm maturation such as P25b, GliPr1L1, and MIF. In order to study the mechanism of protein transfer to sperm, DilC12-labeled unfractionated epididymosomes or CD9-positive microvesicles were coincubate …
They contain tetraspanin CD9 in addition to other proteins involved in sperm maturation such as P25b, GliPr1L1, and MIF. In order to …
Examining Hedgehog pathway genes GLI3, SHH, and PTCH1 and the p53 target GLIPR1/GLIPR1L1/GLIPR1L2 gene cluster using fluorescence in situ hybridization uncovers GLIPR1/GLIPR1L1/GLIPR1L2 deletion in 9% of patients with multiple myeloma.
Tam M, Lin P, Hu P, Lennon PA. Tam M, et al. J Assoc Genet Technol. 2010;36(3):111-4. J Assoc Genet Technol. 2010. PMID: 20978342
This study focuses on detecting copy number variations for the GLIPR1/GLIPR1L1/GLIPR1L2 gene cluster of the p53 pathway and three elements of the HH pathway, SHH, PTCH1 and GLI3 in multiple myeloma (MM) using fluorescence in situ hybridization (FISH). ...Further studies sh …
This study focuses on detecting copy number variations for the GLIPR1/GLIPR1L1/GLIPR1L2 gene cluster of the p53 pathway and three ele …
Detailed genome-wide SNP analysis of major salivary carcinomas localizes subtype-specific chromosome sites and oncogenes of potential clinical significance.
Zhang L, Mitani Y, Caulin C, Rao PH, Kies MS, Saintigny P, Zhang N, Weber RS, Lippman SM, El-Naggar AK. Zhang L, et al. Am J Pathol. 2013 Jun;182(6):2048-57. doi: 10.1016/j.ajpath.2013.02.020. Epub 2013 Apr 10. Am J Pathol. 2013. PMID: 23583282 Free PMC article.
Tumor-specific amplicons were identified at 11q23.3 (PVRL1) in ACC, 11q13.3 (NUMA1) in MEC, and 6p21.1 (CCND3), 9p13.2 (PAX5), 12q15 (CNOT2/RAB3IP), 12q21.1 (GLIPR1L1), and 17q12 (ERBB2/CCL4) in SDC. A comparative CNA analysis of fusion-positive and fusion-negative ACCs an …
Tumor-specific amplicons were identified at 11q23.3 (PVRL1) in ACC, 11q13.3 (NUMA1) in MEC, and 6p21.1 (CCND3), 9p13.2 (PAX5), 12q15 (CNOT2/ …