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Designing Tailored Thiosemicarbazones with Bespoke Properties: The Styrene Moiety Imparts Potent Activity, Inhibits Heme Center Oxidation, and Results in a Novel "Stealth Zinc(II) Complex".
Dharmasivam M, Kaya B, Wijesinghe T, Gholam Azad M, Gonzálvez MA, Hussaini M, Chekmarev J, Bernhardt PV, Richardson DR. Dharmasivam M, et al. Among authors: gonzalvez ma. J Med Chem. 2023 Jan 26;66(2):1426-1453. doi: 10.1021/acs.jmedchem.2c01600. Epub 2023 Jan 17. J Med Chem. 2023. PMID: 36649565
Differential transmetallation of complexes of the anti-cancer thiosemicarbazone, Dp4e4mT: effects on anti-proliferative efficacy, redox activity, oxy-myoglobin and oxy-hemoglobin oxidation.
Dharmasivam M, Kaya B, Wijesinghe TP, Richardson V, Harmer JR, Gonzalvez MA, Lewis W, Azad MG, Bernhardt PV, Richardson DR. Dharmasivam M, et al. Among authors: gonzalvez ma. Chem Sci. 2023 Dec 15;15(3):974-990. doi: 10.1039/d3sc05723b. eCollection 2024 Jan 17. Chem Sci. 2023. PMID: 38239703 Free PMC article.
13 results