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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 2
2004 1
2005 3
2006 3
2007 2
2009 4
2010 3
2011 5
2012 2
2013 5
2014 4
2015 5
2016 7
2017 12
2018 5
2019 11
2020 12
2021 12
2022 9
2023 8
2024 2

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105 results

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Page 1
Trends in GPCR drug discovery: new agents, targets and indications.
Hauser AS, Attwood MM, Rask-Andersen M, Schiöth HB, Gloriam DE. Hauser AS, et al. Among authors: gloriam de. Nat Rev Drug Discov. 2017 Dec;16(12):829-842. doi: 10.1038/nrd.2017.178. Epub 2017 Oct 27. Nat Rev Drug Discov. 2017. PMID: 29075003 Free PMC article. Review.
Pharmacogenomics of GPCR Drug Targets.
Hauser AS, Chavali S, Masuho I, Jahn LJ, Martemyanov KA, Gloriam DE, Babu MM. Hauser AS, et al. Among authors: gloriam de. Cell. 2018 Jan 11;172(1-2):41-54.e19. doi: 10.1016/j.cell.2017.11.033. Epub 2017 Dec 14. Cell. 2018. PMID: 29249361 Free PMC article.
Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs.
Avet C, Mancini A, Breton B, Le Gouill C, Hauser AS, Normand C, Kobayashi H, Gross F, Hogue M, Lukasheva V, St-Onge S, Carrier M, Héroux M, Morissette S, Fauman EB, Fortin JP, Schann S, Leroy X, Gloriam DE, Bouvier M. Avet C, et al. Among authors: gloriam de. Elife. 2022 Mar 18;11:e74101. doi: 10.7554/eLife.74101. Elife. 2022. PMID: 35302493 Free PMC article.
Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists.
Zhang X, Belousoff MJ, Zhao P, Kooistra AJ, Truong TT, Ang SY, Underwood CR, Egebjerg T, Šenel P, Stewart GD, Liang YL, Glukhova A, Venugopal H, Christopoulos A, Furness SGB, Miller LJ, Reedtz-Runge S, Langmead CJ, Gloriam DE, Danev R, Sexton PM, Wootten D. Zhang X, et al. Among authors: gloriam de. Mol Cell. 2020 Nov 5;80(3):485-500.e7. doi: 10.1016/j.molcel.2020.09.020. Epub 2020 Oct 6. Mol Cell. 2020. PMID: 33027691 Free article.
Structural insights into the lipid and ligand regulation of serotonin receptors.
Xu P, Huang S, Zhang H, Mao C, Zhou XE, Cheng X, Simon IA, Shen DD, Yen HY, Robinson CV, Harpsøe K, Svensson B, Guo J, Jiang H, Gloriam DE, Melcher K, Jiang Y, Zhang Y, Xu HE. Xu P, et al. Among authors: gloriam de. Nature. 2021 Apr;592(7854):469-473. doi: 10.1038/s41586-021-03376-8. Epub 2021 Mar 24. Nature. 2021. PMID: 33762731
Ligand selectivity hotspots in serotonin GPCRs.
Simon IA, Bjørn-Yoshimoto WE, Harpsøe K, Iliadis S, Svensson B, Jensen AA, Gloriam DE. Simon IA, et al. Among authors: gloriam de. Trends Pharmacol Sci. 2023 Dec;44(12):978-990. doi: 10.1016/j.tips.2023.09.012. Epub 2023 Oct 31. Trends Pharmacol Sci. 2023. PMID: 37914598 Free article. Review.
G protein-coupled receptor pharmacology-The next generation.
Bräuner-Osborne H, Rosenkilde MM, Gether U, Gloriam DE. Bräuner-Osborne H, et al. Among authors: gloriam de. Basic Clin Pharmacol Toxicol. 2020 Jun;126 Suppl 6:3-4. doi: 10.1111/bcpt.13291. Epub 2019 Aug 21. Basic Clin Pharmacol Toxicol. 2020. PMID: 31301209 Free article. No abstract available.
Community guidelines for GPCR ligand bias: IUPHAR review 32.
Kolb P, Kenakin T, Alexander SPH, Bermudez M, Bohn LM, Breinholt CS, Bouvier M, Hill SJ, Kostenis E, Martemyanov KA, Neubig RR, Onaran HO, Rajagopal S, Roth BL, Selent J, Shukla AK, Sommer ME, Gloriam DE. Kolb P, et al. Among authors: gloriam de. Br J Pharmacol. 2022 Jul;179(14):3651-3674. doi: 10.1111/bph.15811. Epub 2022 Mar 27. Br J Pharmacol. 2022. PMID: 35106752 Free PMC article. Review.
Novel approaches leading towards peptide GPCR de-orphanisation.
Hauser AS, Gloriam DE, Bräuner-Osborne H, Foster SR. Hauser AS, et al. Among authors: gloriam de. Br J Pharmacol. 2020 Mar;177(5):961-968. doi: 10.1111/bph.14950. Epub 2020 Feb 3. Br J Pharmacol. 2020. PMID: 31863461 Free PMC article. Review.
The G protein database, GproteinDb.
Pándy-Szekeres G, Esguerra M, Hauser AS, Caroli J, Munk C, Pilger S, Keserű GM, Kooistra AJ, Gloriam DE. Pándy-Szekeres G, et al. Among authors: gloriam de. Nucleic Acids Res. 2022 Jan 7;50(D1):D518-D525. doi: 10.1093/nar/gkab852. Nucleic Acids Res. 2022. PMID: 34570219 Free PMC article.
105 results